探讨益气利湿降浊汤联合中药灌肠治疗早期糖尿病肾病临床效果

目的对益气利湿降浊汤联合中药灌肠在早期糖尿病肾病中的治疗效果进行探讨。方法纳入早期糖尿病肾病患者40例参与此次研究,并将其设为实验组,予以益气利湿降浊汤联合中药灌肠治疗;同期纳入早期糖尿病肾病患者40例设为对照组,予以常规治疗。比较两组患者在此次治疗过程中的临床情况,并比较两组患者的治疗效果以及肾功能改善情况。结果实验组的总有效率高于对照组(P0.05),差异具有统计学意义;实验组治疗后的肾功能指标优于大于对照组(P0.05),差异具有统计学意义。结论应用益气利湿降浊汤联合中药灌肠对早期糖尿病肾病患者实施治疗,可改善患者的病情症状以及肾功能指标。     

益气培元固肾汤联合耳穴贴敷治疗糖尿病肾病蛋白尿的临床分析

目的:分析益气培元固肾汤联合耳穴贴敷治疗糖尿病肾病蛋白尿的临床效果.方法:在2018年9月—2020年9月期间,抽取本院接收的60例糖尿病肾病蛋白尿患者作为研究对象,并通过随机数字表法将其分为对照组和观察组各30例.两组均给予基本治疗,对照组在此基础上给予口服厄贝沙坦150 mg,每日1次,观察组在治疗组基础上予以益气培元固肾汤联合耳穴贴敷治疗,比较两组的临床疗效、治疗前后SCr、BUN、UAER、FPG、2 hPG、24 h蛋白尿、中医证候积分.结果:治疗后,观察组的临床总有效率(93.33％)明显高于对照组(73.33％)(P<0.05);同时,两组的SCr、BUN、UAER、FPG、2 hPG水平均有所降低,24 h蛋白尿有所减少,且观察组降低幅度和减少幅度优于对照组(P<0.05);且两组的主症、次症中医证候积分均有所降低,且观察组的降低幅度优于对照组(P<0.05).结论:在糖尿病肾病蛋白尿患者中实施益气培元固肾汤联合耳穴贴敷治疗,能进一步改善患者的肾功能及蛋白尿症状,并提升临床治疗效果.     

中药滋阴通络汤联合穴位贴敷对早期糖尿病肾病患者肾功能改善作用探究

目的:探讨中药滋阴通络汤联合穴位贴敷对早期糖尿病肾病患者肾功能的改善效果.方法:选择我院2019年1月～2019年10月期间收治的40例早期糖尿病肾病患者,随机分组例观察组为20和对照组20例,对照组患者应用常规对症治疗,观察组患者应用中药滋阴通络汤联合穴位贴敷法进行治疗,比较两组患者临床治疗效果、治疗前后血肌酐、血清白蛋白、BUN以及24 h尿蛋白定量指标的改善情况以及TNF-α、IL-6等炎性因子的改善情况.结果:治疗后观察组患者显效9例,有效8例,无效3例,总有效率为85％,对照组患者各项数据分别为6例、5例和9例,有效率为55％,比观察组更低,P<0.05.治疗前两组患者血肌酐、血尿素氮、血清白蛋白、24 h尿蛋白定量以及TNF-α、IL-6炎性因子指标数值非常相似,P>0.05,治疗后两组患者的血肌酐、24 h尿蛋白定量和血尿素氮数值均降低,血清白蛋白数值提升,TNF-α与IL-6炎性因子指标显著下降,P<0.05,观察组对比对照组患者指标改善更明显,表明疗效更好,P<0.05.结论:联合应用中药滋阴通络与穴位贴敷有助于改善早期糖尿病肾病患者的肾功能情况和炎性指标,保障临床疗效,具有很高的临床应用价值.     

中药灌肠治疗糖尿病肾病肾功能不全临床研究

目的 考察中药免煎制剂灌肠方剂治疗糖尿病肾病肾功能不全的疗效及安全性.方法 采用随机分组对照观察法,将108例糖尿病肾病肾功能不全患者随机分为治疗组58例与对照组50例,分别给予中药免煎制剂灌肠方剂保留灌肠和常规西药治疗,观察其血糖、血压、临床疗效及血BUN、Scr的改变.结果 治疗组总有效率86%,对照组总有效率68%,差异有显著性意义(χ2=25.85,P<0.05).治疗组经中药灌肠后Scr下降19.8%,BUN下降44.8%,与治疗前比较下降明显(P<0.05).结论 中药灌肠液对糖尿病肾病肾功能不全具有明显延缓病程发展,改善肾功能的作用.     

