精索旁侵袭性血管黏液瘤的临床特征(附2例报告及复习文献)

目的探讨精索旁侵袭性血管黏液瘤的临床特征。方法报告2例精索旁侵袭性血管黏液瘤患者的临床资料,结合文献复习进行讨论。结果2例患者的精索旁侵袭性血管黏液瘤均手术完整切除,经随访6~8个月,无肿瘤复发。病理诊断为精索旁侵袭性血管黏液瘤。结论侵袭性血管黏液瘤临床罕见,在男性好发于精索旁,确诊依赖病理学检查,治疗需手术完整切除肿瘤,术后应长期严密随访。     

罕见的胫骨侵袭性纤维瘤1例报告

侵袭性纤维瘤又称韧带样纤维瘤、硬纤维瘤,是一种来源于纤维组织的罕见肿瘤,其发病率占软组织肿瘤的0.03%,占纤维组织肿瘤的1.19%.该病在病理上为良性表现,临床上却具有侵袭性生长和极易复发的特性,但不发生转移.最常见于青年人的肩胛带、胸部及臀部,发生在胫骨的较为少见.现将我科收治的1例罕见的胫骨侵袭性纤维瘤报道如下.     

男性直肠侵袭性血管黏液瘤1例报告

侵袭性血管黏液瘤(aggressive angiomyxoma,AAM)是罕见的特殊类型软组织肿瘤。1994年WHO将其归类为软组织中的良性肿瘤,但具有侵袭性生长、术后易复发以及好发于女性的特点。     

精索侵袭性血管黏液瘤1例报告并文献复习

目的:分析1例精索侵袭性血管黏液瘤的临床表现、影像学和病理学特点以探讨其诊疗方式及预后。方法:回顾性分析我院2014年1月收治的1例精索侵袭性血管黏液瘤患者的临床资料,患者术前无特异性临床表现,术前诊断为阴囊肿物,遂行阴囊肿物切除术。结果:术后病理检查诊断为侵袭性血管黏液瘤,随访24个月肿瘤无复发和转移。结论:精索侵袭性血管黏液瘤较为罕见仅能依靠病理检查确诊;临床上容易与其他阴囊肿瘤混淆,手术切除是目前最为有效的治疗方式.因为该肿瘤的高复发性,需密切随访。     

泌尿生殖系侵袭性血管黏液瘤(附二例报告及文献复习)

目的　探讨泌尿生殖系侵袭性血管黏液瘤的临床特点及治疗。　方法　分析 2例泌尿生殖系侵袭性血管黏液瘤的临床资料。例 1,男 ,5 5岁 ,表现为腹股沟区无痛性肿物 ,B超示低回声肿物 ,行肿物完整切除术。例 2 ,女 ,14岁 ,主要症状有尿频、血尿、排尿困难和尿道口肿物 ,IVU、CT及三维血管成像等明确肿瘤范围及血供 ,行膀胱大部分切除及输尿管再植术。结合文献复习讨论。　结果　 2例患者随访 2～ 6个月 ,未见肿瘤复发和转移。例 1病理诊断为精索旁侵袭性血管黏液瘤 ,免疫组化 :Vimentin( )、Desmin( - )、SMA( )、S 10 0 ( - )。例 2病理诊断为膀胱侵袭性血管黏液瘤 ,免疫组化 :CD3 4 ( ) ,Desmin( - ) ,Vimentin( )Caldesmon ( - ) ,ER( - ) ,PR ( - ) ,SMA( ) ,S 10 0 ( - )。　结论　侵袭性血管黏液瘤是一种罕见的、有局部侵袭特性的良性肿瘤 ,确诊依赖病理学及免疫组织化学检查。治疗需行肿瘤完整切除 ,对于切除困难及复发性肿瘤可选择放疗及内分泌治疗。长期随访和影像学检查对确定肿瘤复发和手术治疗非常重要     

肾侵袭性血管黏液瘤1例报告

<正>侵袭性血管黏液瘤(aggressiveangiomyxoma,AAM)来源于间充质细胞,是一种罕见的、多发生于女性的良性肿瘤。其常发生部位为会阴部、外阴及盆腔区,且女性发病率是男性的6倍以上^[1-3]。其临床特点为生长缓慢、无特异性症状,肿瘤可向局部周围侵袭、易复发,但无转移风险,预后良好。原发于肾脏的AAM更为少见。本文报告2021年2月上海交通大学医学院附属仁济医院收治的1例肾侵袭性血管黏液瘤病例,结合相关文献复习,探讨肾血管黏液瘤的诊治方法。     

