女性尖锐湿疣患者焦虑、抑郁症状的现状及影响因素分析

目的分析女性尖锐湿疣(CA)患者焦虑、抑郁症状的现状及影响因素,为制定更完善的护理措施提供理论依据。方法以方便抽样的方法,采用焦虑自评量表(SAS)、抑郁自评量表(SDS)对2011年1-9月在绍兴市7家医院门诊治疗的女性CA患者进行问卷调查。共调查200例,年龄18～65岁;已婚99例,离异或丧偶10例,未婚91例;性传播142例,间接传播58例;病程7d～6个月。结果女性CA患者的SAS总分为34.75±8.37,SDS为39.19±8.89,均高于国内常模SAS(29.78±10.07)和SDS(33.46±8.55)。本组患者焦虑发生率为23.5%,主要表现在焦虑、害怕、睡眠障碍等方面。患者的抑郁发生率为47.5%,主要表现在忧郁、性兴趣减退等方面。文化程度、职业和婚姻状况等因素对患者的焦虑、抑郁有显著影响(P<0.05)。结论女性CA患者的焦虑和抑郁发生率较高,症状较为严重。医护人员应为患者提供适当的心理支持,改善患者的焦虑和抑郁症状,提高患者的生活质量,早日恢复身心健康。     

围绝经期女性患者住院期问焦虑抑郁症状检出率和影响因素调查研究

目的：探究并分析围绝经期女性患者焦虑抑郁症状的检出率,调查影响围绝经期女性焦虑抑郁症状的因素。方法：回顾性分析我院收治的围绝经期女性患者250例,将其作为临床研究对象。采用抑郁自评量表、焦虑自评量表进行调查问卷,对患者的焦虑抑郁症状进行分析,调查患者抑郁焦虑症的影响因素。结果：250例围绝经期女性患者中抑郁症的检出率为22．80％,焦虑症的检出率为26．80％。不同年龄段的抑郁症、焦虑症的检出率不一样,其中50岁以上的患者抑郁症、焦虑症的检出率高。结论：围绝经期女性患者易发生抑郁焦虑症,导致患者抑郁焦虑症发生的主要因素有年龄、月收入、有无躯体疾病及夫妻关系。除了身体因素外,还有社会、心理、个性等方面的因素。     

认知疗法对梅毒血清固定女性患者焦虑抑郁情绪的影响

目的:探讨认知疗法对梅毒血清固定女性患者焦虑抑郁情绪的影响。方法:将120例梅毒血清固定女性患者随机分成干预组和对照组(各60例),两组治疗前均予以焦虑自评量表(SAS)和抑郁自评量表(SDS)评定其焦虑抑郁情绪,对照组常规青霉素驱梅治疗3周,干预组在常规治疗基础上加认知疗法,3周后对患者重新评分,并进行比较。结果:干预组患者治疗前后SAS、SDS评分比较,差异均有统计学意义(t值分别为12.79、13.86,P值均<0.01);对照组患者治疗前后评分比较,差异无统计学意义(t值分别为0.80、0.65,P值均>0.01)。结论:认知疗法对改善女性梅毒血清固定患者焦虑抑郁情绪有积极意义。     

尖锐湿疣患者焦虑、抑郁状况调查结果分析

目的:探讨尖锐湿疣(CA)患者的焦虑、抑郁状况,为制定CA综合治疗方案提供循证医学依据。方法:选择性病门诊的CA患者为研究对象。采用自行设计的调查问卷、自评焦虑量表(SAS)和自评抑郁量表(SDS)对患者焦虑和抑郁状况进行调查,并与中国常模对比,分析CA患者的心理状态与普通人群的差异,并分析相关影响因素。结果:共调查89例CA患者,SAS评分为(36.28±7.16)分,SDS评分为(39.00±9.74)分,总粗分均值均高于中国常模(U值分别为7.98、5.23,P值均<0.01)。出现焦虑24例(26.97%),抑郁36例(40.45%),程度多为轻度,同时有焦虑和抑郁者20例(占22.47%)。CA患者出现焦虑的影响因素主要为性取向非异性恋,而低收入、使用成瘾性药物则为发生抑郁的主要影响因素。结论:CA患者中焦虑与抑郁发生率较高,宜在临床诊疗中采取心理干预措施。     