前列地尔注射液结合肾衰泻浊汤治疗糖尿病肾病的临床效果观察

目的:探讨前列地尔注射液联合肾衰泻浊汤治疗糖尿病肾病的临床疗效。方法:选取2012年1月~2013年12月我院收治的糖尿病肾病患者84例,将其分为观察组和对照组各42例;对照组单纯应用肾衰泻浊汤治疗,观察组给予前列地尔注射液联合肾衰泻浊汤治疗,比较2组患者临床疗效。结果:观察组总有效率为95.2%,对照组为83.3%,观察组总有效率显著高于对照组(P<0.05)。2组患者BUN、Scr及尿蛋白水平较治疗前均明显降低(P<0.05),且观察组各项肾功能指标均显著优于对照组(P<0.05)。结论:前列地尔注射液联合肾衰泻浊汤治疗糖尿病肾病效果显著,有效促进患者肾功能恢复,值得在临床上应用和推广。     

黄龙固本汤对2型糖尿病肾病早期微量蛋白尿患者肾功能的影响

目的:观察黄龙固本汤治疗2型糖尿病肾病早期微量蛋白尿患者的临床疗效,并观察其对患者肾功能、血糖及证候积分的影响。方法:80例2型糖尿病早期微量蛋白尿患者随机平均分为观察组和对照组。对照组给予基础治疗,观察组在对照组治疗基础上给予黄龙固本汤口服,疗程为3个月。比较治疗前后患者尿微量白蛋白/肌酐(microalbuminuria/creatinine,ACR)、肌酐(creatinine,Cr)、血尿素氮(blood urea nitrogen,BUN)、糖化血红蛋白(glycosylated hemoglobin,HbA1c)、空腹血糖(fasting plasma glucose,FPG)、餐后血糖(postprandial blood glucose,PBG)水平,中医证候总积分,并比较临床疗效。结果:治疗后两组患者中医证候总积分均下降,但观察组下降幅度明显高于对照组(P0.01)。观察组和对照组有效率分别为87.5%和67.5%,两组有效率比较,差异有统计学意义(P0.05)。与治疗前比较,治疗后两组患者ACR、Cr、BUN、HbA1c、FPG、PBG均显著改善,治疗组以上指标改善显著优于对照组,差异均有统计学意义(P0.05)。结论:黄龙固本汤治疗2型糖尿病肾病早期微量蛋白尿患者临床疗效显著,可显著降低患者中医证候积分、血糖,改善患者肾功能。     

芪藿复方合剂加减方配合中药灌肠治疗糖尿病肾病肾功能异常疗效观察

目的:观察芪藿复方合剂加减方配合中药灌肠对糖尿病肾病肾功能异常的临床疗效。方法:63例糖尿病肾病肾功能异常患者随机分为治疗组31例和对照组32例,两组均给予西医对症处理,治疗组加用芪藿复方合剂配合中药灌肠,检测治疗组及对照组治疗前、治疗后3个月的肾功能、血脂、血常规、血浆白蛋白等及中医证候评分。结果:治疗组中医证候疗效总有效率为80.64%,明显优于对照组53%,治疗组治疗后实验室各项指标改善明显,对照组治疗后不明显;治疗组患者在治疗后症状积分下降明显,而对照组下降不明显。结论:芪藿复方合剂配合中药灌肠治疗可改善糖尿病肾病肾功能异常患者的营养状况,改善肾功能,提高生存质量,对糖尿病肾病有较好的临床治疗作用。     

降糖益肾汤联合氯沙坦钾治疗早期糖尿病肾病患者的临床疗效*

目的 观察降糖益肾汤联合氯沙坦钾治疗早期糖尿病肾病患者的疗效和对患者肾功能、血清胱抑素C（CysC）、同型半胱氨酸（Hcy）的影响。方法 纳入的82例早期糖尿病肾病患者根据随机表法分为对照组与观察组，各41例。观察组给予降糖益肾汤联合氯沙坦钾治疗，对照组给予氯沙坦钾治疗。2组疗程均为8周。比较2组治疗前后尿微量白蛋白（mALB）、血肌酐（Scr）、尿素氮（BUN）、CysC、Hcy的变化。结果 治疗后，2组mALB、Scr、BUN较治疗前降低（观察组：t=39.007、21.271、19.667，对照组：t=21.509、5.473、9.437，P<0.05）；观察组mALB、Scr、BUN低于对照组（t=14.989、16.552、7.855，P<0.05）。治疗后2组血清CysC、Hcy水平较治疗前降低（观察组：t=26.667、13.343，对照组：t=12.866、6.519，P<0.05）；观察组血清CysC、Hcy水平低于对照组（t=10.970、9.822，P<0.05）。观察组总有效率（92.68%）高于对照组（68.29%）（P<0.05）。结论 降糖益肾汤联合氯沙坦钾治疗早期糖尿病肾病患者的疗效明显，可改善肾功能，降低血清CysC、Hcy水平。     

补气益肾降浊汤治疗早期糖尿病肾病的临床观察

[目的]观察中西医结合治疗早期糖尿病肾病的临床效果。[方法]2003年12月-2005年12月来我院治疗的早期糖尿病肾病患者62例,随机分为观察组和对照组。在对症治疗的基础上,对照组给予前列地尔,观察组采用补气益肾降浊汤联合前列地尔。[结果]采用中西医结合治疗早期糖尿病肾病(EDN),有效率为90.62%,有效率显著高于对照组;同时UAER观察组比对照组下降更明显,并且显著改善患者的血脂状况。[结论]应用中西医结合治疗早期糖尿病肾病,能显著改善早期糖尿病肾病的临床症状,而且能明显减少尿蛋白,具有临床推广价值。     

