护理干预对儿童糖尿病患者的影响

目的:讨论护理干预对儿童糖尿病患者的影响。方法:选择2012年3月-2013年5月本院收治的I型糖尿病患儿共60例,按随机数字表法分为两组,观察组采用护理干预手段,对照组采用常规护理。比较两组治疗前后的空腹血糖、餐后2 h血糖、抑郁得分和焦虑得分及糖化血红蛋白,以评价护理干预的效果。结果:观察组治疗后的空腹血糖为(5.25±0.51)mmol/L、餐后2 h血糖为(7.16±0.77)mmol/L、抑郁得分为(13.2±3.8)分、焦虑得分为(7.2±1.8)分、糖化血红蛋白为(7.59±1.46)%,与对照组比较差异均有统计学意义(P0.05)。结论:护理干预可以有效提高糖尿病儿童患者的治疗效果,并促进心理健康发展。     

优质护理饮食干预对糖尿病肾病患者血糖、营养状况及肾功能的影响

目的:探讨优质护理饮食干预对糖尿病肾病患者血糖、肾功能及营养状况的影响。方法:选取86例糖尿病肾病患者为观察对象,按照随机数字表法将其分成对照组和观察组各43例。对照组患者实施常规护理,观察组患者在对照组基础上给予优质护理饮食干预。比较两组患者血糖水平、营养状况、肾功能变化情况。结果:(1)护理前,两组患者血糖水平差异无统计学意义(P>0.05);护理后,观察组与对照组患者空腹血糖、餐后2 h血糖、糖化血红蛋白水平较护理前皆有所改善,差异有统计学意义(P<0.05);护理后,观察组患者空腹血糖水平为(4.28±0.95)mmol/L,餐后2 h血糖水平为(6.18±1.66)mmol/L,糖化血红蛋白水平为(6.32±0.73)%,低于对照组的(6.63±1.36)mmol/L、(7.22±1.51)mmol/L、(7.85±0.92)%,差异具有统计学意义(P<0.05)。(2)护理前,两组患者欧洲营养风险筛查量表(NRS2002)评分差异无统计学意义(P>0.05);护理后,观察组NRS2002评分为(1.49±1.19)分,低于对照组的(1.98±1.07),差异具有统计学意义(P<0.05)。(3)护理前,两组患者CysC、BUN、Scr水平差异无统计学意义(P>0.05);护理后,观察组CysC水平为(0.79±0.16)mg/L,低于对照组的(0.85±0.09)mg/L,差异有统计学意义(P<0.05);护理后,观察组的BUN水平为(12.24±1.02)mmol/L、Scr水平为(95.23±10.14)μmol/L,高于对照组的(8.62±1.23)mmol/L、(88.52±11.19)μmol/L,差异具有统计学意义(P<0.05)。结论:优质护理饮食干预相较于常规护理,可有效降低糖尿病肾病患者血糖水平,改善患者的营养状况及肾功能,利于预后。     

老年糖尿病患者社区护理干预的效果

目的探究社区护理干预在老年糖尿病患者中的临床效果。方法选取我院2015年4月至2018年6月收治的老年糖尿病患者102例,平均分为对照组和观察组。对照组采用常规护理干预,观察组采用社区护理干预,对比分析两组患者的空腹血糖、餐后2 h血糖、糖化血红蛋白水平(HbAlc)以及不良反应发生率。结果干预后,观察组空腹血糖(6.08±0.92)mmol/L、餐后2h血糖(9.13±1.27)mmol/L、HbA1c(5.63±1.15)%以及不良反应发生率(5.88%)低于对照组[(7.16±0.86)mmol/L,(11.58±1.81)mmol/L,(6.78±1.24)%,(21.57%)],差异有统计学意义(P0.05)。结论对老年糖尿病患者实施社区护理干预能够在降低患者血糖水平的同时,保证其血糖指标的稳定性,减少不良反应的发生,在临床上值得推广和使用。     

饮食护理干预对糖尿病血糖控制的影响探讨

目的 探讨饮食护理干预对糖尿病血糖控制的影响.方法 选取来我院诊治的204例糖尿病患者,随机分为观察组与对照组各102例.对照组在基础治疗基础上给予常规护理,观察组在对照组基础上给予饮食护理干预.分析比较2组患者干预前及干预后2周、4周的空腹血糖、餐后2 h血糖、糖化血红蛋白等的变化情况及护理满意度.结果 干预后,2组患者的空腹血糖、餐后2 h血糖、糖化血红蛋白均有所下降,与干预前比较差异有统计学意义(P<0.05);但观察组干预后空腹血糖、餐后2 h血糖、糖化血红蛋白较对照组下降更显著,差异有统计学意义(P<0.05).观察组护理满意度为98.0%,明显高于对照组的88.2%,差异有统计学意义(P<0.05).结论 常规护理干预及饮食护理干预均能改善糖尿病患者的血糖状况,但饮食护理干预效果更好,值得在临床上进一步推广应用.     

