The role of the mitochondrial protein VDAC1 in inflammatory bowel disease: a potential therapeutic target

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Mitochondrial micropeptide STMP1 promotes G1/S transition by enhancing mitochondrial complex IV activity

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Cardiolipin remodeling by ALCAT1 links hypoxia to coronary artery disease by promoting mitochondrial dysfunction

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Targeted therapy for rare lung cancers: Status,challenges, and prospects

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An Endogenous Anti-aging Factor,Sonic Hedgehog,Suppresses Endometrial Stem Cell Aging through SERPINB2

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N1-methyladenosine formation,gene regulation,biological functions,and clinical relevance

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COVID-eVax,an electroporated DNA vaccine candidate encoding the SARS-CoV-2 RBD,elicits protective responses in animal models

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miR-1293, a Candidate for miRNA-Based Cancer Therapeutics,Simultaneously Targets BRD4 and the DNA Repair Pathway

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Impacts and mechanisms of alternative mRNA splicing in cancer metabolism,immune response,and therapeutics

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Personalized Cancer Vaccines: Clinical Landscape,Challenges, and Opportunities

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Tryptophanyl-tRNA Synthetase,a Novel Damage-Induced Cytokine,Significantly Increases the Therapeutic Effects of Endometrial Stem Cells

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Immunodepletion of MDSC by AMV564, a novel bivalent,bispecific CD33/CD3 T cell engager,ex vivo in MDS and melanoma

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Safety,Tumor Reduction,and Clinical Impact of Zika Virus Injection in Dogs with Advanced-Stage Brain Tumors

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Durable immunogenicity,adaptation to emerging variants,and low-dose efficacy of an AAV-based COVID-19 vaccine platform in macaques

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Oncolytic Adenovirus Armed with BiTE,Cytokine, and Checkpoint Inhibitor Enables CAR T Cells to Control the Growth of Heterogeneous Tumors

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Non-invasive Reporter Gene Imaging of Cell Therapies,including T Cells and Stem Cells

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Mutation-Independent Allele-Specific Editing by CRISPR-Cas9, a Novel Approach to Treat Autosomal Dominant Disease

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Tracking human neurologic disease status in mouse brain/plasma using reporter-tagged,EV-associated biomarkers

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Single-Cell Transcriptome Analysis Reveals Intratumoral Heterogeneity in ccRCC,which Results in Different Clinical Outcomes

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WNT-modulating gene silencers as a gene therapy for osteoporosis,bone fracture,and critical-sized bone defects

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