脂肪肝危险因素与脂肪肝严重程度的相关因素分析

非酒精性脂肪性肝病是指除外酒精和其他明确损伤因素所致的,以弥漫性肝细胞大泡性脂肪变为主要特征的临床病理综合征.随着肥胖和糖尿病患病率的增加,脂肪肝已成为我国常见的慢性肝病之一,它通常与肥胖,胰岛素抵抗和内脏脂肪的堆积相关[1].此外,非酒精性脂肪性肝病还被认为是以内脏型肥胖、糖尿病、血脂异常和高血压为特征的代谢综合征的临床表现之一[2].内脏脂肪堆积是代谢综合征一个非常重要的危险因素[3].本研究旨在探讨成人内脏脂肪量及其他人体测量指标与脂肪肝及其严重程度的关系,分析脂肪肝的危险因素及影响其严重程度的相关因素,为脂肪肝的防治提供参考.     

非酒精性脂肪肝的流行病学

非酒精性脂肪性肝病(nonalcoholic fatty liver disease,NAFLD)俗称脂肪肝,是指以肝实质细胞脂肪变性为病理特征,而无过量饮酒史,又除外其他肝病的临床综合征,其病理类型包括单纯性脂肪肝、脂肪性肝炎(NASH)及NASH相关肝硬化,后者可发展为肝癌[1-3].NAFLD常与肥胖、2型糖尿病、血脂紊乱、高血压等代谢综合征(MS)症状并存,近年患病率呈逐年增加的趋势,已成为慢性肝病及血清氨基酸转移酶(下称转氨酶)水平升高的主要原因之一.     

脂肪肝

二氯醋酸二异丙胺治疗非酒精性脂肪性肝病的随机双盲临床研究；健脾法电针配合耳穴治疗肥胖性脂肪肝30例临床观察；老年2型糖尿病胰岛素抵抗与非酒精性脂肪肝相关分析；中药联合普伐他汀治疗代谢综合征合并脂肪肝55例临床观察；非酒精性脂肪性肝病发病时瘦素的变化。     

代谢综合征与脂肪肝

脂肪肝是遗传 环境 代谢应激相关因素所致的以肝细胞脂肪变性为主的临床病理综合征 ,病理上主要包括单纯性脂肪肝、脂肪性肝炎和脂肪性肝硬化三种类型 ,临床上则有酒精性脂肪性肝病和非酒精性脂肪性肝病 (ＮＡＦＬＤ)之分 ,目前日益增多的脂肪肝主要为与胰岛素抵抗 (ＩＲ)密切相关的ＮＡＦＬＤ。多数情况下 ,ＮＡＦＬＤ为ＩＲ综合征 肥胖综合征 代谢综合征的组成成分之一 ,纠正代谢紊乱可能有助于ＮＡＦＬＤ的防治。1　代谢综合征与脂肪肝的关系1.1　脂肪肝与代谢综合征　流行病学研究显示 ,ＮＡＦＬＤ与肥胖、糖耐量异常 (ＩＧＴ)和糖…     

性激素对脂肪肝性别差异之调节

随着社会老龄化以及病毒性肝炎等其他肝病的控制，与肥胖和代谢综合征相关脂肪性肝病已经成为严重的健康问题。目前认为，脂肪肝疾病谱包括单纯脂肪肝、脂肪性肝炎及其相关肝硬化，甚至肝细胞癌。在上述脂肪肝进展过程中，影响因素很多，例如，年龄、内脏性肥胖、基因缺陷、胰岛素抵抗等等。     

重视非酒精性脂肪性肝病的综合处理

非酒精性脂肪性肝病（NAFLD）是一种与胰岛素抵抗（IR）相关的代谢应激性肝病，其疾病谱包括单纯性脂肪肝、非酒精性脂肪性肝炎（NASH）及其相关肝硬化。2004年世界IR研讨会把NAFLD列入构成代谢综合征（MS）的主要条件，MS的其他组分包括内脏型肥胖、2型糖尿病、高脂血症和高血压等。     

非酒精性脂肪肝的西医治疗进展

<正>非酒精性脂肪性肝病(nonalcoholic fatty liver disease,NAFLD)是一种与胰岛素抵抗,糖尿病、肥胖等代谢危险因素密切相关的应激性肝脏损伤,其疾病谱包括非酒精性单纯性脂肪肝(nonalcoholic simple fatty liver,NAFL)、非酒精性脂肪性肝炎(nonalcoholic steatohepatitis,NASH)及其相关肝硬化和     

受控衰减参数在脂肪肝诊断中的应用

<正>脂肪性肝病(fatty liver disease,FLD)是以弥漫性肝细胞大泡性脂肪变为主要特征的临床病理综合征,主要包括酒精性肝病(alcoholic liver disease,ALD)和非酒精性脂肪性肝病(nonalcoholic fatty liver disease,NAFLD),疾病谱包括单纯性脂肪肝、脂肪性肝炎及其相关肝硬化[1]。随着肥胖、糖尿病和酒精滥用成为全球化的流行趋势,无论是NAFLD还是ALD都已成为重要的公共健康问题,并且酒精性和非酒精性FLD     