营养护理干预联合中医辨证治疗糖尿病肾病的效果研究

目的:探讨营养护理干预对糖尿病肾病患者临床中医辨证治疗的预后影响。方法:选取2013年1月到2014年1月到我院就诊的糖尿病肾病患者共130例,将患者抽签随机分为两组各65例,两组患者均在西医分期的基础上运用中医辩证分型论治,观察组在常规基础上行营养护理干预,比较两组的血脂、肾功能等变化情况。结果:观察组患者的TC、TG及24h尿蛋白分别为(4.13±0.86)mmol/L、(1.46±0.32)mmo/L与(0.54±0.11)g/24h,与对照组比较均有显著下降,各项指标的组间差异具统计学意义(P0.05)。对照组空腹血糖为(4.52±0.42)mmol/L,餐后2h血糖为(6.42±1.02)mmol/L,糖化血红蛋白为(5.51±0.27)%,空腹胰岛素为(16.3±5.2)m U/L;观察组治疗后空腹血糖(5.41±1.32)mmol/L,餐后2h血糖(7.42±1.41)mmol/L,糖化血红蛋白为(5.83±0.52%,空腹胰岛素为(18.93±6.62m U/L。结论:营养护理干预联合中医辨证治疗糖尿病肾病有显著疗效,值得临床推广使用。     

临床护理路径应用在老年糖尿病患者实施饮食健康教育的效果分析

目的：探讨临床护理路径应用在老年糖尿病患者中对饮食健康教育的效果和应用价值。方法：选择我院治疗的老年糖尿病患者124例采用随机数字表法分为观察组和对照组,对照组给予常规健康教育,观察组采取临床护理路径模式进行饮食健康教育,记录两组护理效果。结果：观察组干预后空腹血糖（6．43±1．03）mmol ／L,餐后2h 血糖（9．34±1．81）mmol ／L,糖化血红蛋白（6．86±1．55）％,上述指标均低于对照组,差异有统计学意义（P ＜0．05）。结论：临床护理路径应用在老年糖尿病患者饮食健康教育中可以有效地降低患者空腹血糖和餐后2h 血糖,改善患者糖化血红蛋白,值得在临床上大力推广使用。     

生化指标在2型糖尿病中的临床应用价值探讨

目的 探讨生化指标在2型糖尿病中的应用价值。方法 选取南通市海门区中医院2020年12月—2021年9月收治的128例2型糖尿病患者作为观察组,同期128例健康人群作为对照组,比较2组受检者的空腹血糖、餐后2 h血糖、糖化白蛋白、糖化血红蛋白结果。结果 观察组空腹血糖（9.87±2.15）mmol/L,餐后2 h血糖（17.61±2.75）mmol/L,糖化白蛋白（32.72±3.45）%,糖化血红蛋白（9.96±2.32）%,均高于对照组空腹血糖（4.80±0.62）mmol/L,餐后2 h血糖（6.15±0.74）mmol/L,糖化白蛋白（12.31±1.28）%,糖化血红蛋白（4.72±0.61）%,具有明显差异（P<0.05）。观察组中,空腹血糖检出率为82.81%,餐后2 h血糖检出率为92.19%,糖化白蛋白检出率为84.38%,糖化血红蛋白检出率为95.31%,四项生化指标联合检出率为100%。观察组中,糖化血红蛋白<7.0%时,并发症发生率为5.00%;糖化血红蛋白7.0%～8.0%时,并发症发生率为12.00%;糖化血红蛋白8.0%～9.0%时,并发症发生...     

个体化综合护理干预对2型糖尿病患者自我管理能力及血糖水平的影响

目的 探讨个体化综合护理干预对2型糖尿病患者自我管理能力及血糖水平的影响.方法 选取2016年2～8月在海口市人民医院内分泌科住院治疗的2型糖尿病患者100例,应用糖尿病自我管理行为量表6(SDSCA-6)在干预前对患者进行评估,找出患者自我管理方面存在的问题,制定个体化综合护理干预方案.出院后电话随访6个月,比较综合护理干预前后患者的空腹血糖,餐后2h血糖、糖化血红蛋白以及饮食、运动、血糖监测、足部护理、用药自我管理评分.结果 综合护理干预6个月后,患者空腹血糖,餐后2h血糖、糖化血红蛋白分别从干预前的(10.86±4.16)mmol/L、(16.84±4.95)mmol/L、(8.19±1.77)％降至干预后的(6.64±0.68)mmol/L、(8.60±1.13)mmol/L、(7.43±1.12)％,差异均有显著统计学意义(P<0.01);饮食、运动、血糖监测、足部护理、用药自我管理评分均明显提高,与干预前比较,差异均有显著统计学意义(P<0.01);吸烟人数从干预前的15.0％下降至干预后的5.0％,差异有统计学意义(P<0.05).结论 对2型糖尿病患者进行个体化综合护理干预有助于提高患者的自我管理能力,改善血糖水平,值得临床推广.     

