改良根向复位瓣术对种植二期手术患者实施附着龈重建治疗的临床修复效果观察

目的 探讨改良根向复位瓣术对种植二期手术患者实施附着龈重建治疗的临床修复效果.方法 回顾性分析本院2013年12月~2014年12月收治的13例行种植二期手术和同期附着龈重建治疗患者的临床资料,均利用改良根向复位瓣术进行附着龈重建.结果 入组的13例患者一共有15颗种植体接受治疗,术后14 d进行复查并制取印模的时候,经复查发现,15个种植位点中有13个黏膜均呈现愈合良好现象,其余2个黏膜发生炎症.术后1个月复查,在进行牙冠佩戴的时候,正常角化黏膜均良好形成.在有效角化黏膜宽度方面,治疗前,13例患者的平均为有效角化黏膜宽度为(0.19±0.44)mm,治疗后1个月复查,较之治疗前,宽度得到显著的增加,达到(2.61±0.46)mm,差异有统计学意义(P<0.05);治疗后6个月进行复查,较之治疗后1个月,宽度得到显著增加,达到(2.64±0.54)mm,差异有统计学意义(P<0.05),冠修复6个月后进行复诊,可以发现患者均处于良好的口腔卫生状况.患者的种植体均处于良好的稳定状态.重建角化黏膜与烤瓷冠紧密贴合,且未出现明显炎症.经牙周复查,各项指标均处于良好水平,其中改良菌斑指数为(0.71±0.81),出血指数为(0.74±0.63),探诊深度为(1.81±0.35)mm.结论 改良根向复位瓣术应用于种植二期手术患者附着龈重建治疗之后可以获得良好的临床修复效果.     

根向复位瓣在牙冠延长术中的临床应用

目的：评价根向复位瓣在牙冠延长术后的近期临床疗效。方法：对15例19颗需行牙冠延长术而附着龈宽度不足的患者行根向复位瓣术，观察术后1～6周临床效果。观察指标：①牙龈的色、形、质及断缘暴露是否良好；②茵斑指数（PLI）、出血指数（BI）和松动度（MD）；③牙龈缘的位置与相邻牙龈缘的位置关系（唇颊侧）及牙龈乳头的术后恢复情况；④附着龈宽度的变化。结果：患牙主观感觉良好，牙龈无炎症，牙龈缘高度与邻牙基本协调，术后断缘均暴露于龈上，有利于冠修复。结论：根向复位瓣术的实施，有利于断缘位于龈下方而生物学宽度及附着龈宽度不足的牙齿保存和修复。     

种植手术同期根向复位瓣附着龈重建的临床研究

目的探索一种简单高效的手术方法,用于增加种植体周围的附着龈宽度并且能缩短种植修复的疗程。探讨根向复位瓣附着龈重建术的效果。方法收集有种植修复需求的患者8例,但种植位点处附着龈宽度小于2 mm,行种植手术同期利用根向复位瓣技术进行附着龈重建。术后2周拆线。8周后常规种植上部修复并负荷。分别观察手术前、术后8周、修复完成即刻、修复完成1年时附着龈宽度的变化情况。结果所有患者种植体周围的附着龈宽度明显增加,修复完成1年后未见明显附着龈退缩。术后2周拆线,除1个种植位点在术后第2天因缝合线脱落致黏膜仍有炎症外,其余位点黏膜愈合良好。结论根向复位瓣附着龈重建术创伤小,并且同期种植手术可以缩短种植修复疗程,术后患者恢复效果较好。可以作为增加种植体周围附着龈宽度的简单高效的方法。     

