卵巢Brenner瘤的影像学表现及病理对照分析

目的 探讨卵巢Brenner瘤的影像特点及其与病理的关系。方法 回顾性分析12例经手术病理证实的卵巢Brenner瘤患者的影像表现,并与临床病理资料对照分析。结果 单侧病变9例,双侧病变3例。实性病变5例,均为良性,瘤体内伴大量无定形钙化,增强扫描呈轻或中度持续强化。囊实性病变6例,4例为交界性Brenner瘤,2例为混合型肿瘤（交界性Brenner瘤合并黏液性囊腺瘤）;5例以囊性为主,可见壁结节,1例以实性为主。各例实性部分均可见钙化,增强扫描呈中度或明显持续渐进性强化。另有1例双侧交界性Brenner瘤表现为一侧实性、一侧囊实性合并黏液性囊腺瘤。实性病变和囊实性病变实性部分T2WI呈低信号。结论 卵巢Brenner瘤的CT表现具有较高特异性,MRI表现具有一定特点。     

卵泡膜细胞瘤的CT及MRI表现(附24例分析)

目的:探讨分析卵巢纤维卵泡膜细胞瘤的影像学特征。材料与方法:回顾性分析经病理证实的24例卵巢纤维卵泡膜细胞瘤的临床、影像学资料,重点分析患者年龄、病变部位、病灶大小CT特点及MRI信号特征。结果:24例患者中,共27个病灶,发病平均年龄55岁,11例左侧,10例右侧,3例双侧发病,肿块最大径2.9-20.0cm,平均值9.9cm,病灶实性为主22例,囊性为主5例。瘤内伴出血2例,钙化2例,瘤内小囊变2例。CT扫描多数形态规则,边界清楚,平扫等密度,囊变低密度,伴出血高密度。MRI实性部分T1WI等信号,T2WI稍高信号,内可见囊变信号。结论:纤维卵泡膜细胞瘤多发生于绝经期女性,单侧发病多见,偶有双侧。需依据病理明确诊断,CT及MRI表现具有一定的特征性,手术切除预后较好。     

卵巢Brenner瘤的超声诊断研究

目的探讨卵巢Brenner瘤(勃勒纳瘤)的超声诊断特征。方法回顾性分析在我院超声检查并经手术及病理证实的32例卵巢Brenner瘤患者的超声图像,并与病理结果对照。结果 32例卵巢Brenner瘤中病理结果为良性的20例、交界性7例、恶性5例。20例良性中有14例为实性包块,6例为囊实性包块;7例交界性中2例为实性包块,5例为囊实性包块,恶性均表现为以囊性为主的囊实性包块。良性及交界性卵巢Brenner瘤实性部分内均可见多形性钙化,后方可见扇形声影,恶性其内可见厚薄不等的分隔。良性卵巢Brenner瘤血流信号不丰富,交界性卵巢Brenner瘤血流信号较丰富。结论超声检查中发现卵巢实性或囊实性包块伴有多形性钙化,后方伴扇形声影,提示包块为Brenner瘤的可能性很大。CDFI对于区分良性、交界性Brenner瘤具有一定的参考意义。     

卵巢Brenner瘤15例超声表现分析

目的：探讨超声在卵巢Brenner瘤中的诊断价值 方法：回顾性分析2014年1月至2018年11月期间武汉大学人民医院妇产科诊断为卵巢Brenner瘤的15例病例,分析其超声表现及彩色多普勒血流特点。 结果：15例卵巢Brenner瘤患者中,良性12例,恶性1例,交界性2例。12例良性者,表现为实性者5例,其中4例肿瘤内可见强回声钙化,后伴声影,1例肿瘤内未见钙化,表现为囊性者2例,内均未见钙化,1例良性者合并粘液性囊腺瘤,肿瘤呈囊性,未见钙化,余4例超声检查未见病灶,仅在显微镜下发现Brenner瘤病灶。2例交界性者,1例表现为囊性,未见钙化,1例表现为囊实性,可见钙化。1例恶性者表现为囊实性,内可钙化。彩色多普勒显示良性、交界性、恶性卵巢Brenner瘤内均表现为无血流或少许血流信号,三者间无明显差异。 结论：卵巢Brenner瘤可表现为实性、囊性或囊实性包块,良性者多表现为实性,恶性者多表现为囊实性,交界性者可表现为囊性或囊实性,混合其他肿瘤者声像图表现更加复杂。无论良性、交界性、恶性,肿瘤内均可出现钙化,彩色多普勒对三者之间的鉴别意义有限。     