尖锐湿疣患者的个性及心理健康状态调查

目的评定尖锐湿疣患者的个性特点及心理健康状态。方法用症状自评量表(SCL-90)、艾森克人格问卷(EPQ),分别对尖锐湿疣患者及健康对照人群各202例进行进行问卷调查。结果尖锐湿疣患者EPQ的E量表得分明显高于对照组,P量表得分与健康对照组无明显差异,N量表得分明显高于对照组,L量表得分低于对照组。说明尖锐湿疣患者个性外倾、情绪不稳。尖锐湿疣患者症状自评量表(SCL-90)中的躯体不适、强迫、抑郁、焦虑、恐怖得分高于对照组,其中强迫、抑郁、焦虑、恐怖得分明显高于对照组,人际关系、敌对、偏执、精神病性得分与对照组无明显差异。结论尖锐湿疣患者具有特殊的人格特征,存在明显的心理问题。主要表现在强迫症状、抑郁、焦虑、恐怖等症状。     

个案管理模式在处置HIV职业暴露中的作用研究及效果观察

目的探析处置人类免疫缺陷病毒(HIV)职业暴露中应用个案管理模式的作用与效果。方法选取2018年1月至2020年12月期间40例HIV职业暴露医护人员作为研究对象,所选对象在HIV职业暴露处置中均实施个案管理模式。记录与对比干预前后心理症状情况、焦虑与抑郁情绪变化情况。结果 40名医护人员干预后,症状自评量表(SCL-90)评分较干预前低,焦虑自评量表(SAS)评分与抑郁自评量表(SDS)评分较干预前低,差异有统计学意义(P 0.05)。结论在处置HIV职业暴露中实施个案管理模式,可减轻其心理症状,有效减轻焦虑与抑郁情绪。     

女性玫瑰痤疮患者生活质量调查分析

目的:调查玫瑰痤疮对女性患者生活质量的影响。方法:应用皮肤病生活质量指数(DLQI)调查表和Beck抑郁自评量表(BDI)对123例女性玫瑰痤疮患者进行问卷调查,并收集患者人口统计学基本信息,评估疾病亚型与严重程度。结果:DLQI评分为10.46±6.444;BDI评分提示存在严重抑郁症状的占5.69;单因素方差分析结果提示婚姻情况是重要影响因素;相关性分析结果显示DLQI评分、BDI评分、疾病严重程度三者之间呈正相关。结论:玫瑰痤疮对女性患者的生活质量有明显影响。患者易产生抑郁情绪,且这种影响与疾病的严重程度呈正相关,对已婚女性的影响大于未婚女性。因此对于玫瑰痤疮患者的治疗不仅限于药物治疗,同时要及早进行心理疏导。     

斑秃与精神心理因素关系的探讨

目的:对斑秃患者心理进行调查并作结果分析.方法:采用心理健康症状自评量表(SCL-90),对86例斑秃患者进行问卷调查分析.结果:SCL-90 测评结果显示:斑秃患者在人际关系、焦虑、抑郁和敌对性项的得分明显高于对照组,差异有统计学意义(P<0 05),女性斑秃患者在焦虑项的得分明显高于男性斑秃患者,差异有统计学意义(...     

女性阴道宫颈尖锐湿疣的综合护理临床分析

目的 分析、研究女性阴道-宫颈尖锐湿疣的临床护理。方法 选取某医院2017年2月至2019年2月采用ALAPDT联合电离子治疗阴道-宫颈尖锐湿疣的患者72例,采用随机数字表法分为对照组和观察组,各36例,对照组予以常规护理,观察组予以综合护理,探究阴道-宫颈尖锐湿疣患者的护理效果。结果 对照组疣体清除率、复发率为83.3%和22.2%,观察组疣体清除率、复发率为100.0%和5.6%,对比存在统计学差异(P 0.05);观察组焦虑自评量表(SAS)评分、抑郁自评量表(SDS)评分较对照组明显下降,对比存在统计学差异(P 0.05)。结论 女性阴道-宫颈尖锐湿疣的治疗配合综合护理干预可有效改善患者的临床疗效及心理状况。     

他汀类药物与患者抑郁、焦虑情绪的关系研究

目的探讨他汀类药物对患者抑郁、焦虑情绪产生的影响。方法应用抑郁自评量表（SDS）和焦虑自评量表（SAS）对患者抑郁、焦虑情绪状态进行评分,采用t检验初步比较应用他汀类药物治疗组和未服药组之间量表评分的差异;然后对2组的有关因素采用t检验或χ^2检验进行比较;最后,采用多元线性回归进行影响因素的分析。结果服药组与未服药组比较,抑郁和焦虑量表评分均无差异。结论他汀类药物对患者抑郁和焦虑情绪无影响。     

中外白癜风诊疗指南及共识比较

本文从白癜风分型、分期、病情评估、药物治疗及非药物治疗等方面比较了欧洲、美国、日本、韩国、中国等地区和国家的白癜风诊疗指南或共识, 概要分析各指南及共识中推荐的白癜风疗法和强调理念的异同, 以帮助临床医生为白癜风患者提供合适的个体化治疗方案。     

