Characteristics and Prediction of Lung Cancer Mortality in China from 1991 to 2013

Objective: To describe and analyze the epidemiological characteristics of lung cancer mortality in China from1991 to 2013, forecast the future five-year trend and provide scientific evidence for prevention and managementof lung cancer. Materials and Methods: Mortality data for lung cancer in China from 1991 to 2013 were usedto describe epidemiological characteristics. Trend surface analysis was applied to analyze the geographicaldistribution of lung cancer. Four models, curve estimation, time series modeling, gray modeling (GM) andjoinpoint regression, were performed to forecast the trend for the future. Results: Since 1991 the mortality rate oflung cancer increased yearly. The rate for males was higher than that for females and rates in urban areas werehigher than in rural areas. In addition, our results showed that the trend will continue to increase in the ensuing5 years. The mortality rate increased from age 45-50 and peaked in the group of 85 years old. Geographicalanalysis indicated that people living in northeast China provinces and the coastal provinces in eastern China hada higher mortality rate for lung cancer than those living in the centre or western Chinese provinces. Conclusions:The standardized mortality rate of lung cancer has constantly increased from 1991 to 2013, and been predictedto continue in the ensuing 5 years. Further efforts should be concentrated on education of the general public toincrease prevention and early detection. Much better prevention and management is needed in high mortalityareas (northeastern and eastern parts of China) and high risk populations (45-50-year-olds).     

Liver Cancer Mortality Characteristics and Trends in China from 1991 to 2012

Purpose: To investigate the distribution of liver cancer mortality as well as its developing trend froml991 to 2012, forecast the future five-year trend, and provide a basis for the comprehensive prevention andmanagement. Materials and Methods: Mortality data for liver cancer in China from 1991 to 2012 were usedto describe characteristics and distribution of liver cancer mortality. Trend surface analysis was used to studythe geographical distribution of liver cancer mortality. Curve estimation, time series modeling, gray modeling(GM) and joinpoint regression were used to predict and forecast future trends. Results: The mortality rate ofliver cancer has constantly increased in China since 1991. Rates in rural areas are higher than in urban areas,and in males are higher than in females. In addition, our data predicted that the trend will continue to increasein the next 5 years. The age-specific mortality of liver cancer increases with age and peaks in the group of 80-84years old. Geographical analysis showed the liver mortality rate was higher in the southeast provinces, such asJiangsu, Zhejiang and Guangdong, and southwest regions like Guangxi Province. Conclusions: The standardizedmortality rate of liver cancer in China has consistently increased from 1991 to 2012, and the upward trend ispredicted to continue in the future. Much better prevention and management of liver cancer is needed in highmortality areas (the southwestern and southeastern parts of China) and high mortality age groups (80- to84-year-olds), especially in rural areas.     

Cervical Cancer Mortality Trends in China, 1991-2013, and Predictions for the Future

Background: To analyze cervical cancer mortality trends in China from 1991-2013 and forecast the mortalitydistribution in future five years (2014-2018), and provide clues for prevention and treatment. Materials andMethods: Mortality data for cervical cancer in China from 1991 to 2013 were used to describe the epidemiologicalcharacteristics and distribution, including the trend of the standardized mortality rate, urban-rural differences,and age variation. Trend-surface analysis was used to analyze the geographical distribution of mortality. Curveestimation, time series, gray modeling, and joinpoint regression were performed to predict and forecast mortalitytrends. Results: In recent years, the mortality rate of cervical cancer has increased, and there is also a steadyincrease in the incidence from 2003 to 2013 in China. Mortality rates in rural areas are higher than in urbanareas. The mortality dramatically increases in the 40+ yr age group, reaching a peak in the >85 yr age group.In addition, geographical analysis showed that the cervical cancer mortality increased from the southwestto west-central and from the southeast to northeast of the country. Conclusions: The incidence rate and themortality rate are increasing from 1991 to 2013, and the predictions show this will continue in the future. Thus,implementation of prevention and management programs for cervical cancer are necessary in China, especiallyfor rural areas, young women in urban areas, and high risk regions (the west-central).     

