白内障超声乳化吸出术联合人工晶体植入术的初步报告

目的：评价白内障超声乳化吸出术联合人工晶体植入术的临床效果。方法：对２６例（２９只眼）老年性白内障患者施行白内障超声乳化吸出和后房型人工晶体植入术。结果：术后１周及３个月时,裸眼或球镜矫正视力≥０．５者２４只眼（８２．８％）,术后３个月视力≥１．０者１４只眼（４８．３％）。平均散光在术后１周和３个月时分别为（１．２５±０．５０）ｍ１和（０．７５±０．２５）ｍ１。明显低于对照组（Ｐ＜０．０１）。主要并发症有虹膜咬伤、后囊膜破裂、角膜明显水肿及后发障。结论：白内障超声乳化吸出术在术后散光控制和尽快恢复视力等方面明显优于囊外摘除术     

糖尿病患者白内障手术的疗效分析

目的分析白内障现代囊外摘除人工晶体植入术和超声乳化白内障吸除人工晶体植入术治疗糖尿病性白内障的疗效及并发症。方法选择2001年1月．2006年1月期间确诊为糖尿病白内障患者55例（68眼），51眼Ⅱ．Ⅲ级核，采用超声乳化白内障吸除后房型人工晶体植入术；17眼Ⅳ．Ⅴ级核，采用现代白内障囊外摘除后房型人工晶体植入术。结果55例（68眼）糖尿病患者白内障术后视力均有不同程度的提高，其中58眼（85．29％）术后1wk裸眼视力≥0．4。术中术后主要并发症经处理对术后视力无影响。结论对糖尿病性白内障患者采取恰当的术式,施行白内障现代囊外摘除人工晶体植入术或超声乳化白内障吸除人工晶体植入术疗效肯定。     

无后囊的后房型人工晶体缝线固定术

目的：评价后房型人工晶体（ＩＯＬ）缝线固定术的疗效。方法：４０例（４１只眼）无后囊膜的无晶体眼，外伤性白内障或白内障囊外摘除后囊膜破损＞５ｍｍ、晶体半脱位，施行后房型ＩＯＬ缝线固定术。结果：本组４１只眼手术均获成功，术后随访４～１８月。裸眼视力≥０．４者３５眼，占８５．３７％；≥０．１者６眼，占１４．６３％。术后３６眼ＩＯＬ居中，１眼轻度偏心，４眼轻度倾斜。结论：无后囊的后房型ＩＯＬ缝线固定术，是一种安全理想的方法。     

白内障超声乳化术中后囊破裂的后房型人工晶体植入术

目的：评价白内障超声乳化术中后囊破裂的I期后房型人工晶体植入术的疗效。方法：对231例（269眼）施行的白内障超声乳化术中后囊破裂39例（40眼）行I期后房型人工晶体植入术。结果：囊袋内植入12眼，人工晶体光学部前囊固定13眼，睫状沟内植入13眼，2眼需缝线固定，随访1－37个月，裸眼视力≥0．5者33眼（82．5％），≥1．0者19眼（47．5％），矫正视力≥0．5者38眼（95％），≥1．0者25眼（62．5％），并发症主要有：人工晶体偏位3眼，瞳孔变形2眼，结论：白内障超声乳化术中后囊破裂时，控制破口的扩大，利用前，后囊作支撑，结合前段玻璃体切割术，植入后房型人工晶体仍可取得满意的效果。     

高度近视并发白内障超声乳化吸出加人工晶体植入术的临床观察

目的：观察高度近视白内障患者行超声乳化吸出加人工晶体植入术的治疗效果。方法：回顾我院自2000年-2006年对高度近视并发白内障者42例（81眼）实施超声乳化＋人工晶体植入术，术后随访均在1年以上。结果：术中后囊破裂1眼，术后无1例出现并发症，术后1个月视力≥0．4者39眼（48．15％），≥0．1者72眼（88．89％），〈0．1者9眼（11．11％）。结论：高度近视并发白内障患者行超声乳化吸出加人工晶体植入术能有效的提高患者视力，同时低度数或负值后房型人工晶体又可进行屈光矫正，手术安全，疗效可靠。     

白内障超声乳化折叠式人工晶体植入与硬性人工晶体植入结果分析

目的：探讨白内障超声乳化折叠式人工晶体植入的优越性。方法：对５０例（５０只眼）老年性白内障行怕乳化吸出,通过３．２ｍｍ隧道切口植入硅胶折叠式人工晶体及４４例３．２ｍｍ切口基础上扩大至６．０－６．５ｍｍ,植入后房型ＰＭＭＡ硬性人工晶体。结果：术后１周裸眼视力≥０．５者占７８％。随访１－３个月视力≥０．８者占８６％,与后房型硬性人工晶体植入比较术后１和１个月平均散光分别为（０．９２±０．８４）ＤＴ （     

白内障超声乳化摘除人工晶体植入术的临床观察

目的：探讨白内障超声乳化摘除人工晶体植入术的临床疗效。方法：对216例（240只眼）老年人、并发症，外伤性和先天性白内障施行超声乳化摘除及后房型人工晶体植入术。结果：白内障超声乳化术后1周裸眼视力≥0.5者占72.9%,≥1.0者占54.2%,术后3-12个月矫正视力≥0.5者占93.8%,≥1.0者占77.5%。手术并发症主要为术后角膜水肿28只眼，后发障6只眼，术中后囊膜破裂6只眼，结论：白内障超声乳化摘除人工晶体植入术，切口小、手术时间短，视力恢复快，值得临床推广普及。     