牙龈切除术联合根向复位瓣术治疗慢性牙周炎合并Ⅲ度根分叉病变疗效观察

目的探讨牙龈切除术联合根向复位瓣术治疗慢性牙周炎合并Ⅲ度根分叉病变患者的临床效果。方法选取我院66例慢性牙周炎合并Ⅲ度根分叉病变患者,依据手术方式不同分组,各33例。对照组施行龈下刮治术+根面平整术治疗,观察组施行牙龈切除术+根向复位瓣术治疗。术后3个月,观察统计两组手术效果、术后并发症发生情况,并对比两组手术前后牙周相关指标[垂直探诊深度(VPD)、角化龈宽度(WKG)、菌斑指数(Plaque index,PLI)、临床附着水平(CAL)、牙龈出血指数(SBI)]及生活质量变化情况。结果观察组手术总有效率90.91%远高于对照组的66.67%,术后并发症发生率6.06%远低于对照组的27.27%,差异有统计学意义(P0.05);相较于对照组,术后观察组VPD、PLI及SBI水平均较低,生活质量评分均较高,差异有统计学意义(P0.05)。结论联合采用牙龈切除术、根向复位瓣术治疗慢性牙周炎合并Ⅲ度根分叉病变,可进一步提高治疗效果,显著降低垂直探诊深度、菌斑指数及牙龈出血指数,有效改善患者生活质量,且安全性较高。     

一种改良根向复位瓣术增宽附着龈的临床研究

目的探讨改良的根向复位瓣术增宽附着龈的临床效果。方法将已行种植一期手术,植体潜入式愈合,二期手术术前种植位点附着龈宽度不足2 mm的患者20例,随机分为研究组和对照组,各10例,研究组二期手术同期行改良根向复位瓣术,对照组行常规二期手术。比较二期术前,术后1个月及6个月术区附着龈宽度,附着龈重建情况及改良菌斑指数。结果术后1个月研究组附着龈宽度较术前平均增宽4.81 mm,且高于对照组[（5.72±0.86）mm比（1.23±0.55）mm,P<0.05],术后6个月亦高于对照组[（5.65±0.85）mm比（1.16±0.53）mm,P<0.05]。2周拆线时除研究组1个位点缝线脱落造成黏膜愈合不良外,2组黏膜均愈合较好,附着点重建情况比较差异有统计学意义（P<0.05）。2组术后6个月改良菌斑指数比较差异有统计学意义（P<0.05）。结论在种植二期手术同时进行改良根向复位瓣术,能有效增宽附着龈,缩短种植修复疗程,无须开辟第二术区,创伤较小,能够改善口腔卫生,为临床种植体周围附着龈宽度不足的治疗提供新的思路。     

附着龈重建在口腔种植修复中的应用

目的:对附着龈重建在口腔种植修复中的应用效果进行有效探究。方法:选取2014年1月-2015年4月本院口腔科接受种植修复术治疗的76例患者,采用随机数字表法分为观察组和对照组,每组38例。观察组患者采用附着龈重建治疗,对照组患者采用常规牙龈缝合,对比两组患者治疗效果。结果:观察组总有效率为97.4%,高于对照组的68.4%,治疗后观察组有效角化黏膜宽度高于对照组,牙周较对照组更为健康,差异均有统计学意义(P0.05)。结论:附着龈重建在口腔种植修复中应用效果显著,操作简单方便,应用价值高。     

附着龈重建在单颗上前牙缺失种植义齿修复中的应用

目的探讨附着龈重建在单颗上前牙缺失种植义齿修复中的应用效果。方法 2015年2月至2017年2月在我院完成种植义齿修复的单颗上前牙缺失患者中,伴有附着龈不足、轻度骨缺损、需行二期手术、采用的种植系统为Cortex的,共54例。将二期手术时拒绝接受附着龈重建的22例患者设为对照组,同意接受附着龈重建的32例患者中随机选取22例设定为实验组,术后一个月修复上部结构,修复完成半年后复诊,对比两组患者的有效角化黏膜宽度及牙周临床指标。结果实验组的有效角化黏膜宽度、探诊深度、改良菌斑指数、出血指数分别为(2.58±0.42)mm、(1.51±0.25)mm、(0.62±0.13)、(0.61±0.16),显著优于对照组的(2.19±0.37)mm、(1.77±0.30)mm、(0.69±0.08)、(0.83±0.18),差异具有统计学意义(P0.05)。结论在伴有附着龈不足的单颗上前牙种植修复中采用附着龈重建,可显著改善上部结构修复完成半年后的有效角化黏膜宽度、探诊深度、改良菌斑指数、出血指数,有利于缺牙区唇侧丰满度的恢复和种植体周组织健康的保持。     

