中国CDC信息安全体系建设分析

以中国CDC的网络环境、应用系统以及当前的安全措施为基础,指出中国CDC安全建设需求与总体设计思路,结合国家等级保护的建设规范和技术要求,具体分析中国CDC等级安全技术体系与管理体系建设内容。     

公共卫生数据中心安全保障体系建设与思考

分析中国疾控中心数据中心信息化建设现状及信息安全保障体系存在的问题,对此提出总体应对框架,即构建以公共卫生业务系统为服务对象、安全管理体系建设为龙头、安全技术体系为基础的安全体系结构,为公共卫生数据中心信息安全保障体系建设提供借鉴。     

医院信息系统的应急建设与策略及安全管理

医院信息系统（HIS）的应急建设与应急策略对于HIS的安全保障十分重要。在系统应急建设方面,不仅应注重技术层面的建设,而且应注重管理层面的建设。本文结合实际工作提出了3种应急策略,并对每种策略进行了分析。HIS的安全管理有助于及时发现解决信息系统的安全隐患,从而降低系统出现大规模故障的风险。     

医院信息安全体系规划与设计

通过对医院信息安全内涵的深入研究,结合医院实际建设情况,分析医院信息安全存在的主要问题。将医院安全体系划分为物理层安全、网络层安全、系统层安全、应用层安全和安全管理等五个不同的层次,对各个不同层次进行安全需求分析。并在此基础上,从安全防护、安全临测、安全恢复三个层面对医院信息安全体系进行整体规划与设计。重点介绍几种安全技术在医院中的具体应用,包括：安全网闸技术在医院内网和外网上隔离的处理方式,数字签名技术在电子病历中的应用,时间戳技术在保障医疗信息时效性,安全性方面的应用等。     

医院无线网络系统实施方案的研究与应用

目的为医院网络建设提供多样、便捷、安全的组网方案。方法利用医院网络平台，引入无线局域网技术，对医院网络系统进行优化。结果无线网桥的应用保障了网络干线的安全，故障危害降至最低；移动医、护士工作站的运行，信息采集更加快捷，提高了工作效率。结论无线局域网技术在医院网络建设中具有较好应用效果。     

医院无线网络系统实施方柔的研究与应用

目的为医院网络建设提供多样、便捷、安全的组网方案。方法利用医院网络平台，引入无线局域网技术，对医院网络系统进行优化。结果无线网桥的应用保障了网络干线的安全，故障危害降至最低；移动医、护士工作站的运行，信息采集更加快捷，提高了工作效率。结论无线局域网技术在医院网络建设中具有较好应用效果。     

移动医疗数据安全策略研究

《药品监管网络安全与信息化建设“十四五”规划》明确指出，借助移动互联网技术，通过APP、公众号和小程序等多种方式推进监管业务和监管服务方式创新，实现国家、省、市、县各级药品监管部门在监管业务移动互联方面的协同发展。持续推进“中国药品监管”“化妆品监管”等重点移动应用建设，鼓励各级药品监管部门根据实际应用场景，创新服务内容，提升服务广度，逐步构建全方位、多维度的药品监管移动互联服务新格局。本研究针对数字化转型过程中移动应用数据面临的诸多安全挑战，以医疗行业移动应用为研究对象，以近年来国家针对移动应用数据安全实施的监管动作以及2021年《中华人民共和国数据安全法》明确的安全建设方向作为研究内容，探讨移动应用数据安全建设思路，提出建议思路：一是移动应用数据处理全生命周期进行技术能力建设，重点放在风险评估以及安全防护技术能力上；二是基于《中华人民共和国数据安全法》中数据保护方向进行安全体系建设，重点放在前端监测机制及应急响应能力建设上，以期搭建全面的移动应用数据安全策略。     

中医药项目绩效管理信息系统设计与实现

介绍中医药项目绩效管理信息系统建改目标,阐述基于安全套接层虚拟专用网通道和电子签章技术的系统架构、功能实现、安全设计及其应用,指出该系统有利于促进中医药项目绩效评价管理信息化建设。     

基于数字水印和数字签名技术的医学影像存储与传输系统安全机制研究

针对目前未引入安全机制的医学影像存储与传输系统，提出基于数字水印和数字签名技术的安全机制方案。数字水印技术对医学图像进行有效的版权等信息认证，数字签名技术对医学图像的发送方与接收方进行身份等信息的认证，为远程医疗的发展提供支持。     

