外剥内扎痔核悬吊保留齿线术治疗环状混合痔临床观察

目的总结外剥内扎痔核悬吊保留齿线术治疗环状混合痔临床观察,为提高手术治疗环状混合痔的疗效,减少术后并发症。方法将120例环状混合痔患者随机分为2组,各60例。治疗组采用外剥内扎痔核悬吊保留齿线术,对照组采用传统外剥内扎术。结果 2组患者治愈率差异无统计学意义,P>0.05;但治疗组在术后疼痛、坠胀、水肿、肛周皮赘、肛门溢液及愈合时间等方面均明显优于对照组,P<0.05。结论外剥内扎痔核悬吊保留齿线术治疗环状混合痔创伤小,并发症少。疗效肯定。     

64例环状混合痔治疗体会

目的 观察原位皮瓣移植齿线保留术治疗环状混合痔的临床效果.方法 将64例环状混合痔的患者按病历号顺序随机分为原位皮瓣移植齿线保留术治疗组34例(A组)及外剥内扎术治疗组30例(B组),观察两组治愈时间、疼痛情况、肛门狭窄、水肿等术后并发症.结果 64例患者全部治愈,A组在治愈时间、术后疼痛、肛门狭窄、术后水肿等方面优于...     

保留齿状线内悬吊外切剥术治疗混合痔的临床研究

目的 探讨保留齿状线内悬吊外切剥术治疗混合痔的临床疗效.方法 将68例混合痔患者随机分为两组,治疗组(34例)采用保留齿线内悬吊外切剥术治疗,对照组(34例)采用外剥内扎硬注术治疗.观察两组患者疗效,术后并发症,术后肛门功能情况,手术时间,住院天数,切口愈合时间.结果 两组临床疗效相比差异无统计学意义(P>0.05);术后肛门疼痛、住院天数和切口愈合时间差异有统计学意义(P<0.05);术后肛门功能方面差异无统计学意义(P>0.05).结论 保留齿线内悬吊外切剥术能有效治疗混合痔,并且减轻术后并发症,缩短切口愈合时间及住院天数,是一种安全、有效、经济、适宜推广的治疗混合痔的新方法.     

改良分段剥扎注射加肛管皮桥悬吊法治疗环状混合痔180例疗效观察

目的:探讨改良分段剥扎注射加肛管皮桥悬吊法治疗环状混合痔的效果.方法:对180例环状混合痔作改良分段剥扎注射加肛管皮桥悬吊法(治疗组)与152例传统外剥内扎法(对照组)疗效结果对比观察.结果:治疗组在术后肛缘光滑率、疼痛率、水肿率及平均治愈时间都优于对照组(P＜0.05).结论:改良术式较传统外剥内扎术用于环状混合痔的治疗有较大优势.     

分段外切内套扎保留齿状线加注射治疗环状混合痔

为探讨治疗环状混合痔较理想的手术方法,将120例环状混合痔患者随机分为治疗组和对照组各60例,分别采用分段外切内套扎保留齿状线加注射和传统的外剥内扎术治疗,并进行疗效对比观察。结果显示,治疗组治愈率为93．3％,对照组治愈率为95．0％,两组比较无显著性差异（P〉0．05）。治疗组治愈时间为（17．3±3．4）d,对照组为（21．4±3．1）d,两组比较有显著性差异（P〈0．01）,治疗组在术后疼痛、水肿、出血、皮赘残留等方面均优于对照组（P〈0．05,P〈0．01）。结果表明,分段外切内套扎保留齿状线加注射治疗环状混合痔有较好的临床实用价值。     

悬吊结扎外剥加后位切开扩肛术治疗环状混合痔

为了提高环状混合痔的手术疗效,随机将120例环状混合痔分为治疗组（60例）和对照组（60例）。治疗组行保留肛垫悬吊结扎外剥加后位切开扩肛术,对照组行内扎外剥加后位切开扩肛术,观察术后恢复情况及并发症。结果显示,治疗组在术后疼痛,肛缘水肿,肛门漏液、漏气、狭窄,创口愈合时间,治愈率方面均优于对照组。结果表明,保留肛垫悬吊结扎外剥加后位切开扩肛术治疗环状混合痔疗效优于传统手术方法。     

外剥内缝扎术悬吊联合皮桥整形在环状混合痔中的应用体会

目的探讨外剥内缝扎悬吊术联合皮桥成形在环状混合痔中的应用价值。方法将650例环状混合痔患者随机分为治疗组(332例)和对照组(328例),治疗组行外剥内缝扎悬吊术联合皮桥成形,对照组行外剥内扎术,对比观察两组疗效、术后并发症、术后肛门功能、平均住院时间及创面愈合时间。结果两组治愈率、好转率、术后大出血、术后疼痛对比无统计学差异(P0.05);治疗组在术后肛门功能、肛门狭窄、水肿、赘皮残留、平均住院时间及创面愈合时间均优于对照组,有统计学差异(P0.05)。结论外剥内缝扎悬吊术联合皮桥成形治疗环状混合痔在保护肛门功能、减少术后并发症及缩短治疗周期等方面优于传统的外剥内扎术,值得推广应用。     

