长期家庭氧疗对慢性阻塞性肺疾病患者心理情绪的影响

目的探讨长期家庭氧疗(LTOT)对慢性阻塞性肺疾病(COPD)低氧血症患者心理情绪的影响。方法 31例COPD低氧血症患者用医院焦虑和抑郁情绪表(HAD)进行心理情绪评分。然后分为LTOT组17例和对照组14例。LTOT组的氧流量0.5～2.5L/min,每日吸氧时间≥15h(包括睡眠时间);对照组除未进行LTOT外,其余治疗与氧疗组相同。两组年龄、性别、肺功能和动脉血气无明显差别。1年后分别复查HAD评分。结果 LTOT组焦虑评分由治疗前的14.35±3.81下降到1年后的9.65±3.83(P<0.01),抑郁评分由治疗前的13.18±4.50下降到1年后的9.06±2.79(P<0.01);对照组焦虑和抑郁评分均无明显变化。1年后LTOT组的焦虑及抑郁评分分别与对照组比较明显改善。1年后LTOT组除动脉血氧分压与对照组有显著差异外,动脉血二氧化碳分压、PH值及肺功能均无显著差异。结论 LTOT能改善COPD低氧血症患者的心理情绪。     

心理干预对慢性阻塞性肺病患者焦虑抑郁情绪的影响

目的　观察心理干预对慢性阻塞性肺病 (COPD)患者心理情绪的影响。方法　 10 0例 COPD患者分为心理干预组和对照组 ,两组均给予常规药物治疗 ,干预组增加心理干预 ,观察时间 1年 ,分别在干预前和 1年后应用医院焦虑抑郁(HAD)测评表评估患者心理情绪变化。结果　干预组焦虑评分由 9.88± 3.6 1降为 4.45± 3.38,抑郁评分由 10 .8± 4.0 3降为5 .36± 3.6 9。结论　心理干预能改善 COPD患者心理障碍 ,对 COPD的康复具有重要作用     

慢性阻塞性肺疾病患者长期家庭氧疗的临床观察

慢性阻塞性肺疾病(COPD)是可以引起劳动力丧失和死亡的常见慢性呼吸道疾病。严重COPD患者在缓解期仍存在低氧血症,长期家庭氧疗(LTOT)即每天在家里持续吸氧15h以上,使动脉血氧分压(PaO_2)>60 mm Hg(1 mm Hg=0.133 kPa)是COPD缓解期患者康复治疗的重要措施。本研究探讨LTOT对COPD患者生命质量(包括躯体功能、心理情绪)和肺功能的影响。     

慢性阻塞性肺疾病患者长期氧疗的疗效观察

目的观察慢性阻塞性肺疾病(COPD)患者长期氧疗(LTOT)的疗效.方法将64例COPD患者分成二组(非氧疗组和氧疗组),非氧疗组停止吸烟,常规给予抗感染、支气管扩张剂,祛痰药等治疗;氧疗组在以上常规治疗的基础上加长期氧疗,随访4年.结果LTOT可纠正低氧血压,减缓肺功能恶化,提高生活质量及降低死亡率.结论LTOT是COPD延长生命的重要途径.     

综合心理干预对慢性阻塞性肺疾病患者焦虑抑郁的应用研究

目的：探讨综合心理干预对慢性阻塞性肺疾病患者焦虑抑郁情绪的影响。方法：选取60例COPD患者,随机分为综合心理干预组和对照组,每组30例。两组给予常规抗炎、控制性氧疗、氨茶碱、祛痰及一般支持治疗;心理干预组在常规治疗基础上,由专业精神科医师团队进行专业心理干预。记录两组患者入院时及2周后心理量表及肺功能指标变化。结果：干预2周后综合心理干预组心理量表评分低于对照组（P＜0．05）,肺功能指标高于对照组（P＜0.05）。结论：综合心理干预能更好地改善COPD患者焦虑抑郁情绪,更利于肺功能的改善。     

CAT评分评价长期家庭氧疗在慢性阻塞性肺疾病并呼吸衰竭中的应用价值

目的应用慢性阻塞性肺疾病(COPD)评估测试量表(CAT)评分评价长期家庭氧疗(LTOT)在COPD并呼吸衰竭中的应用价值,并观察患者肺功能、动脉血气与CAT评分之间的相关性。方法将70例COPD患者随机分为对照组和氧疗组,每组35例,对照组予以常规治疗,氧疗组在常规治疗的基础上实施LTOT。对两组患者进行为期1 a随访,对比两组患者治疗前后肺功能、血气分析水平及与CAT评分的相关性。结果氧疗组患者肺功能FVC、FEV_1、FEV_1/FVC、动脉血气指标(SpO_2、PaO_2)显著高于治疗前及对照组,且其升高与CAT评分值成负相关,而PaCO_2下降与CAT评分值呈正相关。结论 LTOT可提高患者肺功能及血氧饱和度,显著降低患者CAT评分值,改善患者预后,提高生活质量;CAT评分可作为评价LTOT治疗效果的有效指标。     