附着龈重建在口腔种植修复中的应用方法及疗效观察

目的分析附着龈重建在口腔种植修复中的应用方法及效果;方法本研究所选20例(20个种植点)伴附着龈不足的种植牙二期手术患者均为我院2015年2月至2016年3月所收治,全部患者均给予种植牙二期手术治疗,并给予附着龈重建;结果术后4周的角化黏膜宽度显著优于术前(P0.05);术后半年,患者的角化黏膜宽度保持稳定,并没有发生显著炎症,紧密贴合烤瓷冠。探诊出血点的比率为20.0%(4/20),探诊深度、出血指数以及改良菌斑指数分别为(1.82±0.29)mm、(0.71±0.18)、(0.70±0.20)。结论在口腔种植修复中,应用附着龈重建具有比较理想的效果,同时开展附着龈重建和种植牙二期手术,操作简单方便,短期临床效果比较理想,具有推广价值。     

附着龈重建在口腔种植修复中的应用研究

目的:探析附着龈重建在口腔种植修复中的应用效果。方法:选取50例需要口腔种植修复的患者,按照个人意愿分为对照组和观察组,每组25例,对照组采用常规口腔修复治疗,观察组采用附着龈重建治疗。观察两组患者治疗效果、手术后5周有效角化黏膜宽度、总满意度、住院所需天数。结果:观察组临床治疗总有效率(96.00%)明显高于对照组(68.00%)(P<0.05);手术后5周有效角化黏膜宽度明显大于对照组(P<0.05);总满意度率(88.00%)明显高于对照组(60.00%)(P<0.05);住院所需天数明显少于对照组(P<0.05)。结论:与常规口腔修复方法相比,附着龈重建在口腔种植修复中不仅有利于提高临床治疗效果,改善有效角化黏膜宽度,更利于减少患者住院天数,提高满意度,附着龈重建具有独特的临床优势。     

附着龈重建在口腔种植修复中的运用研究

目的研究分析附着龈重建在口腔种植修复中的实际运用。方法选取本院于2013年1月至2018年1月收治的200例接受附着龈重建术的患者作为研究对象,采取双盲分组法进行分组,观察组(n=100)采取附着龈重建术进行治疗,对照组(n=100)采取传统治疗方式。比较2组患者的附着龈宽度、重建情况。结果术后3个月、6个月,观察组附着龈宽度显著宽于对照组(P0.05);观察组患者的重建协调情况均显著优于对照组(P0.05)。结论在口腔种植修复的过程中对附着龈患者采用附着龈重建术,可有效修复牙龈,提高重建协调率,降低重建缺陷率,修复效果显著,美观度高,是一种操作简便、应用价值高的治疗方法。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

CLINICAL SIGNIFICANCE OF SERUM CYTOKINES IL-1β,sIL-2R,IL-6,TNF-α,AND IFN-v IN ACUTE CORONARY SYNDROME

Objectives To explore serum cytokines levels (including IL-1 β, sIL-2R, IL-6, TNF-α, and IFN-v) and their significance in patients with acute coronary syndrome (ACS) and the subsequent follow-ups, with attempt to estimate the role of various serum inflammatory markers in the diagnosis and assessment of ACS.Methods The study population include 40 patients with acute myocardial infarction (AMI), 40 patients with unstable angina pectoris (UAP), and 40 controls. Among the 80 patients, 60 patients attended a follow up 4 months later. Serum inflammatory markers including IL-1 β, sIL-2R, IL-6, TNF-α, and IFN-v were measured by enzyme linked immunosorbent assay.Results Serum IL- 1 β, sIL-2R, IL-6, TNF-α were significantly higher in AMI group or UAP group compared to the control group and became significantly lower 4 months later in the follow-up patients. Serum levels of IFN-v shows no significant difference between AMI group or UAP group and controls, also showing no significant change when measured in follow up patients. There was no correlation between serum creatine kinase-MB isoenzyme levels and serum inflammatory markers either in UAP or AMI group. Furthermore, when divided into two subgroups using Wagner's QRS scoring system in the AMI group, there is no difference of each serum inflammatory marker between ≤ 6 scores group and ＞ 6 scores group.Conclusion Serum levels of certain inflammatory markers may have some diagnostic value for ACS, and can be a useful marker reflecting disease stability.