原发性眶内卵黄囊瘤1例影像学表现

<正>卵黄囊瘤（YST）又名内胚窦瘤（EST）,是一种少见的高度恶性生殖细胞肿瘤,多见于儿童,主要发生于性腺（睾丸和卵巢）,而发生于性腺外者,多位于靠近身体中线的部位,如骶尾区、子宫、阴道、前列腺、腹膜后、肝脏、纵隔、松果体区和第三脑室等[1-2]。原发于眶内卵黄囊瘤极为罕见,南昌大学第一附属医院2019年7月收治1例原发性眶内YST患者,现结合相关文献,对其CT、MRI影像学表现进行回顾性分析,旨在提高对本病的认识。1 临床资料     

关于性腺内与性腺外卵黄囊瘤诊断的几个问题

<正> 卵黄囊瘤又称内胚窦瘤,是恶性度极高的肿瘤,最常见于性腺内(卵巢及睾丸),也可见于性腺外的身体正中线部位(例如外阴、阴道、子宫体、前列腺、骶前、骶尾部、腹后壁、肝、胃底、腹壁脐部、纵隔、松果     

儿童卵黄囊瘤病理学特征及鉴别诊断

目的 了解儿童卵黄囊瘤（YST）的组织形态学特征,明确免疫组织化学特点及其在YST病理学诊断中的作用,探讨YST鉴别诊断要点。方法 回顾总结21例YST(性腺8例,非性腺13例)的组织形态学及免疫组织化学特征。结果 YST的组织形态学表现多样,具有微囊和网状结构17例,内胚窦结构16例,腺管—腺泡结构10例,乳头状结构8例,巨囊结构和肠型结构各3例,多囊泡卵黄囊样结构2例,黏液瘤样结构1例。免疫组织化学染色甲胎蛋白（AFP）阳性表达20例(95.24%),细胞角蛋白(CK)阳性表达21例(100%),波形蛋白（Vim）阳性表达16例(76.19%)。结论 儿童YST可发生于性腺（睾丸和卵巢）,亦可发生于非性腺部位（骶尾部、盆腹腔、小脑和软组织等）。YST组织形态表现具多样性,常见特征性结构有微囊和网状结构、内胚窦结构、腺管—腺泡结构和乳头状结构,巨囊结构、肠型结构、黏液瘤样结构和多囊泡卵黄囊样结构等较少见。组织形态学及免疫组织化学特征有助于明确YST的病理学诊断和鉴别诊断。     

性腺外卵黄囊瘤的临床CT分析

目的：探讨CT在性腺外卵黄囊瘤的临床应用价值。方法：回顾分析6例经病理证实的性腺外卵黄囊瘤的临床及CT影像表现。结果：3例发生于腹膜后,1例发生于纵隔内,2例发生于骶尾部。1例肿瘤呈囊实性,边缘强化明显,其内可能少量出血灶;5例呈不均匀软组织肿块,增强后均呈不均匀性强化,其内有不同程度坏死灶。结论：性腺外卵黄囊瘤的CT影像表现虽具有恶性肿瘤的特点。但缺乏特异性,确诊有赖于病理学检查。     

卵黄囊癌——附52例报告

卵黄囊癌是一种具有向胚外体腔分化倾向的恶性肿瘤,曾被 Teilum(1959)命名为内胚窦癌,后 Pierce 等(1970)认为以称“卵黄囊癌”较好。本瘤可发生于睾丸,卵巢及生殖腺外,一般是靠近躯体中线的部位。生殖腺外卵黄囊癌报导过的病例有骶尾部、盆腔、腹膜后、纵隔、颅内、上颌窦、肝、胃、女性的外阴、阴道、阔韧带、子宫及男性的前列腺等部。     

恶性卵黄囊瘤12例临床病理分析

12例恶性卵黄囊瘤 ,其中性腺 1 1例 (卵巢 4例、睾丸 7例 ) ,性腺外 (骶尾部 ) 1例。发病年龄以 30岁以下多见 ,占 91 .7%。病理上可见疏松网状结构、S- D小体、透明小体等特征性结构 ,临床测定血清 AFP,可以协助诊断 ,并可作为观察治疗效果 ,有无复发或转移的指标。治疗以手术切除为主 ,术中应将原发瘤及转移瘤切除干净 ,术后辅以化疗 ,可以提高生存率。恶性卵黄囊瘤预后不良     

小儿骶尾部卵黄囊癌甲胎蛋白免疫酶标定位观察及临床病理分析

卵黄囊癌是较少见的恶性生殖细胞肿瘤,多发生在卵巢和睾丸,偶尔发生在性腺外。在小儿的性腺外诸部位中,以骶尾部居多。由于该瘤可产生甲胎蛋白(AFP),应用免疫组织化学方法,观察AFP在瘤组织中的分布情况,对研究该瘤的形态与功     

原发性腹膜后内胚窦瘤误诊分析

内胚窦瘤（endodermal sinus tumor，EST）又称恶性卵黄囊瘤（yolk sac tumor），属少见高度恶性生殖细胞肿瘤，好发于儿童的性腺。少数可发生于性腺以外如纵隔、松果体、骶尾部、阴道及后腹膜区，原发于腹膜后区者更为少见…。原发性腹膜后内胚窦瘤（primary retroperitoneal endodermal sinus tumor．PREST）是一种极为少见的恶性肿瘤，容易误诊。     