两种氯雷他定药物治疗湿疹、皮炎的成本效果分析

目的：对两种氯雷他定(百为坦和开瑞坦)治疗湿疹、皮炎的成本效果进行分析．方法：将患者分为两组，每组30例，分别服用百为坦和开瑞坦，除观察疗效外还进行成本效果分析。结果：两组疗效相当，均无明显的不良反应。但百为坦的治疗成本明显低于开瑞坦．结论：氯雷他定治疗湿疹、皮炎疗效高，安全性好。百为坦比开瑞坦治疗成本低。     

Treatment and prevention of rickettsial and ehrlichial infections

Rickettsial and ehrlichial infections are both carried by arthropod vectors. Both Rickettsia and Ehrlichia are small intracellular gram-negative coccobacilli. Clinical manifestations of Rickettsia range from spotted fevers to various forms of typhus. Human ehrlichiosis can present as monocytic ehrlichiosis or granulocytic anaplasmosis. Prevention is by avoidance of the responsible vectors. Therapy is usually with doxycycline, but chloramphenicol can also be used.     

Sterilization and care of surgical instruments and supplies

Adequate instrument handling and sterilization are important aspects of office surgery. Heat sterilization is the most reliable choice. The steam autoclave is highly recommended. Dry heat is effective but can pose some storage problems. Gas sterilization is useful for heat-sensitive materials but not practical for the private office. Cold "sterilization" is not reliable for incisional surgery. In addition to proper sterilization modality selection, the surgeon must observe important standards of instrument care, packing, and storage.     

Visual attention to and perception of undamaged and damaged versions of natural and colored female hair

Female hair color is thought to influence physical attractiveness, and although there is some evidence for this assertion, research has yet not addressed the question if and how physical damaging affects the perception of female hair color. Here we investigate whether people are sensitive (in terms of visual attention and age, health and attractiveness perception) to subtle differences in hair images of natural and colored hair before and after physical damaging. We tracked the eye‐gaze of 50 men and 50 women aged 31–50 years whilst they viewed randomized pairs of images of 20 natural and 20 colored hair tresses, each pair displaying the same tress before and after controlled cuticle damage. The hair images were then rated for perceived health, attractiveness, and age. Undamaged versions of natural and colored hair were perceived as significantly younger, healthier, and more attractive than corresponding damaged versions. Visual attention to images of undamaged colored hair was significantly higher compared with their damaged counterparts, while in natural hair, the opposite pattern was found. We argue that the divergence in visual attention to undamaged colored female hair and damaged natural female hair and associated ratings is due to differences in social perception and discuss the source of apparent visual difference between undamaged and damaged hair.     

角质形成细胞和成纤维细胞对白癜风发病和治疗的影响

黑素细胞在白癜风发病及治疗中是最关键的一环，但表皮、真皮间的沟通联系对皮损及非皮损皮肤的功能均具有重要影响，其中角质形成细胞、成纤维细胞及细胞外基质等非黑素细胞起了重要作用，并影响白癜风的发病。本文从细胞因子、氧化应激等角度总结了角质形成细胞、成纤维细胞对白癜风发病的影响及在临床治疗中的作用机制。     

Effects and interactions of increased environmental temperature and UV radiation on photoageing and photocarcinogenesis of the skin

Solar radiation is one of fundamental elements sustaining and maintaining life on earth. Previous studies on health effects from the sun exposure mostly focused on ultraviolet (UV) radiation. Although exposure to the solar radiation likely occurs in an environment with elevated temperature, the effects and interactions of elevated environmental temperature with UV radiation on the skin, especially in the context of ageing and carcinogenesis, have not been carefully examined. It is known that UVA radiation results in reduced production and increased degradation of dermal collagen, contributing to photoageing of the skin. Previous studies showed conflicting results regarding the effects of increased environmental temperature on dermal collagen. Additionally, we demonstrated that solar‐simulated radiation and increased environmental temperature have similar impacts on dermal fibroblasts through activation of distinct pathways. UVB radiation is well known for its carcinogenic capacity. Previously, it was reported that exposure to heat treatment before UVB radiation reduces epidermal keratinocyte cell death. We demonstrated that exposure to elevated environmental temperature prior to UVB radiation reduces UVB‐induced skin tumor formation. We proposed that alterations in molecular dynamics and quantum mechanics were involved for the observed increased environmental temperature‐induced protective effect against UVB damage. This review emphasizes that both environmental temperature and solar radiation are important elements in nature that have significant impacts on the human health, and future studies should focus on the biological effects and interactions of environmental temperature and solar radiation since this scenario is most relevant to the real‐world setting.