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Lyophilization provides long-term stability for a lipid nanoparticle-formulated,nucleoside-modified mRNA vaccine
Institution:1. Department of Microbiology, University of Pennsylvania, Philadelphia, PA 19104, USA;2. Genevant Sciences Corporation, Vancouver, BC V5T 4T5, Canada;3. Biotechnological National Laboratory, Institute of Genetics, Biological Research Centre, Szeged 6726, Hungary;4. Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA;5. BioNTech RNA Pharmaceuticals, Mainz 55131, Germany
Abstract:
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  • Keywords:mRNA  lipid nanoparticle  nucleoside modification  lyophilization  vaccine
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