解毒抗敏汤临床运用举隅

在多年治疗皮肤病的临床实践中,逐步总结出了一个疗效比较可靠、运用比较广泛、组方相对稳定的验方,取名解毒抗敏汤,运用解毒抗敏汤为基础方,结合辨证施治,治疗多种过敏性皮肤病,取得了较好的疗效。     

皮炎汤治疗血热型皮肤病的体会

皮炎汤是著名中医皮肤病学家朱仁康老中医的经验方，具有清热凉血、泄热化毒之功，笔者依据“异病同治”的原则，运用其治疗多种辨证属于血热内盛，发于肌肤的皮肤病，取得满意的疗效。     

"从血论治"角度探讨当归类方在皮肤病中的应用

血证之于皮肤病常从血热、血虚、血瘀论述,且多应用于银屑病的辨证论治之中,对于毒热内盛、寒邪客表等病机少有阐述。但临床辨证施治之时,诸多皮肤病症皆与“血”关系密切。本文通过简要介绍血证导致的常见皮肤病,并运用当归类方(当归芍药散、当归四逆汤、当归饮子、当归拈痛汤及四妙勇安汤)治疗皮肤病具有确切疗效予以佐证,以求加深从血论治在皮肤病辨证体系中的地位,为皮肤病临床治疗提供更多思路。     

张建荣教授运用经方治疗妇人病及验案举隅

张建荣教授对《金匮要略》妇人病有深入研究,临床擅长运用经方治妇人疾病,疗效满意;其临证运用经方较为灵活,特别注重辨证施治与随证加减、随机用药,不拘泥于成方成规。或经方合用,或经方加味,或经方加时方,笔者随师临证学习,对其运用温经汤、芎归胶艾汤、桂枝茯苓丸、肾气丸等方有所体会,并举案例3则,以供临床参考。     

运用经方体质学说治疗杂病验案举隅

黄煌经方体质学说有别于传统辨证思想,注重病体整体状态,总结出多种经方体质,该学说使经方应用更简明、有效,此文依据不同的经方体质特征,选用笔者8个运用黄连解毒汤、葛根汤合桂枝茯苓丸、大柴胡汤合半夏厚朴汤、炙甘草汤、柴胡桂枝干姜汤、桂枝茯苓丸、茯苓饮、温胆汤合除烦汤治疗内外妇各科疾病医案,并附录诊治体会。     

曾庆明运用柴胡加龙骨牡蛎汤治疗抑郁症经验

曾庆明教授认为抑郁症与肝、脾、肾三脏相关,与虚、痰、瘀、郁因素密切联系,多年临床经验运用柴胡加龙骨牡蛎汤辨证治疗抑郁症疗效显著,并且用药剂型上,善用汤剂开头,膏、丸、散、胶囊、酒剂殿后缓图其功。文章通过分析总结其运用柴胡加龙骨牡蛎汤治疗抑郁症方证机理和治疗抑郁症典型医案,证实柴胡加龙骨牡蛎汤治疗抑郁症有效性,分析其灵活辨证运用张仲景方的独特理论与具体用方经验,以期对中医临床运用柴胡加龙骨牡蛎汤有指导意义。     

何庆勇运用经方“行水八法”治疗心力衰竭经验

介绍何庆勇教授运用猪苓汤、五苓散、真武汤、防己黄芪汤、木防己汤、葶苈大枣泻肺汤、己椒苈黄丸、桂枝去芍药加麻黄细辛附子汤等经方,以"行水八法"治疗不同病因引起的心力衰竭的辨证思路与遣方用药。     

曾宪玉运用大柴胡汤治疗皮肤病经验举隅

大柴胡汤出自《伤寒杂病论》,是仲景名方,主少阳阳明合病。曾宪玉主任师从胡希恕经方学派大家,临床基于六经辨证运用大柴胡汤治疗多种皮肤病疗效良好。现将曾师关于大柴胡汤的临床应用经验介绍如下。1辨证要点与应用原则大柴胡汤出自《伤寒杂病论》,由小柴胡汤去党参、甘草加枳实、大黄、芍药而成,是少阳阳明合病的主方[1]。皮肤科疾病病种繁多,病机复杂,多数疾病在发病过程中都会呈现出少阳阳明合病的特点,用于皮肤病治疗大有裨益。     

从三阴病论治慢性荨麻疹体会

从三阴病角度探讨慢性荨麻疹的治疗，认为病情反复发作，免疫功能低下者多见于三阴症，方讧结合，谨守病机；并认为六经皆有表证，是六经辨证治疗皮肤病的基础。     

高益民教授临床应用秦艽丸经验

<正>高益民,首都医科大学中医药学院教授、主任医师、国家级名老中医,从事中医、中西医结合临床50余年,擅长内、外、妇科疑难杂症的诊治。高益民教授临床上传承了北京著名皮外科泰斗赵炳南先生的学术经验,高老临床上善于运用秦艽丸加减治疗银屑病、神经性皮炎、系统性红斑狼疮等疾病,多获良效,认为秦艽丸具有祛风、清热、解毒、燥湿、化瘀等功效,适用于具有"风""湿""热""毒""瘀"等病机特点的皮肤病的治疗。对于临床反复发作,迁延不愈,瘙     