卵巢畸胎瘤的CT诊断

目的:探讨卵巢畸胎瘤的CT表现及特征。方法:回顾性分析11例经临床病理证实的卵巢畸胎瘤的CT表现,11例病人均作CT平扫及增强扫描。结果:5例囊性,4例囊实性,2例实性。1例有骨骼样密度影,3例有牙齿状钙化影,7例有脂肪样密度影,3例有毛发团样密度影。结论:卵巢瘤的CT特征性表现为:①肿块中含有脂肪、骨骼或齿状钙化密度影。②肿块中出现脂-液平面征像。③囊性肿块中可见弧形钙化,液样密度中可见实性组织及球形钙化。卵巢肿块有上叙特征之一,即可诊断为畸胎瘤,当没有上叙特征性CT表现时,应与卵巢囊腺瘤、卵巢囊肿等鉴别。     

多层螺旋CT对女性盆腔囊性病变的鉴别诊断

目的提高多层螺旋CT诊断女性盆腔囊性肿块的正确性。方法收集明确诊断的女性盆腔囊性肿块84例共102个病灶，所有病例行多层螺旋CT平扫、增强扫描及多平面重建，并对其CT表现作回顾性分析。结果102个囊性包块，良性86个，恶性16个。CT诊断定位正确80例（96．1％），定性正确69例（82．1％）。其中卵巢囊性畸胎瘤13例13个病灶；卵巢囊腺瘤11例15个病灶；卵巢囊腺癌5例9个病灶；卵巢转移瘤3例4个病灶；卵巢内膜异位囊肿12例16个病灶；卵巢囊肿19例22个病灶；输卵管积水或积脓5例7个病灶；子宫内膜癌3例；盆腔囊性感染性包块8例；其它5例。结论多层螺旋CT对女性盆腔囊性肿块定位及定性诊断具有较高价值。     

Krukenberg瘤的磁共振诊断

目的:比较Krukenberg瘤与原发性卵巢肿瘤的MRI特点,探讨Krukenberg瘤的影像学特征。方法:回顾性分析经手术病理证实的24例Krukenberg瘤和60例原发性卵巢肿瘤的MRI表现。依据MRI信号将肿瘤分为3型:实性为主型、囊实性及囊性为主型。结果:24个Krukenberg瘤患者共发现39个病灶,发生于双侧卵巢15例、单侧9例。39个病灶中,实性为主型20个、囊实性11个、囊性为主型8个;增强后病灶实性成分和(或)囊壁明显强化。60例卵巢原发肿瘤患者共发现87个病灶,发生于双侧卵巢27例、单侧33例。87个病灶中,16个实性为主,19个囊实性,52个囊性为主。19个囊实性肿块增强后有4个(4/19,21.0%)囊肿壁明显强化。结论:当双侧卵巢出现实性或囊实性肿块,尤其肿块中囊肿壁出现明显强化时,应考虑Krukenberg瘤的可能。     