Epidemiological Characteristics and Prediction of Esophageal Cancer Mortality in China from 1991 to 2012

Background: To analyze the mortality distribution of esophageal cancer in China from 1991 to 2012, to forecast the mortality in the future five years, and to provide evidence for prevention and treatment of esophageal cancer. Materials and Methods: Mortality data for esophageal cancer in China from 1991 to 2012 were used to describe its epidemiological characteristics, such as the change of the standardized mortality rate, urban-rural differences, sex and age differences. Trend-surface analysis was used to study the geographical distribution ofthe mortality. Curve estimation, time series, gray modeling, and joinpoint regression were used to predict the mortality for the next five years in the future. Results: In China, the incidence rate of esophageal cancer from 2007 and the mortality rate of esophageal cancer from 2008 increased yearly, with males at 8.72/105 being higher than females, and the countryside at 15.5/105 being higher than in the city. The mortality rate increased from age 45. Geographical analysis showed the mortality rate increased from southern to eastern China, and fromnortheast to central China. Conclusions: The incidence rate and the standardized mortality rate of esophageal cancer are rising. The regional disease control for esophageal cancer should be focused on eastern, central and northern regions China, and the key targets for prevention and treatment are rural men more than 45 years old. The mortality of esophageal cancer will rise in the next five years.     

Mortality Characteristics and Prediction of Female Breast Cancer in China from 1991 to 2011

Aims: To analyze time-dependent changes in female breast cancer (BC) mortality in China, forecast the trendin the ensuing 5 years, and provide recommendations for prevention and management. Materials and Methods:Mortality data of breast cancer in China from 1991 to 2011 was used to describe characteristics and distribution,such as the changes of the standardized mortality rate, urban-rural differences and age differences. Trendsurfaceanalysis was used to study the geographical distribution of mortality. In addition, curve estimation, timeseries modeling, Gray modeling (GM) and joinpoint regression were performed to estimate and predict futuretrends. Results: In China, the mortality rate of breast cancer has increased yearly since 1991. In addition, ourdata predicted that the trend will continue to increase in the ensuing 5 years. Rates in urban areas are higherthan those in rural areas. Over the past decade, all peak ages for death by breast cancer have been delayed,with the first death peak occurring at 55 to 65 years of age in urban and rural areas. Geographical analysisindicated that mortality rates increased from Southwest to Northeast and from West to East. Conclusions: Thestandardized mortality rate of breast cancer in China is rising and the upward trend is predicted to continuefor the next 5 years. Since this can cause an enormous health impact in China, much better prevention andmanagement of breast cancer is needed. Consequently, disease control centers in China should place more focuson the northeastern, eastern and southeastern parts of China for breast cancer prevention and management,and the key population should be among women between ages 55 to 65, especially those in urban communities.     

中国胃癌死亡率20年变化情况分析及其发展趋势预测

目的　分析中国胃癌死亡 2 0年的变化情况 ,探讨其变化规律、可能的发展趋势。方法对基本采用同一方法处理的中国 2 0世纪 70年代和 90年代两次死因调查结果进行对比。结果　 90年代胃癌调整死亡率男性增长 11.0 % ,女性增长 6.3 % ;胃癌死亡率 70年代城市略高于农村 ,90年代农村高于城市 3 7.0 % ;90年代城市胃癌调整死亡率男、女性分别下降 2 2 .2 %、2 6.7% ,而农村男、女性分别上升 2 6.4%和 2 2 .1%。无论城市还是农村 ,90年代胃癌死亡的男、女性之比均较 70年代略有上升 ,胃癌死亡危害男性高于女性、且农村高于城市。 90年代男、女性胃癌死亡率下降的省 (市 )各有 12个 ,分别占 44.0 % (12 / 2 7) ;除江苏省外 ,女性的下降百分比均高于男性 ;胃癌死亡率上升在前 6位的省 (市 ) ,男性增幅均高于女性。结论　中国胃癌死亡总的呈上升趋势 ,但在 2 7个省 (市 )中则有升有降 ;城乡之间 ,城市下降 ,农村上升 ;与世界各国比较 ,中国男、女性胃癌世界调整死亡率居于首位。 2 0年的胃癌死亡率在 3 0～ 59岁年龄组中呈下降趋势 ,60岁以上年龄组呈上升趋势 ,因而人口老化是胃癌死亡率上升的重要因素     