调肝降浊灌肠汤治疗慢性肾功能不全临床观察

目的:探讨中药调肝降浊灌肠汤保留灌肠治疗慢性肾功能不全(CRF)的临床疗效。方法:60例CRF患者随机分为灌肠组(A组)30例,使用调肝降浊灌肠汤保留灌肠;对照组(B组)30例,予科素亚50mg/d,口服,每日1次。均以2w为1个疗程。分别观察其临床症状、尿素氮、肌酐及肌酐清除率变化。结果:A组治疗后症状评分、BUN、Scr水平均较治疗前明显降低,肌酐清除率较治疗前明显升高(P<0.05);B组治疗后症状评分、Scr水平较治疗前明显降低,肌酐清除率较治疗前明显升高(P<0.05),治疗前后尿素氮比较差异不显著。两组间症状和肾功能的改善水平相当。结论:中药复方调肝降浊灌肠汤保留灌肠与科素亚均可改善临床症状,降低增高的血清肌酐,提高肌酐清除率,从而起到延缓慢性肾功能衰竭进展,保护肾功能的目的。     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Acupuncture Treatment of Vomiting

CASE HISTORY A female patient, 46 years old, head of the foreign affairs department of a certain university in Beijing, paid her first visit on October 9, 2006, with the chief complaint of vomiting for one month. She got vomiting after meals in early September. Before that, she had discomfortable sensation in the stomach due to angry with others, but she didn't pay much attention. Later, it developed into vomiting after eating. After the vomiting, the discomfort would be relieved, but with slight hypodynamia. She was once diagnosed as having 'neurogenic vomiting'. Having taken some western and Chinese drugs, the above symptoms were a little bit improved, but she would have nausea upon eating and with regurgitation. Because of the fear for vomiting, she did not dare to have food intake, with body weight reduction of 6 kilos in one month.     

Qiu Baoguo''''s Experience in Treating Consumptive Syndromes after Radio-Chemotherapies

Radiotherapy and chemotherapy are the important modern medical therapies for malignant tumors,yet they can also bring about serious local and systemic toxic side reactions so to decrease the patient;'s life quality,manifested by a series of consumptive symptoms.Having engaged in the combined work of Chinese and western medicine for nearly 50 years,the research fellow Qiu Baoguo in Henan Provincial Academy of TCM has developed his unique views on the TCM study of consumptive syndromes.The author of this essay had once the fortune tO follow Dr.Qiu in clinic,and specially would like to introduce in the following Dr.Qiu's experience in treating consumptive syndromes after radio-chemotherapies for patients with malignant tumor.     

Insomnia Due to Deficiency of Both the Heart and Spleen Treated by Acupuncture-Moxibustion and Chinese Tuina

OBJECTIVE: To observe therapeutic effects of the comprehensive therapy of acupuncture-moxibustion and Chinese Tuina for treatment of insomnia due to deficiency of both the heart and spleen. METHODS: 92 cases were divided randomly into the treatment group (treated by acupuncture-moxibustion and Chinese Tuina) and the control group (treated by acupuncture-moxibustion). RESULTS: The therapeutic effect of the treatment group was obviously superior to that of the control group (the CHI2 test showed P < 0.01). CONCLUSIONS: The comprehensive therapy of acupuncture-moxibustion and Chinese Tuina can give marked therapeutic effects for treatment of insomnia due to deficiency of both the heart and spleen.     

Analysis of CK-19,PDX-1,Nestin,Ngn3 in different donor islet purity in rats

Objective: To investigate if there are the CK-19, PDX-1, Nestin, Ngn3 positive cells in the donor islets of different purity in rats. Methods: Thirty male adult SD rats were randomly divided into 3 groups. Islets were isolated using digestion by ductal injection of collagenase. Group Ⅰ (n=10): Separating cell preparations were not purified, Group Ⅱ(n=10): Islet sediment was purified with 25% Ficoll400 ,Group Ⅲ (n=10): Islet sediment was purified with 25% and 11% Ficoll-400. The levels of protein of CK-19, PDX-1, Nestin and Ngn3 were detected by immunohistochemistry and the mRNA of CK-19, PDX-1, Nestin, Ngn3 was amplified by RT-PCR. Results: After two different purification methods applied, three islet preparations of different purities were obtained. The difference of islet purity was significant among various groups (P＜0.05). Compared with group Ⅱ and group Ⅲ,the protein and mRNA of CK-19, PDX-1, Nestin,Ngn3 were both higher in group Ⅰ; group Ⅲ was poorly expressed. Conclusions: The three different islet purity donor islet have different CK-19, PDX-1, Nestin, Ngn3 positive cells within them, indicating that there are some islet stem cells in the purified donor islet.     

Dr.Zhang Ren''''s Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

Luo Lingjie''''s Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.