儿童卵巢卵黄囊瘤的临床表现、超声及CT对照分析

目的：通过对儿童卵巢卵黄囊瘤的临床表现、超声及CT特征分析，提高对儿童该病的认识和诊断率。方法：收集我院2014—2021年经病理确诊的13例儿童卵巢卵黄囊瘤患者资料，通过对该13例患儿卵巢卵黄囊瘤的二维超声特点、彩色多普勒及能量多普勒血流半定量分级、CT平扫及增强扫描并结合临床表现和实验室检查结果综合回顾分析。结果：13例患儿年龄最大的14岁，最小的1岁，5例（38%）以腹痛就诊，7例（54%）以腹部肿块就诊，1例（8%）以尿频就诊。超声提示13例患儿的肿块均位于盆腔或下腹部，9例（69%）病灶以实性为主的实性病变，4例（31%）病灶以囊性为主的囊实性病变，Adler血流分级均在Ⅱ～Ⅲ级。CT平扫显示为下腹部或盆腔圆形或类圆形等、低密度的囊实性肿块，CT增强扫描显示为盆、腹腔渐进性不均匀增强的囊实性肿块，部分可见点状或线状血管影。13例患儿甲胎蛋白升高，均>1 210 ng/mL。结论：儿童卵巢卵黄囊瘤常见的临床表现为腹痛和腹部肿块，当超声或CT检查发现女童盆腔或下腹部囊实性占位并伴随甲胎蛋白升高时可优先考虑为卵巢卵黄囊瘤。     

原发性卵黄囊瘤CT诊断及相关文献分析（附10例报告）

目的：探讨CT对原发性卵黄囊瘤的诊断价值。方法：回顾性分析我院近十年10例经手术、病理证实的卵黄囊瘤的CT表现。结果：10例发病部位为肝1例、睾丸4例,卵巢5例。CT表现：8例＞5 cm,7例边界较清,8例囊实性肿块,7例伴有壁结节,出血及钙化各1例,10例增强实性部分逐渐强化,8例有转移。结论：卵黄囊瘤是一种罕见且恶性程度非常高的生殖细胞肿瘤,CT在卵黄囊瘤的早期诊断中有重要的价值。     

肾上腺节细胞神经瘤的CT诊断

目的：探讨肾上腺节细胞神经瘤的CT表现特征,以提高正确诊断率。方法回顾性分析经手术病理证实的6例肾上腺节细胞神经瘤的临床及CT表现,并与手术及病理结果行对照研究。结果6例肾上腺节细胞神经瘤均为单发病灶。CT平扫1例呈单囊性病灶,5例为实性,CT值20～42 HU,密度欠均匀,其中1例伴有点状钙化。肿瘤直径2.3～16.8 cm,平均5.4 cm。6例肿块呈椭圆形,边界均显示清楚,2例边缘稍不规则。增强扫描1例动脉期及静脉期见分隔样强化,3例延迟扫描见轻度强化。病理检查5例实性病灶表现为增生的神经纤维细胞、少量的成熟神经节细胞和间质血管增生,1例囊性病灶内可见大量黏液基质。结论肾上腺节细胞神经瘤CT表现具有一定特征,正确认识其影像学表现,有助于提高诊断率并减少误诊。     

Brenner tumors of the ovary: sonographic and computed tomographic imaging features.

OBJECTIVE: The purpose of this study was to describe the sonographic appearance of ovarian Brenner tumors with computed tomographic (CT) correlation. METHODS: Twenty-two female patients (age range, 32-78 years; mean, 58 years) with 25 ovarian Brenner tumors were identified from pathologic records from 1990 to 2005. Corresponding pathologic reports and images (17 sonographic and 14 CT) were reviewed independently. RESULTS: Tumors ranged in size from 0.3 to 12 cm (mean, 2.5 cm); all were benign. Sixteen (64%) of 25 were found incidentally. Eight (36%) of 22 patients had a total of 12 associated benign ovarian neoplasms (1 was contralateral); 3 patients had bilateral Brenner tumors. Eight (47%) of 17 tumors were not seen on sonography, and 5 (36%) of 14 were not seen on CT. Of the tumors seen on imaging, most were solid (67% on sonography and 78% on CT). Four tumors appeared at least partially cystic, of which 3 had coexistent cystic ovarian lesions. CONCLUSIONS: Brenner tumors are most often solid neoplasms found incidentally and frequently seen in association with other benign ovarian epithelial neoplasms.     