2004—2018年中国大陆地区城乡居民结直肠癌死亡趋势分析

目的 分析我国城乡2004—2018年结直肠癌死亡流行病学特征,为预防控制结直肠癌发病与死亡提供科学依据。方法 分析中国疾病预防控制中心发布的全国605个监测点的2004—2018年结直肠癌死亡病例,根据年龄、性别和地区进行分层,计算结直肠癌粗死亡率（crude mortality rate,CMR）、年龄标化死亡率（age-standardized mortality rate,ASMR）及其年度变化百分比（annual percent change,APC）。结果 2004—2018年我国结直肠癌死亡病例共213 513例,CMR为9.67/10万,ASMR为6.52/10万。15年间我国结直肠癌CMR呈上升趋势（APC=3.30%,P<0.001）。城市地区结直肠癌ASMR无明显变化,但东、西部农村地区结直肠癌ASMR呈上升趋势（APC=1.13%,P=0.020;APC=1.80%,P=0.004）,中部农村地区结直肠癌ASMR呈下降趋势（APC=-1.22%,P=0.010）。城乡地区男性结直肠癌CMR均高于女性（P<0.001）,城市地区女性结直肠癌ASMR呈下降趋势（APC=-1.10%,P<0.001）。城市地区20~39岁和40~59岁年龄组的结直肠癌ASMR呈下降趋势（APC=-3.04%,P=0.007;APC=-1.98%,P=0.002）;农村地区≥60岁年龄组结直肠癌ASMR呈上升趋势（APC=0.86%,P=0.030）。结论 我国结直肠癌死亡率逐年上升,城乡地区人群结直肠癌死亡率在年龄、性别、地区等各层均存在显著差异,未来应加大对农村地区人群结直肠癌的防控,以早期发现、诊断和治疗。     

云南省肿瘤登记地区2011—2015年宫颈癌发病和死亡特征及时间趋势

目的 了解云南省肿瘤登记地区2011—2015年宫颈癌的发病和死亡特征及时间趋势,为开展宫颈癌防治提供参考.方法 收集整理2011—2015年云南省肿瘤登记地区宫颈癌(ICD-10编码为C53)的发病死亡病例.分城乡统计宫颈癌的发病率、死亡率、标化发病率、标化死亡率、截缩率、累积率(0～74岁)、趋势变化年度百分比(A...     

Incidence and mortality of colorectal cancer in China, 2011

Objective: Colorectal cancer is the third most common type of cancer and the fourth leading cause of cancer-related death in the world. This article provides the most up-to-date overview of colorectal cancer burden in China.Methods: Totally 234 cancer registries submitted data of 2011 to the National Central Cancer Registry(NCCR). Qualified data from 177 registries was pooled and analyzed. The crude incidence and mortality rates of colorectal cancer were calculated by age, gender and geographic area. The numbers of new cases and deaths were estimated using the 5-year age-specific cancer incidence/mortality rates and the corresponding populations. China census in 2000 and Segi’s world population were applied for age standardized rates.Results: The estimate of new cases diagnosed with colorectal cancer of China in 2011 was 310,244(178,404 for males and 131,840 for females, 195,117 in urban areas and 115,128 in rural areas), accounting for 9.20% of overall new cancer cases. The crude incidence of colorectal cancer ranked fourth in all cancer sites with rate of 23.03/100,000(25.83/100,000 for males and 20.08/100,000 for female, 28.25/100,000 in urban areas and 17.54/100,000 in rural areas). The age-standardized rates by China population and by World population were 16.79/100,000 and 16.52/100,000, respectively. The estimated number of colorectal cancer deaths of China in 2011 was 149,722(86,427 for males and 63,295 for females, 91,682 in urban areas and 58,040 in rural areas), accounting for 7.09% of overall cancer deaths. The crude mortality rate for colorectal cancer ranked fifth leading cause of cancer-related death in all cancer sites with rate of 11.11/100,000(12.51/100,000 for males and 9.64/100,000 for female, 13.27/100,000 in urban areas and 8.84/100,000 in rural areas). The age-standardized rates by China population and by World population for mortality were 7.77/100,000 and 7.66/100,000, respectively. For both of incidence and mortality, the rates of colorectal cancer were much higher in males than in females, and in rural areas than in urban areas. The rate of colorectal cancer increased greatly with age, especially after 40 or 45 years old.Conclusions: Colorectal cancer is a relative common cancer in China, especially for males in urban areas. Targeted prevention and early detection programs should be carried out.     