医院管理系统中的信息安全探讨

随着计算机软件的发展,特别是分布式和软件移动计算的广泛应用,使得系统开放性越来越强,局域网内的用户都可能访问到应用系统和数据库,这给医院信息安全带来了极大的挑战。从收费数据到医疗信息、从病人隐私保密到管理信息的保密,都要求医院管理系统要处于高度安全的环境中。本文作者根据多年来从事医院管理信息系统和网络系统建设及维护工作的经验,从数据安全、服务器安全、机房安全、群集技术的可靠性、存储安全、网络安全、应用软件的安全和病毒防护等方面进行安全探讨。     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Dr.Zhang Ren''''s Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

Luo Lingjie''''s Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

猪肺磷脂注射液联合经鼻持续气道正压通气对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性的影响

目的 探讨猪肺磷脂注射液联合经鼻持续气道正压通气(NCPAP)对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性(CK-MB)的影响.方法 选取呼吸衰竭早产儿80例,分为观察组和对照组各40例.对照组采用NCPAP给氧治疗,观察组给予NCPAP给氧联合猪肺磷脂气管内给药.观察两组患儿治疗前及治疗12h、24 h后PaO2、PaCO2、血氧饱和度(SaO2)、pH的变化情况,检测治疗前及治疗5d后血清CK-MB水平;评估两组患儿的临床治疗效果.结果 两组患儿PaO2、PaCO2、SaO2、pH比较,差异均有统计学意义(P＜0.05),其中观察组治疗后的PaO2、SaO2、pH均高于对照组,PaCO2则低于对照组.两组的PaO2、SaO2、pH均随观察时间延长而升高(P＜0.05),PaCO2均随观察时间的延长而降低(P＜0.05).观察组治疗有效率为87.5％,显著高于对照组的70.0％ (P ＜0.05).治疗5d后两组患儿血清CK-MB水平均较前降低(P＜0.05),且观察组明显低于对照组(P＜0.05).结论 猪肺磷脂注射液气管内给药联合NCPAP可以显著降低呼吸衰竭早产儿CK-MB的含量,提高治疗有效率,起到很好的呼吸循环支持作用.     

Survey and practice of reporting quality of randomized controlled clinical trials on traditional Chinese medicine

Evidence obtained from randomized controlled trials （RCTs） has been generally accepted as the gold standard in the evaluation of clinical effectiveness. Readers need to understand the trial design, implementation, results, analysis and interpretation, so as to fully Jnderstand the results of RCTs. Thus, the investigators of RCTs have to report these items in a complete, accurate and clear manner. Since 1998, we have conducted several evaluations on the reporting quality of RCTs published in Chinese journals on traditional Chinese medicine （TCM） and results have shown that there is an urgent need for higher quality RCTs on TCM.     

TCM Treatment of Ankylosing Spondylitis by Tonifying the Kidney and Strengthening the Governor Vessel

Ankylosing spondylitis is a chronic and progressive disorder with inflammation mainly involving the central axis joints. It mainly affects the cervical spine and the lumbosacral area, with the pathogenesis closely related to the kidney and the Governor Vessel (GV). TCM holds that the syndrome is deficiency in origin and excess in superficiality, which is due to insufficiency of the kidney, deficiency of GV, and blocking of the channels with the invasion of exogenous evil, leading to poor circulation of qi and blood and malnutrition of the bones, muscles and joints. The TCM method of tonifying the kidney and strengthening GV to regulate circulation of qi and blood and check the arthralgia pain should be adopted, with the Kidney-Tonifying and GV Strengthening Decoction (益肾强督汤) prescribed.     

IMPROVING P-gp EXPRESSION IN HUMAN MONONUCLEAR CELLS IN VITRO TRANSFECTED BY MULTIDRUG RESISTANCE-1 mRNA

CHEMOTHERAPY playsa greatrolein the treat- ment of malignanttumors,especiallyingynecolo- gicalones.But inanticancerchemotherapy,leuko-cytopeniaisfrequentlytheprimarydose-limitingsideeffect factor.Moreover,cancersarefrequentlychemoresistantbe-causeof overexpressionof P-glycoprotein(P-gp), which isencodedby multidrugresistancegene (MDR1 ) and detectableinup to50% ofhuman cancersand renderscellsresistancetoanticancerdrugs.The safetyand potentialtherapeuticbenefitof mdr1 gene transferredto h…