成扬运用升降散合小柴胡汤治疗非酒精性脂肪性肝病合并高脂血症经验探析

正非酒精性脂肪性肝病(NAFLD)是指除外酒精和其他明确的肝脏损害因素所致的,以弥漫性大细胞性脂肪变和肝细胞内脂肪过度沉积为主要特征的临床病理综合征,包括单纯性脂肪肝、脂肪性肝炎、脂肪性肝纤维化和肝硬化等,后者还可进展为肝细胞癌[1,2]。NAFLD是代谢综合征的肝脏表现的一个组成部分,它代表了心血管疾病发展的一个危险因素,独立于糖尿病、高血压和肥胖的存在[3]。流行病学调查显示,NAFLD在西方国     

非酒精性脂肪性肝病的临床特征

非酒精性脂肪性肝病(NAFLD)是一组肝脏病理学改变与酒精性肝病相似，但无过量饮酒史的临床综合征，包括单纯性脂肪肝、非酒精性脂肪性肝炎(NASH)和肝硬化等一系列改变。肥胖和糖尿病是NAFLD的主要危险因素，NAFLD特别是NASH患者通常伴有胰岛素抵抗(IR)和代谢综合征，IR可能为联系NAFLD病因和临床特征之间的桥梁。     

Research and Evaluation of the Influence of the Construction of the Gate and the Influence of the Piston Velocity on the Distribution of Gases into the Volume of the Casting

Distribution of gasses to the cast volume and volume of pores can be maintained within the acceptable limits by means of correct setting of technological parameters of casting and by selection of suitable structure and gating system arrangement. The main idea of this paper solves the issue of suitability of die casting adjustment—i.e., change of technological parameters or change of structural solution of the gating system—with regards to inner soundness of casts produced in die casting process. Parameters which were compared included height of a gate and velocity of a piston. The melt velocity in the gate was used as a correlating factor between the gate height and piston velocity. The evaluated parameter was gas entrapment in the cast at the end of the filling phase of die casting cycle and at the same time percentage of porosity in the samples taken from the main runner. On the basis of the performed experiments it was proved that the change of technological parameters, particularly of pressing velocity of the piston, directly influences distribution of gasses to the cast volume.     

县级以下综合医疗机构医务人员对现代结控知识的认识现状调查

目的本文旨在了解医务人员现代结控知识掌握的现状及培训效果?方法于培训前后进行问卷调查,内容包括:病例发现?结核病诊断及化疗?结果培训前疫情报告和转诊,回答正确者占75.2%?71.7%;对临床表现?查痰和诊断依据,回答正确者占83.5%?42.5%?40.8%;抗痨药物?用药方法?化疗原则?短化方案?短化疗程?治愈标准六项,回答正确者占58%?14.4%?20.8%?9.2%?17%?24.3%?培训后再次调查发现,90%以上医务人员对现代结控基本知识已掌握?结论各级医务人员现代结控知识是很贫乏的,因此,对其进行系统培训是极为必要的,此项工作省时?省力?投入少,可收到事半功倍的效果。     

Preservation of the pylorus and resection of the head of the pancreas

The historical evolution of the pylorus-preservation resection of the head of the pancreas is traced from the first resections early in this century to relative standardization of the operation, to a lowering of the operative mortality, and to an interest in improving nutritional status after resection. There are many theoretical advantages for the function of the upper gastrointestinal tract after pylorus and gastric preservation, such as maintenance of gastric capacitance and equilibration of osmotic pressure in gastric digestants, foodstuff digestion and absorption, and bowel motility. After the pylorus-preserving resection, gastric emptying is normal, pyloric function to prevent duodenal reflux is often normal, and gastric acids and serum levels of duodenal hormones are at normal levels, whereas after standard pancreatoduodenectomy, all of these are often abnormal. No prospective blinded studies have been published comparing nutritional values after the two operative procedures, but evidence is presented of a satisfactory result with regard to gastric capacitance, body weight gain, and lack of postgastrectomy symptoms. An undoubted advantage of the pylorus-preserving feature is a simplification of the operation. These gains are achieved without increase in operative mortality, without increase in the incidence of jejunal ulcer, and without theoretical or actual decrease in value of the procedure as a cancer operation, except in patients with duodenal carcinoma proximal to the ampulla of Vater.     

Preservation of the pylorus in resection of the head of the pancreas

Pylorus preservation has been advocated to decrease the morbidity associated with the classical or standard pancreaticoduodenectomy. The proposed advantages are decreased incidence of peptic ulceration, dumping syndrome, and nutritional problems. However, after an initial period of enthusiasm for the procedure, it is now being found that marginal ulceration at the duodenojejunal anastomosis is encountered with increasing frequency. Delay in gastric emptying occurs frequently, with an overall incidence of 30%. With the availability of better pancreatic enzyme supplements, the current incidence of nutritional problems and weight loss after the standard Whipple procedure is unknown. Whether there is a difference in long-term survival after the two procedures performed for adenocarcinoma of the head of the pancreas is still debatable. A controlled trial is needed to answer many of these questions, and pylorus-preserving pancreaticoduodenectomy should be used cautiously until further data become available.