云南省肿瘤登记地区2011—2016年肺癌发病和死亡特征及时间趋势

目的 了解云南省肿瘤登记地区2011—2016年肺癌的发病死亡特征和流行趋势,为开展肺癌防治提供建议。方法 收集整理2011—2016年云南省肿瘤登记地区肺癌的发病死亡病例。分城乡统计肺癌的发病率、死亡率、标化发病率、标化死亡率、截缩率、累积率(0~74岁)、年度变化百分比(Annual percentage change,APC)。结果 云南省肿瘤登记地区2011—2016年肺癌发病粗率为42.05/10万,中标率为28.38/10万,世标率为28.21/10万,累积率(0~74岁)为3.48%,截缩率为55.38/10万。男性发病率为58.52/10万,中标率40.53/10万,女性发病率为25.11/10万,中标率16.62/10万。城市地区发病率为44.14/10万,中标率28.11/10万,农村地区发病率为39.40/10万,中标率29.02/10万。云南省肿瘤登记地区2011—2016年肺癌死亡粗率为33.16/10万,中标率为28.33/10万,世标率为21.64/10万,累积率(0~74岁)为2.61%,截缩率为38.96/10万。男性死亡率为47.47/10万,中标率32.32/10万,女性死亡率为18.44/10万,中标率11.71/10万。城市地区死亡率为34.54/10万,中标率21.28/10万,农村地区死亡率为31.47/10万,中标率22.81/10万。年龄别发病率和死亡率均0~34岁组处于较低水平,35-岁组后增加迅速。2011—2016年肺癌合计、城市地区和农村地区发病死亡变化趋势差异均无统计学意义(P＞0.05),但农村地区女性肺癌粗发病率APC为10.6%,标化发病率APC为9.8%,农村地区女性粗发病率及标化发病率呈上升趋势(P＜0.05)。结论 云南省2011—2016年肿瘤登记地区肺癌发病/死亡总体低于全国和西部地区水平,农村女性发病率和死亡率的年度变化呈上升趋势。建议继续扩大肺癌早诊早治覆盖面,积极开展控烟活动。     

结直肠癌流行病学趋势

结直肠癌已严重威胁人类的健康, 2012年全世界约有136万结直肠癌新发病例,是世界第3高发恶性肿瘤,在世界男性发病排第3位,女性排第2位;死亡约69万例, 居恶性肿瘤第4位。2010年我国结直肠癌新发病例数已超过27万,死亡病例13万以上。世界结直肠癌发病死亡比例均随时间而增加,且整体趋势为男性高于女性,发达地区高于欠发达地区,城市高于农村。在发达国家,90％以上患者年龄在50岁以上,但在发展中国家,患者发病年龄较小。本文以最新数据就世界结直肠癌流行病学现状作一综述,以期为今后结直肠癌的防治策略提供病因依据和理论支持。     

1988-2002年中国10个市县大肠癌的流行特征

目的 了解中国人群中大肠癌的发病、死亡情况及流行特征.方法 从<中国试点市、县恶性肿瘤的发病与死亡>第1～3卷中,提取1988--2002年肿瘤登记资料完整的10个市县的大肠癌数据资料,统计分析1988--1992年、1993--1997年、1998--2002年3个时期大肠癌的发病率和死亡率,评价大肠癌1988--2002年15年问的流行趋势.结果 1988--2002年中国10个市县共登记大肠癌新发病例62 793例,占全部恶性肿瘤新发病例的9.27%,居第4位.粗发病率为20.10/10万,中国人口调整率(简称中调率)为11.75/10万,世界人口调整率(简称世调率)为15.63/10万.大肠癌死亡35 545例,占全部恶性肿瘤死亡病例的7.37%,居第5位.粗死亡率为11.38/10万,中调率为6.35/10万,世调率为8.70/10万.1988--2002年大肠癌发病率和死亡率均呈上升趋势,发病率增长38.56%,死亡率增长15.30%;呈现男性高于女性、城市高于农村的流行特征.结肠癌的发病率(10.77/10万)高于直肠癌(9.33/10万).1988--1992年和1993--1999年2个时期,直肠癌死亡率均高于结肠癌,而1998--2002年结肠癌死亡率高于直肠癌.结论 1988--2002年中国10个市县大肠癌发病率和死亡率均呈上升趋势,应进一步加强全人群大肠癌的预防和诊治工作.     