积极护理干预对慢性阻塞性肺疾病患者抑郁情绪和生活质量的影响

目的:探讨积极护理干预对稳定期慢性阻塞性肺疾病(COPD)患者抑郁情绪和生活质量的影响。方法:选择2007年1月-2008年1月就诊确诊稳定期65例COPD患者,随机分为积极护理干预组(33例)和对照组(32例)。积极干预组随访1年,干预前和干预后1年分别采用抑郁自评量表和生活质量量表评估两组的抑郁情绪状态和生活质量。结果:积极护理干预后,COPD患者的抑郁情绪评分较对照组明显下降(39.6±7.9/59.6±8.9),生活质量总评分较对照组明显上升(78.8±4.5/62.1±10.4),P均<0.05。积极干预组患者1年后抑郁评分较干预前明显下降(55.6±15.2/39.6±7.9),生活质量总评分上升(63.9±14.7/78.8±4.5),P均<0.05。COPD患者抑郁情绪评分与生活质量评分呈负相关(r=-0.505,P<0.05)。结论:稳定期COPD患者存在着抑郁情绪障碍和生活质量下降,积极护理干预可以显著地改善患者的抑郁情绪状态,明显提高患者的生活质量。     

慢性阻塞性肺疾病患者伴焦虑抑郁的临床调查及治疗

目的:调查慢性阻塞性肺疾病(COPD)患者合并焦虑、抑郁的发生率,并探讨有效治疗COPD合并焦虑、抑郁患者的方案。方法:选择2018年1月-2019年1月在本院治疗的300例COPD患者,根据医院焦虑抑郁量表(HAD)评分统计COPD患者伴焦虑、抑郁的发生率;将COPD伴焦虑、抑郁患者按随机数字表法分为对照组和观察组。对照组采用COPD规范化治疗联合认知行为干预,观察组在对照组基础上给予草酸艾司西酞普兰治疗,比较两组治疗前后的HAD评分、肺功能、生活质量、呼吸困难评分及6分钟步行试验(6MWD)情况。结果:300例COPD患者中伴焦虑、抑郁60例,发病率为20.00%。治疗后,两组焦虑与抑郁评分均明显低于治疗前,且观察组均低于对照组(P0.05);治疗后,两组FEV1与FEV1/FVC%均高于治疗前,且观察组均高于对照组(P0.05)。治疗后,两组各项生活质量评分及总分均低于治疗前,且观察组均低于对照组(P0.05)。治疗后,观察组呼吸困难评分低于治疗前及对照组,且观察组6MWD情况优于治疗前与对照组(P0.05)。结论:COPD患者伴焦虑抑郁发生率较高,在COPD规范化治疗基础上应用草酸艾司西酞普兰联合认知行为干预能够有效改善COPD伴焦虑、抑郁患者的精神状态,有效改善患者的肺功能及生活质量,减轻呼吸困难程度,增强患者的运动能力。     

冠状动脉旁路移植患者术前心理状况对低氧血症发生的影响

目的 探讨冠状动脉旁路移植术（CABG）术后患者发生低氧血症的危险因素,以及术前心理状态对低氧血症发生的影响。方法 回顾性分析2018年6月至2021年10月入住本院心血管外科的成年患者,根据术后氧合指数将患者分为低氧血症组和非低氧血症组。采用医院焦虑抑郁量表评估患者的术前心理状态,当任一子量表评分大于7分时即认为存在焦虑抑郁状态,纳入心理障碍组,反之则纳入心理正常组。结果 本研究共纳入148例患者,其中45例术后出现低氧血症,发生率为30.4%。术前存在焦虑抑郁状态的患者共有70例,占47.3%。心理障碍组中低氧血症的发生率为40%(28/70),显著高于心理正常组的21.8%(17/78)(P<0.05)。术后24 h心理障碍组患者的氧合指数显著低于心理正常组（P<0.05）。年龄、术前合并慢性阻塞性肺病（COPD）、术前焦虑抑郁、手术时间被发现与低氧血症的发生密切相关（P<0.05）,而进一步通过logistics回归分析证实术前合并COPD、术前焦虑抑郁、手术时间是低氧血症发生的独立危险因素（P<0.05）。当CABG患者术前出现焦虑抑郁后,其机械通气时...     

长期家庭氧疗对慢性阻塞性肺疾病的治疗作用

目的　通过对一组伴严重低氧血症的COPD患者进行长期家庭氧疗 (LTOT) ,以了解该治疗的临床意义。方法　选择缓解期COPD患者 5 0例 (PaO2 <7 3kPa(5 5mmHg)或SaO2 <88% )进行家庭氧疗 2个月 ,氧疗前后进行血气分析和血细胞比容测定。结果　每日持续吸氧 >15h者的PaO2 升高同时不伴有PaCO2 的升高 ,血细胞比容较氧疗前明显下降 ,临床症状明显改善。结论　应对伴有严重低氧血症的COPD患者进行LTOT。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

Luo Lingjie's Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.