N1-methyladenosine formation,gene regulation,biological functions,and clinical relevance

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Impacts and mechanisms of alternative mRNA splicing in cancer metabolism,immune response,and therapeutics

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Targeted therapy for rare lung cancers: Status,challenges, and prospects

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Personalized Cancer Vaccines: Clinical Landscape,Challenges, and Opportunities

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Downregulation of a mitochondrial micropeptide,MPM, promotes hepatoma metastasis by enhancing mitochondrial complex I activity

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Immunodepletion of MDSC by AMV564, a novel bivalent,bispecific CD33/CD3 T cell engager,ex vivo in MDS and melanoma

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Safety,Tumor Reduction,and Clinical Impact of Zika Virus Injection in Dogs with Advanced-Stage Brain Tumors

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Anti-atherosclerotic therapies: Milestones,challenges, and emerging innovations

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An Endogenous Anti-aging Factor,Sonic Hedgehog,Suppresses Endometrial Stem Cell Aging through SERPINB2

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Durable immunogenicity,adaptation to emerging variants,and low-dose efficacy of an AAV-based COVID-19 vaccine platform in macaques

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Oncolytic Adenovirus Armed with BiTE,Cytokine, and Checkpoint Inhibitor Enables CAR T Cells to Control the Growth of Heterogeneous Tumors

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COVID-eVax,an electroporated DNA vaccine candidate encoding the SARS-CoV-2 RBD,elicits protective responses in animal models

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miR-1293, a Candidate for miRNA-Based Cancer Therapeutics,Simultaneously Targets BRD4 and the DNA Repair Pathway

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WNT-modulating gene silencers as a gene therapy for osteoporosis,bone fracture,and critical-sized bone defects

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Association of Pericardial Fat with Cardiac Structure,Function, and Mechanics: The Multi-Ethnic Study of Atherosclerosis

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Corticosteroids and cellulose purification improve,respectively, the in vivo translation and vaccination efficacy of sa-mRNAs

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Sonic Hedgehog,a Novel Endogenous Damage Signal,Activates Multiple Beneficial Functions of Human Endometrial Stem Cells

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Clinical,Experimental, and Computational Validation of a New Doppler-Based Index for Coarctation Severity Assessment

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Lyophilization provides long-term stability for a lipid nanoparticle-formulated,nucleoside-modified mRNA vaccine

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A Multi-Targeting,Nucleoside-Modified mRNA Influenza Virus Vaccine Provides Broad Protection in Mice

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