高校教职工糖尿病护理干预效果观察

目的:探讨护理干预对高校教职工糖尿病患者临床效果的影响。方法:对80例糖尿病患者在给予降糖药物的治疗的基础上进行健康教育、心理护理、饮食指导、运动指导和用药护理的护理干预。比较干预前后糖尿病患者体质指数、空腹血糖、餐后2h血糖、糖化血红蛋白(HbA1c)、收缩压、舒张压的变化情况。结果:研究发现干预后患者在体质指数、空腹血糖、餐后2h血糖、糖化血红蛋白(HbA1c)等方面的表现均优于干预前,差异有统计学意义(P<0.05)。结论:通过护理干预,糖尿病患者体质指数、空腹血糖、餐后2h血糖、糖化血红蛋白(HbA1c)等均有明显的改善,值得推广使用。     

团体认知护理模式对老年精神障碍伴糖尿病患者血糖水平的影响

目的研究团体认知护理模式对老年精神障碍伴糖尿病患者血糖水平的影响。方法选择2014年4月‐2015年4月在该院住院治疗的72例老年精神障碍伴糖尿病患者作为研究对象,随机分为两组,对照组采用常规护理模式进行护理,实验组采用团体认识护理模式进行护理。比较两组护理前后患者血糖控制情况。结果实验组进行团体认知护理模式后患者空腹血糖(FPG)、餐后2 h血糖(2h PG)及糖化血红蛋白(Hb A1c)分别为(6.7±1.2)mmol/L、(8.0±0.7)mmol/L及(6.8±1.4)%,显著低于护理干预前和对照组干预后,差异具有统计学意义(P0.05)。结论团体认知护理模式可有效控制老年精神障碍伴糖尿病患者的血糖水平,临床应用价值较高,值得推广。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

CLINICAL SIGNIFICANCE OF SERUM CYTOKINES IL-1β,sIL-2R,IL-6,TNF-α,AND IFN-v IN ACUTE CORONARY SYNDROME

Objectives To explore serum cytokines levels (including IL-1 β, sIL-2R, IL-6, TNF-α, and IFN-v) and their significance in patients with acute coronary syndrome (ACS) and the subsequent follow-ups, with attempt to estimate the role of various serum inflammatory markers in the diagnosis and assessment of ACS.Methods The study population include 40 patients with acute myocardial infarction (AMI), 40 patients with unstable angina pectoris (UAP), and 40 controls. Among the 80 patients, 60 patients attended a follow up 4 months later. Serum inflammatory markers including IL-1 β, sIL-2R, IL-6, TNF-α, and IFN-v were measured by enzyme linked immunosorbent assay.Results Serum IL- 1 β, sIL-2R, IL-6, TNF-α were significantly higher in AMI group or UAP group compared to the control group and became significantly lower 4 months later in the follow-up patients. Serum levels of IFN-v shows no significant difference between AMI group or UAP group and controls, also showing no significant change when measured in follow up patients. There was no correlation between serum creatine kinase-MB isoenzyme levels and serum inflammatory markers either in UAP or AMI group. Furthermore, when divided into two subgroups using Wagner's QRS scoring system in the AMI group, there is no difference of each serum inflammatory marker between ≤ 6 scores group and ＞ 6 scores group.Conclusion Serum levels of certain inflammatory markers may have some diagnostic value for ACS, and can be a useful marker reflecting disease stability.     

Possible Spread of adenovirus type 3 from poultry to humans ：indirect evidence from an outbreak in China

Objective:To explore the epidemiology and etiology for an outbreak of acute respiratory tract infection that occurred in one county of Jiangsu Province, China 2004. Methods: Only cases meeting the case definition were included in the study. We reviewed the medical records of the cases who were admitted to the local hospitals, interviewed cases by a standard questionnaire, and then described the epidemiotogic features and analyzed risk factors by means of a case-control study. We collected pharyngeal swab specimens and sent them to different laboratories for isolation and culture. The laboratory used different detection methods such as DIP, PCR, electron microscope examination and microneutralization assay, to identify and then type the positive specimens. Results:A total of 871 cases were reported during the period from April 18 to July 4,2004. The distribution of onset times presented two peaks, one in late May and another in middle June. The epidemic occurred mainly in the elementary and junior high schools in ten townships of one county, and the mean age of the cases was 12 years (range 7 months to 18 years). The course of the disease was acute, and was characterized by fever accompanied with sore throat and tonsillitis. The WBC count of cases was normal or elevated. The mean duration of illness was 5 days (range 2 to 12 days). No fatalities from illness were reported. A case-control study indicated that the possible risk factors were close contact with a case and/or poultry before onset and sharing of towels among members of the family. The typical CPE was observed through inoculating pharyngeal swab specimens into the HEP-2 cell cultures in different laboratories. An infection of adenovirus type 3 was verified by detecting positive specimens in different methods. Conclusion:This investigation demonstrated that the acute respiratory infection in cases was caused by adenovirus type 3. Cases occurred in over 70 schools in ten townships in 2004, and the route of transmission was possibly close contact with cases or droplet transmission.