晶体囊张力环在晶体半脱位超声乳化术中的应用

目的探讨晶体囊张力环（Capseular tension ring，CTR）植入晶体半脱位的囊袋内进行超声乳化白内障吸出术的安全性。方法对我院2001～2007年间10例晶状体半脱住患者实施白内障超声乳化摘除术，术中采用连续环形撕囊后植入晶体囊张力环，然后常规超声乳化摘除白内障，植入后房型人工晶体。结果9例术后人工晶体位置良好，无偏住。1例明显偏位。矫正视力术后2周〉0．8者2眼，0．5～0．8者5眼，0．1～0．4者2眼。并发症1眼高眼压，2例玻璃体脱出。1例人工晶体取出，植入前房型人工晶体。结论晶状体囊张力环是超声乳化白内障吸除术治疗白内障合并晶状体半脱位患者的新型辅助工具，它在提高手术安全性，防止人工晶体偏位，减少手术并发症方面具有重要意义。     

外伤性白内障超声乳化吸出与晶体植入术临床分析

探讨外伤性白内障障超声乳化吸出与人工晶体植入术的效果。方法对５２例５２眼外伤性白内障病人进行了超声乳化吸出，人工晶体植入术。结果术后随访４－２９月，视力≥０．５有４４例，０．１－０．４有５例，≤０．１有３例。结论外伤性白内障用超声乳化吸出与人工晶体植入术的处理方法，大大提高了手术效果，是一种很好的治疗方法。     

后房型人工晶体植入术41眼分析报告

本报道白内障现代囊外法除术联合Ｉ期后房型人工晶体植入术４１眼。其中老年性白内障３３眼，并发性白内障５眼，外伤性白内障２眼，并发球内异物取出１眼，术后随访半年以上２９眼，矫正视力≥０．５占随访总数的８９．６５％，表明，后房型人工晶体植入术是一种安全而有效的手术方法，在基层医院值得广泛推广。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

CLINICAL SIGNIFICANCE OF SERUM CYTOKINES IL-1β,sIL-2R,IL-6,TNF-α,AND IFN-v IN ACUTE CORONARY SYNDROME

Objectives To explore serum cytokines levels (including IL-1 β, sIL-2R, IL-6, TNF-α, and IFN-v) and their significance in patients with acute coronary syndrome (ACS) and the subsequent follow-ups, with attempt to estimate the role of various serum inflammatory markers in the diagnosis and assessment of ACS.Methods The study population include 40 patients with acute myocardial infarction (AMI), 40 patients with unstable angina pectoris (UAP), and 40 controls. Among the 80 patients, 60 patients attended a follow up 4 months later. Serum inflammatory markers including IL-1 β, sIL-2R, IL-6, TNF-α, and IFN-v were measured by enzyme linked immunosorbent assay.Results Serum IL- 1 β, sIL-2R, IL-6, TNF-α were significantly higher in AMI group or UAP group compared to the control group and became significantly lower 4 months later in the follow-up patients. Serum levels of IFN-v shows no significant difference between AMI group or UAP group and controls, also showing no significant change when measured in follow up patients. There was no correlation between serum creatine kinase-MB isoenzyme levels and serum inflammatory markers either in UAP or AMI group. Furthermore, when divided into two subgroups using Wagner's QRS scoring system in the AMI group, there is no difference of each serum inflammatory marker between ≤ 6 scores group and ＞ 6 scores group.Conclusion Serum levels of certain inflammatory markers may have some diagnostic value for ACS, and can be a useful marker reflecting disease stability.     

Possible Spread of adenovirus type 3 from poultry to humans ：indirect evidence from an outbreak in China

Objective:To explore the epidemiology and etiology for an outbreak of acute respiratory tract infection that occurred in one county of Jiangsu Province, China 2004. Methods: Only cases meeting the case definition were included in the study. We reviewed the medical records of the cases who were admitted to the local hospitals, interviewed cases by a standard questionnaire, and then described the epidemiotogic features and analyzed risk factors by means of a case-control study. We collected pharyngeal swab specimens and sent them to different laboratories for isolation and culture. The laboratory used different detection methods such as DIP, PCR, electron microscope examination and microneutralization assay, to identify and then type the positive specimens. Results:A total of 871 cases were reported during the period from April 18 to July 4,2004. The distribution of onset times presented two peaks, one in late May and another in middle June. The epidemic occurred mainly in the elementary and junior high schools in ten townships of one county, and the mean age of the cases was 12 years (range 7 months to 18 years). The course of the disease was acute, and was characterized by fever accompanied with sore throat and tonsillitis. The WBC count of cases was normal or elevated. The mean duration of illness was 5 days (range 2 to 12 days). No fatalities from illness were reported. A case-control study indicated that the possible risk factors were close contact with a case and/or poultry before onset and sharing of towels among members of the family. The typical CPE was observed through inoculating pharyngeal swab specimens into the HEP-2 cell cultures in different laboratories. An infection of adenovirus type 3 was verified by detecting positive specimens in different methods. Conclusion:This investigation demonstrated that the acute respiratory infection in cases was caused by adenovirus type 3. Cases occurred in over 70 schools in ten townships in 2004, and the route of transmission was possibly close contact with cases or droplet transmission.