Sonographic features of Brenner tumor of the ovary

The sonographic findings in four patients with benign Brenner tumors of the ovary are described. Computed tomography (CT) was also obtained in one case. The neoplasms were solid, hypoechoic masses, usually exhibiting good through transmission of sound. Two neoplasms contained peripheral calcifications; one was inseparable from the uterus and was misdiagnosed as a leiomyoma; the other was well-demonstrated by CT but only in retrospect was the peripherally located calcification identified. Sonographically, Brenner tumors are similar to other solid ovarian neoplasms, particularly fibromas-thecomas, and can also be confused with pedunculated leiomyomas.     

CT findings in metastatic ovarian tumors from gastrointestinal tract neoplasms (Krukenberg tumors)

The computed tomographic (CT) findings are reviewed in 7 patients with metastatic ovarian tumors from gastrointestinal tract neoplasms (Krukenberg tumors). All patients presented mixed ovarian masses. In 6 cases the masses were mainly cystic, with internal septa and focal or uniform enlargement of the cyst wall. In the seventh patient the ovarian mass appeared on the CT as mainly solid. The size of the neoplasm varied between 5 and 46 cm. Ascites was only seen in 1 case and in another the existence of a primary tumor in the sigmoid colon was demonstrated. In our cases the CT signs of ovarian metastasis were indistinguishable from primary tumors of the ovary.     

Ovarian mucinous cystadenoma coexisting with benign Brenner tumor: MR imaging findings

Purpose

The purpose of this study was to describe the MR imaging findings of ovarian mucinous cystadenomas coexisting with benign Brenner tumors.

Materials and methods

MR images with a 1.5-T unit obtained in five consecutive patients (age range, 51–72 years; mean age, 61 years) with surgically confirmed ovarian mucinous cystadenomas coexisting with benign Brenner tumors were retrospectively reviewed for the presence, configuration, and signal intensity of cystic and solid components of the lesions.

Results

Tumors ranged in size from 7.5 to 22.1 cm (mean, 13.5 cm). In four patients (80%), the size of mucinous cystadenoma (range 6.4–22.1 cm; mean, 12.5 cm) was larger than that of Brenner tumor (range 0.2–9.1 cm; mean, 2.8 cm). All patients (100%) had cystic, and three (60%) had solid components. Four patients (80%) showed multilocular cystic, and one (20%) showed unilocular cystic appearance. MR imaging findings were classified into three patterns: (1) a bulky solid mass adjacent to the cystic component, (2) a mural nodule at the periphery of the cystic component, and (3) a cystic component without a detectable solid component. All four multilocular cystic areas exhibited “stained glass” appearances on both T1- and T2-weighted images, and all three solid areas showed homogeneous hypointensity on T2-weighted images.

Conclusion

Mucinous cystadenomas were often larger than the coexisting benign Brenner tumors. Mucinous cystadenomas coexisting with benign Brenner tumors should be considered when multilocular or unilocular cystic components are accompanied by homogeneously hypointense solid components on T2-weighted images.     

卵巢Brenner瘤的超声病理对照研究

目的 探讨卵巢Brenner瘤的超声图像特征，并与病理改变对照分析。方法 经腹与经阴道超声检查结合，观察卵巢Brenner瘤9例；全部病例经手术及病理证实。结果 Brenner瘤超声表现为：瘤体呈“蛋壳”征，后方有明显的声衰减；肿块边界清晰的不均质低回声或部分低回声病灶。4例经CDFI检查，1例恶性瘤体内探及较多血流信号，其余3例良性者瘤内均未探及明显血流信号。结论 卵巢Brenner瘤的超声表现具有一定特征。CDFI可能有利于良恶性Brenner瘤的鉴别诊断。     

子宫及其附件区巨大实性肿块的影像学分析

目的探讨原发性子宫及附件区巨大实性肿块的CT、MRI表现及其诊断价值。方法回顾性分析17例患者共18个经手术病理证实的原发性子宫及附件区巨大实性肿块的影像学及临床资料。结果 17例中,巨大外突性浆膜下子宫肌瘤5例;原发性输卵管癌1例;卵巢肿瘤11例,其中畸胎瘤、纤维卵泡膜瘤、卵巢内膜样癌各3例,颗粒细胞瘤、Brenner瘤各1例。结论 CT和MRI能清晰显示病变内脂肪、钙化及盆腔积液、桥血管征,增强扫描有助于定位及定性诊断原发性子宫及其附件区巨大实性肿块。     