外剥内扎加皮桥整形切缝术治疗环状混合痔的临床观察

目的:观察外剥内扎加皮桥整形切缝术治疗环状混合痔的临床疗效。方法:采用外剥内扎加皮桥整形切缝术治疗环状混合痔80例为治疗组,与常规外剥内扎术治疗环状混合痔60例为对照组进行对照观察。结果:两组治愈率比较,治疗组与对照组比较有显著性差异(P<0·01);两组术后并发症比较,治疗组与对照组比较有显著差异(P<0·01)。结论:外剥内扎加皮桥整形切缝术治疗环状混合痔疗效满意、术后并发症少。     

分段外剥内扎保留齿状线加肛垫悬吊术治疗环状混合痔36例临床观察

为避免过多损伤肛垫,保护齿状线功能,提高外科手术治疗环状混合痔的疗效,减少并发症和后遗症,采用分段外剥内扎保留齿状线加肛垫悬吊术治疗环状混合痔36例。结果显示,治愈33例（91．7％）,好转3例（8．3％）,有效率100％。随访半年,均无复发,无肛门狭窄及肛门失禁,肛门功能正常。结果表明,分段外剥内扎保留齿状线加肛垫悬吊术对肛垫及肛管皮肤损伤小,保留了齿状线的功能,对患者排便反射功能影响小,治疗比较彻底,并发症及后遗症少,临床疗效满意。     

外剥内扎加点状剥离治疗环状混合痔142例

目的:探讨外剥内扎母核、点状剥离继发性内痔治疗环状混合痔的临床效果.方法:将环状混合痔患者随机分为治疗组142例,行外剥内扎母核加点状剥离继发性内痔治疗;对照组138例,仅行外剥内扎母核治疗,比较两组疗效.结果:治疗组均一次性手术治愈或好转,治愈率与对照组有统计学差异,肛门功能评定有统计学差异.结论:外剥内扎母核加点状剥离继发性内痔术治疗环状混合痔,效果好,治愈率高,并发症少.     

胸腰椎骨折椎弓根内固定断裂与植骨融合方式的相关性分析

[目的]探讨胸腰椎骨折椎弓根螺钉内固定系统内固定术后,椎弓根螺钉断裂与植骨融合方式之间的关系,以探讨胸腰椎骨折植骨融合的最佳方式。[方法]回顾性研究1995年5月~2005年12月本院脊柱外科收治的胸腰椎骨折病人197例,其中A组单纯内固定(不植骨)患者14例,B组“H”形椎板植骨21例,C组横突间植骨67例,D组椎间、椎内联合横突间植骨95例。[结果]术后随访6~32个月,内固定断裂12例,其中A组4例,B组3例,C组5例,D组0例,4组中D组内固定断裂率显著低于其他3组(P<0.05)。[结论]椎间、椎体内联合横突间植骨重建脊柱三柱的稳定性,符合人体生物力学原理,能有效降低内固定断裂的发生。     

On the measurement of the functional properties of the CFTR

A number of methods are currently employed to assess the functional properties of CFTR channels and their response to pharmacological potentiators, correction of the defective CFTR trafficking, and vectorial introduction of new proteins. Here we review the most common methods used to assess CFTR channel function. The suitability of each technique to various experimental conditions is discussed.     

The Measurement of the Inclination Angle of the Hamate and Analysis of the Inclination Angle for the Rotation Deformity of the Little Finger in the Fixation of the Carpometacarpal Joint

ObjectiveComplex base fractures of the fifth metacarpal bone and dislocation of the fifth carpometacarpal joint are more prone to internal rotation deformity of the little finger sequence after fixation with a transarticular plate. In the past, we have neglected that there is actually a certain angle of external rotation in the hamate surface of transarticular fixation. This study measured the inclination angle of the hamate surface relative to the fifth metacarpal surface for clinical reference.MethodsIn a prospective single‐center study, we investigated the tilt angle of 60 normal hamates. The study included thin‐layer computed tomography (CT) data from 60 patients from the orthopaedic clinic and inpatient unit from January 2017 to March 2020, including 34 men and 26 women who were 15~59 years old, average 35 years old. The CT data of 60 cases in Dicom format of the hand was input into Mimics and 3‐Matics software for three‐dimensional (3D) reconstruction and measuring the angle α between hamate surface and the fifth metacarpal surface. According to the possible placement of the transarticular plate on the fifth metacarpal surface, we measured the angle β between the hamate surface 1 and the fifth metacarpal surface and the angle γ between the hamate surface 2 and the fifth metacarpal surface.ResultsThe average angle between the hamate surface and the fifth metacarpal surface was 11.66°. The hamate surfaces 1 and 2 have an external rotation angle of 7.30° and 7.51° on average with respect to the fifth metacarpal surface, respectively. There is no statistically significant difference in the angles between the two groups (P > 0.05).ConclusionsThe horizontal angle of the dorsal side of the hamate is different from the back of the fifth metacarpal surface, and the hamate has a certain external rotation angle with respect to the fifth metacarpal surface. No matter how the transarticular plate is placed, the plate always has a certain external rotation angle relative to the fifth metacarpal surface. When the fixation is across the fifth carpometacarpal joint, if the plate does not twist and shape, it will inevitably cause internal rotation of the fifth metacarpal, resulting in internal rotation deformity of the little finger sequence.     