微波消解-电感耦合等离子体质谱法测定脉络宁注射液中25种矿物质元素

目的建立微波消解-电感耦合等离子体质谱(ICP-MS)直接稀释测定脉络宁注射液中25种矿物质元素(Mg、Ca、Fe、Cu、Zn、Mn、Al、B、Ba、Co、Cr、K、Li、Mo、Na、Ni、P、Pb、Sr、Th、Ti、V、As、Cd和Hg)的方法。方法分别对微波消解条件和测试条件进行考察;样品经微波消解后,采用电感耦合质谱仪测定25种矿物质元素,并对测定方法学进行考察。结果确定最佳消解条件为3步缓慢升温:400 W 80℃升温10 min,保留5 min;600 W 120℃升温10 min,保留5 min;900 W 200℃升温20 min,保留20 min;25种矿物质元素在各自的线性范围内线性关系良好,r≥0.999 6,精密度、稳定性和重复性试验的RSD均符合定量分析要求;加标回收率为94.7%~106.1%,RSD在0.34%~2.79%。脉络宁注射液中检测出Mg、Ca、Fe、Cu、Zn、Mn、Al、B、Ba、Co、Cr、K、Li、Mo、Na、Ni、P、Pb、Sr、Th、Ti、V,未检出As、Cd和Hg。结论该方法简便、迅速、准确,适用于脉络宁注射液中25种矿物质元素的同时测定。     

Die Lateralität und Lateralitätsinstabilität in der Diagnostik und Therapie

The disturbance and instability of laterality are obstacles to diagnostics and therapy. Correction prior to starting therapy is required. They also predispose toward defined health problems and unspecific diseases. Numerous research activities provide evidence of the relevance of undisturbed laterality in diagnostics and therapy. Techniques of testing and therapeutic corrections will allow for optimized therapy success.     

Journal of Acupuncture and Tuina Science Instructions for Authors

The Journal of Acupuncture and Tuina Science, a journal with an international scope （IS SN 1672-3597, CN 31-1908/R, Bimonthly）, is embodied by ＇Springer Verlag＇ Database, Index Copernicus （IC） and Chinese Scientific and Technical Paper and Citations Data （CSTPCD）. You can search full text on http：//www, springerlink, com/content/1672 -3597.     

Yerba Mate or Paraguay Tea

正Beverages based on Ilex paraguariensis A.St.-Hil.are used in the south Brazil and other Latin American countries located at the so-called southern cone.It is known as chimarro or mate in south and southeast Brazil,tererêin     

Ethnopharmacologic study of chinese rhubarb

This paper deals with an interdisciplinary study covering historic, botanical, phytochemical, pharmacological and clinical aspects of rhubarb and related species, to lay stress on the correlation between plant phylogeny, chemical constituents and purgative activity.

It was found that the official rhubarbs were exclusively restricted in the Sect. Palmata e.g. Rheum palmatum R. palmatum var. tanguticum R. officinale; the following criteria may serve as their standard, viz., the presence of sennoside derivatives and rhein, the occurrence of the reduced form of rhein and aloe-emodin, the leaves with any kind of palmate incision. Comprehensive multivariate analyses showed that there is a very close relationship between the leaf incision, existence of sennosides or rhein and purgative activity.     

Wirksamkeit der Akupunktur bei der Therapie von idiopathischen Schmeckstörungen: Eine randomisierte Placebo-kontrollierte Studie

Background

At present, the state-of-the-art medication in treating idiopathic taste disorder (gustatory dysfunction) is zinc. If zinc medication was unsuccessful, not tolerated or if it is contraindicated the persons affected can hardly be helped.

Objectives

In a randomized placebo-controlled clinical trial an attempt was made to determine the efficacy of acupuncture.

Methods

The treatment group was treated with acupuncture needles, the placebo group with an inactive acupuncture-laser. Endpoints of the study were changes in the taste test, the quality of life and the severity of symptoms of depression (BDI) as well as mood changes (ZMS). Satisfaction with the success of the respective therapy was also evaluated. Data were collected before and after therapy and again for the treatment group 10 weeks after completion of the treatment period.

Findings

Treatment with real acupuncture showed a significant improvement in gustatory function as well as a significant improvement in psychological symptoms. Greater satisfaction with the treatment results was evident in the treatment group. The treatment results of acupuncture remained stable over a period of ten weeks after completion of the treatment.

Conclusion

Acupuncture was effective in the therapy of idiopathic taste disorders and therefore it is an effective alternative when zinc medication is not tolerated or unsuccessful. But it is also suitable as a therapy of first choice. Acupuncture can be considered as an extension of the therapeutic spectrum in the difficult treatment of taste disorders.     