男性侵袭性血管粘液瘤的临床特点及诊疗方法

侵袭性血管粘液瘤(aggressive angiomyxoma,AAM)是一种罕见的良性肿瘤,男女发病率约为1∶6.6,好发于男性腹股沟区、阴囊、精索、前列腺、阴茎、臀部等部位。组织病理及免疫组化是诊断的金标准,手术治疗为主要治疗手段,内分泌及血管介入栓塞等治疗为辅助治疗手段。     

外阴侵袭性血管粘液瘤累及盆腔伴子宫肌瘤1例及文献复习

侵袭性血管粘液瘤(aggressive angiomyxoma,AAM)是一种罕见的软组织间叶性肿瘤,具有侵袭性强、易复发、少见转移、生长缓慢等特点,主要发生于生育年龄女性盆腔及会阴部。本文报道1例外阴AAM累及盆腔合并子宫肌瘤的患者,术前疑诊外阴AAM,开腹子宫肌瘤剔除便于同时在术中充分探查外阴肿物蒂部,并进行满意切除。通过文献复习,回顾此病的诊断过程、治疗方法及愈后情况。     

胸椎管内血管周细胞瘤致脊髓压迫症1例报道

<正>血管周细胞瘤(HPC)又称血管外皮细胞瘤,是一种罕见的源于软组织血管外皮细胞或未分化的间质细胞且具有侵袭性的中间型肿瘤。HPC可发生于身体任何部位,以深部软组织多见,神经系统的HPC较为少见,而源于椎管内的HPC更为罕见。我院于2014年11月收治了1例T4~T7范围椎管内HPC导致脊髓压迫症的患者,经手术治疗取得良好效果,报告如下。     

血管肉瘤3例临床病理分析并文献复习

正血管肉瘤是一类少见的恶性血管源性肿瘤,占软组织肉瘤的2%～4%[1]。肿瘤细胞在一定程度上具有正常血管内皮细胞的形态和功能特点[2]。约有50%的病例发生于皮肤,发生在实质脏器的较罕见。由于部位罕见,再加上形态学特殊、侵袭性强、预后差,诊断时有必要与低分化癌、Kaposi肉瘤、上皮样肉瘤等疾病进行鉴别。本院2016～2018年收集血管肉瘤3例,总结报道如下,并结合相关文献分析其     

Deep (aggressive) angiomyxoma of the vagina misdiagnosed as Gartner cyst: A case report

Introduction and importanceAggressive angiomyxoma is a rare soft tissue tumor. Aggressive angiomyxoma is a slow-growing vulvovaginal mesenchymal neoplasm with a marked tendency for local recurrence, but with a low tendency to metastasize. As it has a predilection for the pelvic and perineal regions, Aggressive angiomyxoma is often misdiagnosed.This case report documented rare case of misdiagnosed Aggressive Angiomyxoma as Gartner duct cyst.Presentation of caseThis article report a case of 31 year old women who complained mass came out from vagina without any urinary symptom and trauma. Physical examination and ultrasound finding suggested that the mass was Gartner Duct cyst. Management in this case was excision of the vaginal cyst. Histopathology examination revealed Deep (aggressive) angiomyxoma.DiscussionThe rarity of Deep (Aggressive) Angiomyxoma makes the preoperative diagnosis fairly difficult. Aggressive angiomyxoma is often misdiagnosed as it may have similar clinical presentation to common lesions such as Bartholin cyst or prolapse vaginal wall, Gartner cyst or levator hernia. Aggressive Angiomyxoma should be considered as differential diagnosis in patient with vaginal cyst.ConclusionAggressive Angiomyxoma is rare condition. Preoperative diagnosis and management are challenging. Long term follow op and evaluation should be done due to high rate of recurrence.     

Aggressive angiomyxoma in the scrotum expressing androgen and progesterone receptors

Aggressive angiomyxoma is a rare benign mesenchymal myxoid tumor that arises from the pelvic soft tissues and perineum in relatively young females. This tumor has the ability to infiltrate locally and has a high risk of local recurrence after extirpation, but no potential to metastasize. We report here a rare case of aggressive angiomyxoma that developed in the scrotum of a 47-year-old male. Immunostaining of the resected specimen revealed that the tumor cell nuclei stained strongly and diffusely for androgen receptors (80% of the tumor cells), and moderately and partly for progesterone receptors (20% of the tumor cells). However, staining was negative for estrogen receptors. It is highly suggested that the growth of aggressive angiomyxoma in males may depend on androgen manipulation, contrary to its frequent and close association with estrogen receptor expression, which has been reported in females.     