恶性卵巢子宫内膜样肿瘤的影像学评价

目的探讨恶性卵巢子宫内膜样肿瘤的CT及MRI诊断价值。方法回顾性分析10例经手术病理证实的恶性卵巢子宫内膜样肿瘤的cT或MRI表现。结果10例恶性卵巢子宫内膜样肿瘤13个肿块．7例为单侧（左侧4例,右侧3例）,3例为双侧（左右各一）。10例中卵巢子宫内膜样腺癌7例;恶性Maller混合瘤2例（1例为双侧,1例合并子宫内膜腺癌）;卵巢子宫内膜样间质肉瘤合并子宫内膜异位症1例。平扫示肿瘤多为类圆形、分叶状实性为主肿块,囊变多见,增强扫描后肿瘤实性部分不均匀强化,部分病例边缘明显强化,呈多囊状环形强化6例。结论恶性卵巢子宫内膜样肿瘤的影像表现具有一定特征性,CT和／或MR可明确定性,对病理诊断有一定的提示作用。     

肾上腺髓样脂肪瘤的CT表现

目的 分析肾上腺髓样脂肪瘤的CT表现,提高CT诊断的准确性。方法 本文报道螺旋CT检出的7例肾上腺髓样脂肪瘤并分析其CT征象,包括男性1例,女6例,年龄30-76岁,平均56岁。其中5例肿瘤起源于右侧肾上腺,1例起源于左侧肾上腺,另外1例为双恻性髓样脂肪瘤。结果 CT检查显示所有病例均起源于肾上腺并检出瘤体内脂肪成分,所有瘤体均位于肾上腺内外侧肢夹角的后方。肿瘤中6个以脂肪成分为主,2个以软组织成分为主：3个肿瘤中见点状钙化;2个以软组织成分为主的肿瘤可见完整的包膜,而6个以脂肪成分为主的肿瘤根据CT图象未能显示肿瘤包膜。在3例患者的对侧正常肾上腺周围可见大量脂肪。结论 螺旋CT薄层扫描可提供肾上腺髓样脂肪瘤详细解剖细节,有较高的诊断正确性。     

Virilizing tumors of the ovary: imaging features.

AIM: Virilizing tumors of the ovary are an uncommon cause of a common clinical problem. The reported imaging features of these tumors are based on case reports. The purpose of this study was to determine the spectrum of imaging characteristics of these tumors based on a larger referral population. PATIENTS AND METHODS: Case records from the Armed Forces Institute of Pathology were searched for clinical evidence of virilization as a presentation of an excised sex cord-stromal and steroid cell ovarian tumor. Records and imaging studies on 14 patients with virilizing tumors were found. All available imaging studies (ultrasound studies of the pelvis (11 patients), CT scans of the pelvis (five patients), MRI examinations of the pelvis (two patients), and plain films of the pelvis (four patients) were reviewed by three radiologists independently for ascites, calcification, percent solid portion, echogenicity and attenuation. RESULTS: On CT and/or ultrasound most (69%) of the tumors appeared to be solid or mostly solid. The amount of solid tissue varied with the tumor type, granulosa cell tumors were predominantly cystic. The masses were isoechoic (82%) or hypoechoic (18%). Ascites was an infrequent (23%) finding. Only a minority of these tumors (14%) were calcified on imaging studies. Six tumors were 5.0 cm or less in mean size, and two less than 3.0 cm in size. All cases were stage I tumors at presentation. CONCLUSION: The majority of virilizing tumors of the ovary are typically solid, noncalcified, confined to the ovary at presentation, and not associated with ascites. Variability in appearance depends in part on tumor type. Many are small and may be difficult to recognize as a mass morphologically.