2014年广西肿瘤登记地区结直肠肛门癌发病和死亡分析

目的  分析2014年广西结直肠肛门癌发病和死亡情况。方法  按照全国肿瘤登记中心制定的审核方法和评价标准评估广西肿瘤登记地区上报的2014年肿瘤登记数据,将9个入选的肿瘤登记地区的肿瘤发病、死亡和人口数据进行汇总,按地区（城乡）、性别、年龄别分层,计算结直肠肛门癌的发病率、死亡率、构成比和截缩率等。人口标准化率根据2000年全国人口普查结构和Segis′s世界人口结构。结果  2014年广西纳入分析的9个肿瘤登记地区结直肠肛门癌新发病例为1 716例（其中男性1 039例,女性677例）,发病率为24.74/10万,中标率为19.68 /10万,世标率为19.37/10万,男性发病率高于女性（28.73% vs 20.40%,χ²=48.433,P<0.001）;城市地区发病率为36.19/10万,中标率为27.45/10万;农村地区发病率为19.24/10万,中标率为16.07/10万。结直肠肛门癌死亡病例827例（其中男性518例,女性309例）,死亡率为11.93/10万,中标率为9.06/10万,世标率为9.00 /10万,男性死亡率高于女性（14.32% vs 9.31%,χ²=36.400,P<0.001）;城市地区死亡率为17.63/10万,中标率为13.21/10万;农村地区死亡率为9.18/10万,中标率为7.13/10万。结论  广西肿瘤登记地区结直肠肛门癌发病和死亡例数男性均高于女性,城市地区高于农村地区,45岁以上的中老年人群尤其是城市地区男性人群是重点开展肿瘤防治工作的对象。     

2011—2016年云南省肿瘤登记地区女性乳腺癌发病和死亡情况分析

目的 掌握云南省2016年女性乳腺癌发病和死亡情况及2011—2016年变化趋势,为乳腺癌防控提供参考依据.方法 利用云南省2011—2016年的肿瘤登记数据和相关人口数,审核、评估数据,计算女性乳腺癌发病率、死亡率、标化率、0～74岁累积率、35～64岁截缩率等指标,采用Joinpoint 4.8计算年度变化百分比(...     

2013—2017年黑龙江省肿瘤登记地区肝癌发病与死亡分析及变化趋

目的 分析黑龙江省肿瘤登记地区肝癌发病死亡情况及时间变化趋势。方法 收集2013—2017 年黑龙江省肿瘤登记地区上报的肝癌发病与死亡资料,计算发病（死亡）率、标化发病（死亡）率、累积率（0~74岁）等,标化率采用2000 年全国人口普查标准人口构成和 Segi's 世界标准人口构成作为标准。年度变化百分比（APC）使用Joinpoint软件计算。结果 2013—2017年黑龙江省肿瘤登记地区肝癌发病率为29.13/10万,中标率为17.18/10万,累积率（0~74岁）为1.96%。 其中男性肝癌发病率（42.59/10万）高于女性（15.90/10万）,农村地区肝癌发病率（35.05/10万）高于城市地区（26.75/10万）。2013—2017年黑龙江省肿瘤登记地区肝癌死亡率为26.53/10万,中标率为15.90/10万,累积率（0~74岁）为1.78%。其中男性肝癌死亡率（38.33/10万）高于女性（14.93/10万）,农村地区肝癌死亡率（30.65/10万）高于城市地区（24.88/10万）。2013—2017年发病中标率呈下降趋势,死亡中标率无明显变化趋势（P>0.05）,男性发病中标率呈下降趋势（P<0.05）。结论 黑龙江省肝癌负担较重,发病率整体呈下降趋势,死亡趋势较平稳。防治工作中应重点关注男性及农村地区,采取综合措施进行有效预防与控制。     