Recurrent aggressive angiomyxoma of the urinary bladder. Case report and review of the literature

Aggressive angiomyxoma is a rare neoplasm which predominantly involves the female pelvis and perineum. Forty-four cases have been reported in the world literature, including 10 cases in men. To the best of our knowledge, the first case of recurrent aggressive angiomyxoma of the urinary bladder is presented here. Operative management, radiologic features and pathological findings are discussed.     

Periurethral aggressive angiomyxoma: a case report

Aggressive angiomyxoma is a rare soft tissue tumor of the pelvis. Notorious for its locally infiltrative behavior, this tumor is identified by pathological appearance. Grossly gelatinous, spindle cells widely separated by collagen fibrils with vascular components can be microscopically visualized. Wide local excision is the treatment of choice. A 19-year-old woman presented with a periurethral mass that extended beyond the hymen with Valsalva. With imaging, the differential was narrowed to a soft tissue mass. Surgical excision was performed and histopathological findings were consistent with the diagnosis of aggressive angiomyxoma. Twenty-four months later the patient remains recurrence free. The typical findings of aggressive angiomyxoma are highlighted as well as the novel presentation as a periurethral mass. Histological and radiological findings are reviewed as well as current treatment options.     

Angiomyxoma diagnosed in a man presenting for abdominal lipectomy

Aggressive angiomyxoma is a rare tumour that is locally infiltrative but nonmetastasizing. It occurs nearly exclusively in adult women of childbearing age and almost always arises in the perineum and pelvic area. A case of angiomyxoma occurring in a middle-aged, morbidly obese man is reported. The clinical presentation was one of progressing scrotal edema and enlargement with subsequent development of scrotal abscesses, requiring several incisions and drainages as well as oral and intravenous antibiotics. His symptoms and body habitus left him in a significantly debilitated state, prompting him to seek treatment for his conditions. He initially presented for abdominal lipectomy. However, due to the chronic scrotal infections and enlargement, scrotectomy was recommended before any other surgical procedures. A scrotectomy was performed by the urology service. Pathological diagnosis of the excised tumour was an aggressive angiomyxoma. Given the rarity of this tumour, especially in males, the proper diagnosis and treatment of angiomyxoma is still being investigated. With this in mind, the physical signs and symptoms that characterize this condition are presented and treatment options are reviewed.     

A solitary encapsulated pelvic aggressive angiomyxoma

Aggressive angiomyxoma (AAM) was first reported in 1983 as a distinct, slow growing, benign but locally infiltrative, soft tissue tumour. It usually arises in the pelvic and perineal organs, mostly in women. A 47-year-old woman was found to have a large encapsulated retroperitoneal aggressive angiomyxoma. The mass was completely excised via abdomino-perineal approach, and no recurrence noted on MRI at 19 months' follow-up. The encapsulation of this tumour together with other reported rare presentations, suggest an isolated mesenchymal cell origin. A review of the literature is provided.     

Aggressive angiomyxoma of the pelvis surgical management in a case with delayed diagnosis

Introduction and importanceAggressive angiomyxoma is characterized as a non-capsulated soft mass with the ability to progress to surrounding tissues but without metastasis to distant tissues. Slowing tumor extension leading delayed tumor diagnosis, expression of different types of hormonal receptors, therapeutic ineffectiveness of noninvasive treatment approaches and misdiagnosis have remained as the major challenges for managing this tumor.Case presentationHerein, we described a case of aggressive angiomyxoma located in the posterior of the uterus and vagina that as successfully managed surgically to remove tumor mass followed by gonadotropin-releasing hormone (GnRH) agonist to prevent tumor recurrence.Clinical discussionSurgical resection is the treatment of choice in aggressive angiomyxoma with complete success rate, however despite such successfulness, about two-thirds of patients experienced postoperative recurrence rate that could be prevented by hormone-based therapy especially GnRH agonist.ConclusionAggressive angiomyxoma is a rare tumor with locally invasive behavior. As misdiagnosis is common imaging like MRI with DWI should be considered. The best treatment is surgical resection by experienced surgeons in tertiary referral hospitals. Even with complete resection, the recurrence rate is high. So adjuvant medical treatment seems to be necessary.     

Carney Complex: case report and review

Carney complex is a very rare multiple neoplasia syndrome with cardiac, cutaneous, and neural tumours with a variety of pigmented lesion of skin. We are reporting a rare case of carney complex in which left atrial myxoma with superficial angiomyxoma, giant cell tumour of bone and lentigines showed a unique association. This patient underwent successful surgical excision of left atrial myxoma under cardiopulmonary bypass.