Veränderungen der Herzratenvariabilität (HRV) während Low Level Lasernadelakupunktur: Placebokontrollierte Studie an 19 herzgesunden Probanden

Background

Experimental and clinical studies postulate a neurobiological mechanism of acupuncture by modulating central pain systems, neurohormones and -transmitters. It seems to be quite likely that the autonomic nervous system (ANS) plays an important mediating role in this neuromodulation.

Aim

In measuring heart rate variability (HRV), as a non-invasive approach to the ANS-function, the object of this study was to monitor probable acupuncture-induced changes of autonomic balance. The innovative technology of laser-needle acupuncture offers for the first time a stimulation method which fulfils the demands on a placebo-controlled acupuncture trial not requiring controversial sham acupuncture.

Method

19 healthy voluntary subjects underwent 3 treatments in randomized sequence, consisting of placebo-, 1-point- (PC 6) and simultaneous 3-point- (PC 6, LR 3, SI 3) laser-needle-stimulation over 20 minutes. Before, during and after placebo-/verum laser-needle acupuncture, HRV-data for normalized HF(high frequency)- and LF(low frequency)-Power (nHF, nLF) and their quotient nLF/nHF obtained by power spectrum analysis (FFT), were measured and analyzed statistically at 5 different time points (ANOVA repeated measures, p < 0,05).

Results

During both verum applications, the 1-point- (PC 6) as well as the simultaneous 3-point- (PC 6, LR 3, SI 3) laser-needle stimulation, significant changes of the ANS-activity were found in comparison to the placebo application. The most significant modification of HRV was an increase of nHF (p < 0,05 (PC 6), p < 0,0001 (PC 6, LR 3, SI 3)) as an expression of growing vagal activity during acupuncture.

Conclusion

Laser-needle acupuncture causes in 1-point-stimulation (PC 6) as well as in simultaneous 3-point-stimulation (PC 6, LR 3, SI 3) significant changes in HRV in comparison to placebo application. HRV-monitoring seems to be a suitable approach in exploration of acupuncture-induced changes of ANS and could possibly be established in combination with laser needle acupuncture as a standard for further scientific and clinical acupuncture investigations which are greatly needed.     

瑞香科五属植物中酚性聚合物的结构特征、分布及药理活性研究进展

瑞香科植物广泛分布于世界热带和温带地区,其中多种植物可供药用。在对该科植物的研究中发现,黄酮类、木脂素和香豆素等酚性化合物的低聚体为其重要的特征性成分,药理活性主要表现在抗肿瘤、抗炎、抗氧化、抗菌和抗病毒等方面。对已发现的酚性聚合体的化学结构、植物来源及药理活性进行综述,为瑞香科植物今后的研究和开发利用提供参考。     

HPLC法同时测定沉香化滞丸中11种成分

目的采用HPLC梯度洗脱法同时测定沉香化滞丸中沉香四醇、柚皮苷、橙皮苷、新橙皮苷、和厚朴酚、大黄素、厚朴酚、木香烃内酯、去氢木香内酯、大黄酚、大黄素甲醚11种成分。方法采用Thermo Syncronis C18色谱柱(250 mm×4.6 mm,5μm),流动相为水-乙腈,梯度洗脱:0～10 min,20%乙腈;10～20 min,20%～40%乙腈;20～24 min,40%乙腈;24～26 min,40%～52%乙腈;26～30 min,52%乙腈;30～31 min,52%～90%乙腈;31～35 min,90%乙腈;35～40 min,90%～100%乙腈;40～43min,100%乙腈;43～45min,100%～20%乙腈;检测波长215nm,体积流量1.0m L/min,柱温30℃,进样量20μL。结果各成分在43 min内分离良好,沉香四醇、柚皮苷、橙皮苷、新橙皮苷、和厚朴酚、大黄素、厚朴酚、木香烃内酯、去氢木香内酯、大黄酚、大黄素甲醚的线性范围分别为1.4～13.6、10.0～200.0、31.5～315.0、1.0～120.1、1.8～50.6、0.93～10.1、1.8～30.0、0.2～40.3、1.8～18.1、1.7～25.0、0.45～10.70μg/mL;样品中各成分的平均回收率均在98.90%～100.87%;11种成分精密度RSD在0.55%～1.54%;供试品溶液在30 h内稳定性良好,RSD在0.75%～1.94%;重复性RSD在0.39%～1.73%。6批次样品中沉香四醇、柚皮苷、橙皮苷、新橙皮苷、和厚朴酚、大黄素、厚朴酚、木香烃内酯、去氢木香内酯、大黄酚、大黄素甲醚质量分数分别为92.0～201.0、511.5～9 033.0、5 475.0～12 635.5、54.5～5 095.5、192.0～2 137.5、117.0～391.5、106.5～1 281.5、13.0～136.5、93.5～199.0、177.0～1 207.0、33.5～251.5μg/g。结论本方法准确、快速、简便,重复性好,精密度高,适用于沉香化滞丸中多种活性成分的定量分析。