2011—2015年合肥市消化系统恶性肿瘤发病趋势分析

目的 分析2011—2015年合肥市消化系统恶性肿瘤发病特征和变化趋势。方法 收集2011—2015年合肥市消化系统恶性肿瘤发病数据,计算粗发病率、中国人口标化发病率、世界人口标化发病率等,采用Joinpoint软件计算中标发病率的年度变化百分比（annual percent change,APC）了解消化系统恶性肿瘤发病率随时间变化趋势,同时计算粗发病率的每岁变化百分比（APC）和平均每岁变化百分比（average annual percent change,AAPC）,评价男性和女性、城市和农村地区的消化系统恶性肿瘤发病年龄变化趋势。 结果 2011—2015年合肥市消化系统恶性肿瘤发病例数为53 990例,粗发病率为162.29/10万,中标率为135.57/10万,世标率为135.93/10万,占全部恶性肿瘤新发病例总数的55.66%。5年间总体发病率逐渐升高,但变化趋势不明显（APC=2.36%,95%CI：-7.75%~13.58%,P=0.527）。发病前5位分别为胃癌、食管癌、结直肠癌、肝癌和胰腺癌,占全部恶性肿瘤新发病例总数的53.64%,其中结直肠癌中标发病率随时间持续上升（APC=9.82%,95%CI：0.86%~19.57%,P=0.039）,其余癌种发病率虽然有所上升,但是变化趋势不明显（均P>0.05）。5年间总体发病率随年龄增长逐渐升高,在30岁以后快速上升。不同性别、城乡年龄别发病率变化趋势一致,分别在≥25岁年龄段（APC=9.60%,95%CI：8.01%~11.20%,P<0.001）和≥20岁年龄段（APC=10.74%,95%CI：9.30%~12.21%,P<0.001）迅速上升,其中在≥40岁人群中,男性发病率均高于女性;全部消化系统恶性肿瘤、胃癌、食管癌在≥20岁人群中,农村地区发病率均高于城市地区;而在≥50岁人群中,城市地区结直肠癌及胰腺癌发病率高于农村地区。 结论 2011—2015年合肥市消化系统恶性肿瘤发病水平逐渐上升,但总体变化趋势较平稳,表现为男性高于女性,农村地区高于城市地区,且不同性别、城乡年龄别发病率变化趋势一致的流行特征,未来合肥市仍需加强对消化系统恶性肿瘤的防治工作。     

2016年辽宁省肿瘤登记地区恶性肿瘤流行情况分析

目的 分析2016年辽宁省肿瘤登记地区恶性肿瘤流行状况。方法 收集2016年辽宁省肿瘤登记地区(35个县区)上报的恶性肿瘤发病与死亡资料,计算发病与死亡粗率、标化率、累积率(0~74岁)和年龄别率等,标化率使用Segi's世界标准人口年龄构成和2000年中国人口年龄构成为标准进行计算。结果 2016年辽宁省肿瘤登记地区恶性肿瘤发病率为383.54/10万,世标率为200.06/10万,中标率为204.44/10万,城市地区发病中标率(201.40/10万)高于农村地区(186.43/10万);40-岁及以上各年龄组发病率快速升高,在80-岁组达到峰值;35-岁以上各年龄组城市男性和女性恶性肿瘤发病率分别高于农村男性和女性;肺癌、结直肠癌、乳腺癌是辽宁省发病最高的恶性肿瘤。2016年恶性肿瘤死亡率为249.79/10万,世标率为123.00/10万,中标率为124.32/10万,城市地区死亡中标率(121.93/10万)低于农村地区(131.03/10万)。恶性肿瘤年龄别死亡率峰值在80-岁组。20~79岁男性各年龄组死亡率均为农村高于城市,55~79岁女性各年龄组死亡率均为农村高于城市。肺癌、肝癌、结直肠癌是辽宁省死亡率最高的肿瘤。结论 辽宁省恶性肿瘤发病和死亡均高于全国水平,总发病率和死亡率均为男性高于女性,城市发病率高于农村,农村死亡率高于城市,城乡居民恶性肿瘤负担差异明显。     

Ovary cancer incidence and mortality in China, 2011

Objective

To evaluate and analyze ovary cancer incidence and mortality in China in 2011 using ovary cancer data from population-based cancer registration in China, and to provide scientific information for its control and prevention.

