丁苯酞胶囊联合长春西汀治疗后循环缺血性眩晕的疗效观察

目的:观察丁苯酞胶囊联合长春西汀注射液治疗后循环缺血(PCI)性眩晕的临床疗效和安全性.方法:将80例后循环缺血患者随机分为对照组40例和治疗组40例.对照组给予长春西汀注射液治疗,治疗组给予丁苯酞胶囊联合长春西汀注射液治疗;两组给予口服阿司匹林肠溶片片等基础治疗相同,并观察比较两组的临床疗效.结果:治疗组总有效率97.5％,对照组总有效率82.5％,两组治疗后总有效率比较,差异有统计学意义(P＜0.05).治疗组在治疗过程中未出现明显不适反应.结论:丁苯酞胶囊联合长春西汀注射液治疗后循环缺血性眩晕安全有效.     

天麻素注射液联合长春西汀治疗后循环缺血性眩晕的临床效果

目的观察天麻素注射液联合长春西汀治疗后循环缺血性眩晕(PCIV)的临床效果。方法采用随机数表法将2018年3月至2019年3月在汝州市第一人民医院就诊的118例PCIV患者分为对照组和观察组,各59例。对照组接受长春西汀治疗,观察组加用天麻素注射液。对比两组治疗前后DHI评分、椎动脉和基底动脉的平均血流速度水平以及血浆黏度、红细胞比容水平;统计不良反应发生率。结果观察组治疗后DHI评分低于对照组(P<0.05);观察组治疗后左椎动脉、右椎动脉、基底动脉收缩期平均血流速度水平高于对照组(均P<0.05);观察组治疗后血浆黏度、红细胞比容水平低于对照组(均P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论天麻素注射液联合长春西汀治疗PCIV临床效果较好,且不会增加用药风险,具有临床推广价值。     

钩泽合剂智能颗粒剂型治疗肝阳上扰型梅尼埃病急性期临床研究

目的 :观察钩泽合剂智能颗粒剂型治疗肝阳上扰型梅尼埃病患者的临床疗效。方法 :将60例符合标准的梅尼埃病患者随机分为治疗组30例和对照组30例。治疗组以钩泽合剂智能颗粒剂型冲服,对照组以钩泽合剂中药饮片剂型水煎服。比较两组患者就诊时和治疗第7天时梅尼埃病四联征的模拟视觉评分(VAS)、纯音听阈测定结果、7 d内发作次数及持续时间。结果 :梅尼埃病四联症VAS评分中眩晕、耳聋、耳胀闷感症状治疗组改善程度优于对照组(P0.05),纯音听阈测定结果改善状况治疗组优于对照组(P0.05),发作持续时间及发作次数治疗组均少于对照组(P0.05)。结论 :钩泽合剂智能颗粒剂型治疗肝阳上扰型梅尼埃病急性期具有一定优势,值得临床推广。     

长春西汀联合银杏叶提取物治疗突发性耳聋的疗效观察

目的观察长春西汀联合银杏叶提取物治疗突发性耳聋的临床疗效。方法选取2015年1月~2016年1月就诊于我院的突发性耳聋患者96例,随机分为治疗组和对照组,每组48例。两组均予常规治疗,对照组在常规治疗的基础上加用银杏叶提取物,治疗组在上述治疗的基础上联合应用长春西汀治疗14 d。比较两组患者治疗前后的纯音测听结果及临床效果。结果治疗结束后,治疗组和对照组的总有效率分别为79.2%和62.5%,两组比较差异有统计学意义(P0.05)。治疗后,治疗组和对照组的纯音测听结果较治疗前明显改善(P0.05);治疗后,治疗组较对照组改善更明显(P0.05)。结论长春西汀联合银杏叶提取物对突发性耳聋具有较好的临床疗效,能明显提高听力,值得临床推广使用。     

苯海拉明联合长春西汀治疗眩晕症的临床疗效探究

目的对苯海拉明联合长春西汀在眩晕症治疗中的应用效果进行探究。方法选取2017年12月至2019年7月间诊治的80例眩晕症患者,对照组采用长春西汀进行治疗,观察组则在对照组基础上,加用苯海拉明进行治疗,对比两组患者的治疗效果。结果在本次研究中,观察组患者在采用苯海拉明联合长春西汀进行治疗后,患者的总有效率达到95%,对照组的总有效率仅为80%,差异显著,P0.05。结论在目前对眩晕症患者进行治疗的过程中,在采用苯海拉明联合长春西汀进行治疗后,患者的总有效率得到了显著的改善,同时降低了患者的眩晕评分,对各项眩晕症状进行迅速的缓解,临床推广价值较高。     

盐酸法舒地尔联合长春西汀治疗后循环缺血性眩晕的临床疗效及安全性分析

目的:观察盐酸法舒地尔联合长春西汀治疗后循环缺血性眩晕的临床疗效及安全性。方法:选取2013-2016年在我院诊断为后循环缺血性眩晕的患者50例,随机分为治疗组和对照组,每组25例。治疗组采用盐酸法舒地尔联合长春西汀注射液。对照组仅采用长春西汀注射液。疗程14天,观察临床症状改善情况,采用TCD检测两组的椎基底动脉血流速度。结果:治疗组的治疗总有效率为92%,高于对照组的72%(P0.05)。治疗组的基底动脉平均血流速度由(39±9)cm/s提高到(59±6)cm/s,对照组由(40±3)cm/s提高到(42±2)cm/s,两组差异有统计学意义(P0.05)。结论:盐酸法舒地尔联合长春西汀能显著改善后循环缺血性眩晕的相关临床症状。     