静脉输注甘露醇开放血脑屏障对抗生素透过血脑屏障的影响

目的　通过快速静脉输注甘露醇可逆性开放血脑屏障 (BBB) ,探知此方法能否增加抗生素透过BBB的量 ,在何时达到最高峰 ,其通透量增加后临床上有无不良反应。方法　采用自身配伍设计 ,共 6个样本组。对照组仅使用抗生素 ;其余 5组分别在使用甘露醇前 60、3 0min ,同时使用甘露醇后 3 0、60min使用抗生素 ,各组皆取使用抗生素后 1h的脑脊液测其抗生素浓度。抗生素选用头孢三嗪。结果　测量值经过q检验 ,经 2 0 %甘露醇处理前后的CSF中的头孢三嗪浓度差异有非常显著性。全组患者经临床观察未出现神经系统的不良反应。结论　经静脉快速输注2 0 %甘露醇后可以使透过BBB的水溶性抗生素的量增加 ,两者使用的顺序是在抗生素使用 3 0min内即给予甘露醇快速滴注。该方法不会增加低神经毒性抗生素在中枢神经系统的不良反应。     

三角韧带损伤的手术治疗

[目的]探讨踝关节三角韧带损伤的手术治疗及效果。[方法]2002年4月-2005年4月治疗伴有三角韧带损伤的踝关节骨折40例，均采用切开复位和坚强内固定，并修复重建三角韧带，恢复踝关节内外侧结构的稳定性。下胫腓联合分离仍不稳定者，给予皮质骨螺钉横向内固定。[结果]全部病例得到16个月-3a随访，平均1．5a。按齐氏疗效评定标准：优良30例，可8例，差2例，优良率75％。[结论]强调踝关节骨折切开解剖复位，坚强内固定的同时，应充分重视修复重建三角韧带。     

Preservation of the pylorus and resection of the head of the pancreas

The historical evolution of the pylorus-preservation resection of the head of the pancreas is traced from the first resections early in this century to relative standardization of the operation, to a lowering of the operative mortality, and to an interest in improving nutritional status after resection. There are many theoretical advantages for the function of the upper gastrointestinal tract after pylorus and gastric preservation, such as maintenance of gastric capacitance and equilibration of osmotic pressure in gastric digestants, foodstuff digestion and absorption, and bowel motility. After the pylorus-preserving resection, gastric emptying is normal, pyloric function to prevent duodenal reflux is often normal, and gastric acids and serum levels of duodenal hormones are at normal levels, whereas after standard pancreatoduodenectomy, all of these are often abnormal. No prospective blinded studies have been published comparing nutritional values after the two operative procedures, but evidence is presented of a satisfactory result with regard to gastric capacitance, body weight gain, and lack of postgastrectomy symptoms. An undoubted advantage of the pylorus-preserving feature is a simplification of the operation. These gains are achieved without increase in operative mortality, without increase in the incidence of jejunal ulcer, and without theoretical or actual decrease in value of the procedure as a cancer operation, except in patients with duodenal carcinoma proximal to the ampulla of Vater.     

下颌全牙弓后移量及最后界的测量

目的：研究下颌牙弓的有效后移量及找寻下颌牙弓移动的后界。方法：选取涉及拔除下颌第三磨牙或下颌第三磨牙缺失的病例18例（男6例,女12例）。采用种植支抗牵引下牙弓向远中,治疗完成时所有病例均明确到达下颌牙弓后界,即下颌第二磨牙远中到达下颌升支前缘软组织交界处。应用治疗前后的曲断片测量下颌第二磨牙远中到升支前缘的距离。结果：下颌第二磨牙后移量为（3.49±1.21）mm;治疗后磨牙后间隙的长度为（4.43±0.97）mm。结论：下颌牙弓可确定性地实现整体后移;最大后移量由磨牙后间隙的长度决定;其最后界止于下颌第二磨牙远中与下颌升支前缘软组织交界处。