Methods

Invasive cases of ovary cancer were extracted and analyzed from the overall Chinese cancer database in 2011, which were based on data from 177 population-based cancer registries distributing in 28 provinces. The crude, standardized, and truncated incidences and mortalities et al. were calculated and new and deaths cases from ovary cancer throughout China and in different regions in 2011 were estimated using Chinese practical population.

Results

The estimates of new ovary cancer cases and deaths were 45,223 and 18,430, respectively, in China in 2011. The crude incidence rate, age-standardized rate by Chinese standard population (ASR-C) and age-standardized rate by world standard population (ASR-W) incidence were 6.89/100,000, 5.35/100,000 and 5.08/100,000, respectively; the crude, ASR-C and ASR-W mortalities were 2.81/100,000, 2.01/100,000 and 1.99/100,000, respectively. The incidence and mortality in urban areas were higher than those in rural areas. The age-specific incidence and mortality increased rapidly from age 35-39 and peaked at age 60-64 or 75-79 years. After age 45 or 55, the age-specific incidence and death rates in urban were much higher than those in rural areas.

Conclusions

Compared with GLOBOCAN 2012 data, the ovary cancer incidence in China in 2011 was at middle level, but its mortality was at low level worldwide.     

2013—2017年黑龙江省肿瘤登记地区前列腺癌发病死亡情况及趋势分析

目的：分析2013—2017年黑龙江省肿瘤登记地区前列腺癌发病死亡情况及变化趋势。方法：收集2013—2017年黑龙江省肿瘤登记地区上报的前列腺癌发病与死亡资料,计算发病（死亡）率、标化发病（死亡）率、累积率（0~74岁）等,标化率采用2000年全国人口普查标准人口构成和Segi's世界标准人口构成作为标准。年度变化百分比（APC）使用Joinpoint软件计算。结果：2013—2017年黑龙江省肿瘤登记地区前列腺癌发病率为6.50/10万,中标发病率为3.71/10万,累积率（0~74岁）为0.35%。城市地区前列腺癌发病率（8.05/10万）高于农村地区（2.83/10万）。2013—2017年黑龙江省肿瘤登记地区前列腺癌死亡率为3.41/10万,中标死亡率为1.90/10万,累积率（0~74岁）为0.16%。城市地区前列腺癌死亡率（4.20/10万）高于农村地区（1.53/10万）。前列腺癌发病率和死亡率均随年龄升高呈上升趋势。2013—2017年黑龙江省肿瘤登记地区前列腺癌中标发病率和中标死亡率均呈上升趋势,但差异无统计学意义（P < 0.05）。结论：黑龙江省肿瘤登记地区前列腺癌发病率和死亡率均随年龄的增长而上升,城市地区高于农村地区,建议加强重点人群尤其是高龄人群的前列腺癌防治。     

2010—2016年广西肿瘤登记地区肝癌发病和死亡分析及变化趋势

目的 分析2010—2016年广西肿瘤登记地区肝癌发病和死亡特征及其变化趋势,为广西制定肝癌防控措施提供依据。方法 收集2010—2016年广西肿瘤登记地区上报的恶性肿瘤发病与死亡资料,计算肝癌发病率、死亡率、构成比、0~74岁累积率、35~64岁截缩率,按地区（城市/农村）、性别和年龄分层。采用2000年中国人口普查和Segi's世界人口计算年龄标准化率。采用Joinpoint模型对肝癌发病率和死亡率进行趋势分析。结果 2010—2016年广西肿瘤登记地区肝癌发病率为41.79/10万,中标率为34.86/10万,世标率为33.45/10万,0~74岁累积率为3.79%,35~64岁截缩率为68.60/10万;死亡率为34.56/10万,中标率为28.63/10万,世标率为27.63/10万,0~74岁累积率为3.12%,35~64岁截缩率为54.48/10万;男性发病率和死亡率均高于女性,农村地区高于城市地区。2010—2016年广西肿瘤登记地区肝癌发病和死亡水平呈明显上升趋势,发病率的APC为5.38%（95%CI：2.56%~8.29%,P<0.05）,死亡率的APC为9.23%（95%CI：3.83%~14.92%,P<0.05）。结论 2010—2016年广西肿瘤登记地区肝癌发病率和死亡率呈上升趋势,应针对肝癌致病因素和流行特征采取有效措施予以防控,35岁及以上男性（尤其农村）是开展早期筛查和干预的重点人群。