镇肝熄风汤辅助治疗椎-基底动脉供血不足性眩晕的疗效评价

目的：探究镇肝熄风汤加减联合天麻素注射液及长春西汀治疗椎-基底动脉供血不足性眩晕患者的疗效。方法：选取我院120例椎-基底动脉供血不足性眩晕患者（2019年1月至2021年1月）,按照随机数字表法分为观察组（n=60）和对照组（n=60）,对照组采用天麻素注射液及长春西汀治疗,观察组在对照组基础上采用镇肝熄风汤加减治疗。比较两组疗效、治疗前后中医证候积分、椎-基底动脉血流动力学[搏动指数（PI）、平均血流速度（Vm）]、血清降钙素基因相关肽（CGRP）、内皮素-1(ET-1)水平。结果：观察组总有效率（93.33%）较对照组（80.00%）高（P<0.05）;治疗后,观察组中医证候积分、PI、ET-1水平较对照组低,椎动脉、基底动脉Vm较对照组快,血清CGRP水平较对照组高（P<0.05）。结论：镇肝熄风汤加减联合天麻素注射液及长春西汀治疗椎-基底动脉供血不足性眩晕效果显著,可有效改善眩晕症状,调节血清CGRP、ET-1水平,增加脑血流量。     

长春西汀联合依达拉奉治疗脑梗死后血管性认知障碍疗效分析

目的观察脑梗死后血管性认知障碍者临床使用依达拉奉、长春西汀治疗的有效性。方法选取我院2014年7月~2016年10月期间收治的84例脑梗死后血管性认知障碍者,按随机排列表法分为两组,其中对照组41例(应用依达拉奉)、观察组43例(加用长春西汀)。疗程结束后对患者智能状态、认知功能进行评分并与治疗前进行比较,评估患者神经功能缺损情况以及预后情况,观察两组患者认知障碍治疗效果,统计治疗期间不良事件发生情况。结果观察组不良事件发生率为4.7%,与对照组的2.4%比较,组间差异无统计学意义(P0.05);智能精神状态检查量表(MMSE)、蒙特利尔认知评估表(Mo CA)评分入院时两组差异无统计学意义(P0.05),用药后观察组评分高于对照组(P0.05);治疗前NIHSS评分组间差异无统计学意义(P0.05),治疗后两组评分均有明显降低,且疗后7 d、1个月研究组评分低于对照组(P0.05);观察组总有效率为95.3%,相比于对照组的85.4%,观察组治疗效果更佳(P0.05);治疗后7 d、1个月研究组m RS低于对照组(P0.05)。结论脑梗死后血管性认知障碍者临床以依达拉奉、长春西汀联合治疗,患者认知障碍、神经功能、智能状态改善明显,临床治疗效果理想、预后情况好、用药安全性高。     

天麻素联合长春西汀治疗老年椎基底动脉供血不足的临床研究

目的探讨天麻素联合长春西汀治疗老年椎基底动脉供血不足的的临床疗效。方法选取该院神经科于2011年1月-2012年12月收治的老年椎基底动脉供血不足患者120例,作为该研究的对象。依据治疗方案选择不同,随机分为实验组（天麻素联合长春西汀治疗组）和对照组（长春西汀治疗组）两组,每组各60例患者。治疗结束后,统计两组治疗疗效及并发症发生情况,借此探讨天麻素联合长春西丁治疗老年椎基底动脉供血不足的的临床疗效及安全性。结果治疗结束后,实验组患者总有效率显著高于对照组患者,比较结果差异有统计学意义（P〈O．05）;两组患者均未出现严重并发症。结论天麻素联合长春西汀治疗老年椎基底动脉供血不足疗效显著,安全『生高,可以在临床上推广应用。     

二联药物方案对BPPV管石复位后残余眩晕患者临床症状及负面情绪的影响

目的 探讨联合药物方案对良性阵发性位置性眩晕(BPPV)管石复位后残余眩晕患者临床症状及负面情绪的影响。方法 回顾性分析我院收治的BPPV管石复位后残余眩晕患者共78例临床资料,其中单纯采用倍他司汀治疗43例设为对照组,在倍他司汀基础上联用利多卡因治疗35例设为观察组;比较两组眩晕症状消失时间、治疗前后DHI量表评分、SAS量表评分、SDS量表评分及随访复发情况。结果 观察组眩晕症状消失时间显著少于对照组(P<0.05);观察组患者治疗后1周、2周及3周DHI量表评分均显著低于对照组、治疗前(P<0.05);观察组患者治疗后3周SAS和SDS量表评分均显著低于对照组、治疗前(P<0.05);两组患者均随访3个月,未见复发病例。结论 联合药物方案治疗BPPV管石复位后残余眩晕可有效缩短起效时间,提高眩晕症状控制效果,并有助于缓解负面情绪。     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

Luo Lingjie's Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.