恶性卵黄囊瘤(附47例病理分析)

恶性卵黄囊瘤(malignant yolk sac tumor)是近年来已获公认的一个肿瘤单元。本瘤由原始生殖细胞来源,具有拟似胚胎发育过程中卵黄囊结构的分化特征。可为纯粹性,或与其它生殖细胞性肿瘤并存。本瘤不太少见,既往常误认为胚胎性癌或恶性畸胎瘤。主要发生于性腺,亦可见于骶尾部等靠近中线的其它部位。发生于睾丸者,多见于婴幼儿,其中两岁以内手术者予后较好。发生于卵巢和性腺以外部位者,则多见于儿童和青少年,恶性度高,予后不良。     

卵黄囊瘤22例临床病理分析

目的:探讨卵黄囊瘤(YST)的临床病理学特征、诊断和鉴别诊断、治疗和预后.方法:收集22例YST的临床病理资料,采用免疫组织化学、过碘酸雪夫(PAS)染色等方法来研究其病理特征.结果:YST临床主要表现为腹部肿块、睾丸肿大或CT发现纵隔巨大肿块.组织学改变镜下见肿瘤组织呈现网状结构、S-D小体结构和伊红染的透明小体形成.免疫组织化学及特殊染色:肿瘤细胞显示:22例AFP阳性(100%),22例CK(Pan)阳性(100%),15例PLAP阳性(68%),13例CEA阳性(59%),17例PAS(77%)阳性,HCG肿瘤细胞均阴性.结论:S-D小体结构和免疫组化AFP阳性表达在YST的诊断和鉴别诊断方面较为重要的意义.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Acupuncture Treatment of Vomiting

CASE HISTORY A female patient, 46 years old, head of the foreign affairs department of a certain university in Beijing, paid her first visit on October 9, 2006, with the chief complaint of vomiting for one month. She got vomiting after meals in early September. Before that, she had discomfortable sensation in the stomach due to angry with others, but she didn't pay much attention. Later, it developed into vomiting after eating. After the vomiting, the discomfort would be relieved, but with slight hypodynamia. She was once diagnosed as having 'neurogenic vomiting'. Having taken some western and Chinese drugs, the above symptoms were a little bit improved, but she would have nausea upon eating and with regurgitation. Because of the fear for vomiting, she did not dare to have food intake, with body weight reduction of 6 kilos in one month.     

Qiu Baoguo''''s Experience in Treating Consumptive Syndromes after Radio-Chemotherapies

Radiotherapy and chemotherapy are the important modern medical therapies for malignant tumors,yet they can also bring about serious local and systemic toxic side reactions so to decrease the patient;'s life quality,manifested by a series of consumptive symptoms.Having engaged in the combined work of Chinese and western medicine for nearly 50 years,the research fellow Qiu Baoguo in Henan Provincial Academy of TCM has developed his unique views on the TCM study of consumptive syndromes.The author of this essay had once the fortune tO follow Dr.Qiu in clinic,and specially would like to introduce in the following Dr.Qiu's experience in treating consumptive syndromes after radio-chemotherapies for patients with malignant tumor.     

Insomnia Due to Deficiency of Both the Heart and Spleen Treated by Acupuncture-Moxibustion and Chinese Tuina

OBJECTIVE: To observe therapeutic effects of the comprehensive therapy of acupuncture-moxibustion and Chinese Tuina for treatment of insomnia due to deficiency of both the heart and spleen. METHODS: 92 cases were divided randomly into the treatment group (treated by acupuncture-moxibustion and Chinese Tuina) and the control group (treated by acupuncture-moxibustion). RESULTS: The therapeutic effect of the treatment group was obviously superior to that of the control group (the CHI2 test showed P < 0.01). CONCLUSIONS: The comprehensive therapy of acupuncture-moxibustion and Chinese Tuina can give marked therapeutic effects for treatment of insomnia due to deficiency of both the heart and spleen.     

Analysis of CK-19,PDX-1,Nestin,Ngn3 in different donor islet purity in rats

Objective: To investigate if there are the CK-19, PDX-1, Nestin, Ngn3 positive cells in the donor islets of different purity in rats. Methods: Thirty male adult SD rats were randomly divided into 3 groups. Islets were isolated using digestion by ductal injection of collagenase. Group Ⅰ (n=10): Separating cell preparations were not purified, Group Ⅱ(n=10): Islet sediment was purified with 25% Ficoll400 ,Group Ⅲ (n=10): Islet sediment was purified with 25% and 11% Ficoll-400. The levels of protein of CK-19, PDX-1, Nestin and Ngn3 were detected by immunohistochemistry and the mRNA of CK-19, PDX-1, Nestin, Ngn3 was amplified by RT-PCR. Results: After two different purification methods applied, three islet preparations of different purities were obtained. The difference of islet purity was significant among various groups (P＜0.05). Compared with group Ⅱ and group Ⅲ,the protein and mRNA of CK-19, PDX-1, Nestin,Ngn3 were both higher in group Ⅰ; group Ⅲ was poorly expressed. Conclusions: The three different islet purity donor islet have different CK-19, PDX-1, Nestin, Ngn3 positive cells within them, indicating that there are some islet stem cells in the purified donor islet.     

Dr.Zhang Ren''''s Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

Luo Lingjie''''s Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.