63例老年冠心病患者无症状性心肌缺血的动态心电图监测

目的评价动态心电图对老年冠心病患者无症状心肌缺血（SMI）的诊断价值。方法对63例老年冠心病患者进行DCG监测。结果49例有529阵次缺血发作,其中38例（占77．6％）为无症状心肌缺血,上午6：00-12：00SMI的发作频率最高（57．8％）。结论SMI是冠心病最常见的表现形式,动态心电图能及早检出SMI的存在,因而具有其独特的应用价值。     

312例老年患者无症状心肌缺血的动态心电图分析

目的：探讨24 h动态心电图（Holter）对老年患者无症状心肌缺血（SM I）的临床价值。方法：回顾分析我院门诊及住院312例老年患者的Holter资料。结果：Holter检出有236例检出ST段压低,其中单纯无症状性心肌缺血发作192例,有症状心肌缺血44例。SM I发生率明显高于有症状心肌缺血（P〈0.05）,发生于凌晨6-12 h频率最高。结论：Holter可早期发现老年人的无症状心肌缺血,这有助于对老年冠心病的病情评估和早期防治。     

动态心电图在隐匿型冠心病中的诊断价值

动态心电图（AECG）指连续记录24h或更长时间的心电图，该项检查首先由美国学者Holter于20世纪60年代初用于临床，故又称Holter监测，已成为临床上广泛使用的无创性心血管病诊断手段之一。无症状性心肌缺血（SMI）亦称隐匿型冠心病，是冠心病（CHD）的一种临床类型，由于患者心肌缺血发作时不伴有心绞痛症状，因此不易被普通心电图检出。现就Hoher对隐匿型冠心病的诊断价值作如下讨论。     

12导联动态心电图在老年无痛性心肌缺血诊断中的应用

目的:探讨12导联动态心电图(Holter)对老年冠心病无症状性心肌缺血(SMI)早期发现的临床意义。方法:对450例老年冠心病患者进行Holterr检测,同时记录常规标准12导联心电图,对两种检测结果进行比较。结果:Holter对心肌缺血的检出率是标准12导联心电图检出率的5倍,Holter对无症状性心肌缺血的检出率是有症状性心肌缺血检出率的5.5倍,二者比较有统计学意义(P<0.05)。无症状性心肌缺血发生有昼夜规律。结论:以Holter具有的优势,目前成为冠心病患者早期发现SMI的重要手段之一,使老年冠心病患者及时得到临床早期干预。     

动态心电图检测老年冠心病无症状心肌缺血的探讨

目的:探讨动态心电图(DCG)对监测心肌缺血,特别是老年无症状心肌缺血(SMI)的价值。方法:分析我院280例老年冠心病患者(有症状与无症状心肌缺血组)的DCG和临床资料。结果:静态心电图检出心肌缺血85例(30.5%),DCG检出心肌缺血180例(64.4%);SMI检出率为67.8%,有症状心肌缺血检出率为29.9%;两组患者在心肌缺血发作持续时间及ST段下降幅度方面差异无显著性;心肌缺血的发作及发作时伴发心律失常有明显的时间分布规律,均以6:00~12:00时为多见,以0:00~6:00时最为少见;无症状组恶性心律失常发生率明显高于有症状组。结论:DCG对SMI检出率高,有助于对老年冠心病的病情评估和早期防治。     

冠心病无痛性心肌缺血Holter的临床分析

目的：探讨冠心病患者无痛性心肌缺血和心律失常与Hoher的相关性。方法：应用Holter监测96例冠心病患者心肌缺血发生阵次。每次缺血发作时间和ST段最大压低，以及昼夜缺血次数。结果：无病性心肌缺血（SMI）70例，占74％，伴典型心肌绞痛8例，占8％；昼夜发作规律为6：00—12：00发生最高，检出632阵次占57．5％。结论：Holter对心肌缺血和心律失常就其种类、时间、数量与日常活动的关系，变化规律以及药物的疗效进行详细的观察，是监测心肌缺血和心律失常有效方法之一。     

动态心电图对于无症状心肌缺血的诊断价值研究

目的探讨动态心电图在诊断无症状性心肌缺血（SMI）的临床价值。方法对2011年7月-2012年12月在该院诊治的98例冠心病患者实施24h动态心电图检查。主要记录ST段压低阵数及心绞痛情况。结果98例冠心病患者中,24h动态心电图检出心肌缺血87例（88．78％）,其中13例（14．94％）为有症状的心肌缺血,74侧（85．06％）为无症状的心肌缺血。无症状心肌缺血的发作高峰时间段是上午的6～12点间,最低为O～6点间,2个时段的sMI发生率差异有统计学意义（P〈0．05）。有缺血型的ST段压低为240阵次,有症状的心肌缺血47阵次占19．33％,SMI的193阵次占80．67％。经统计学比较,有症状与无症状的心肌缺血在ST段压低变化的比较,差异有统计学意义（P〈0．05）。sT段降低幅度是1～3mm,SMI发作时心率较快,差异有统计学意义（P〈0．05）。结论无症状心肌缺血是冠心病患者比例大,实施24h动态心电图检测,可有效检出无症状的心肌缺血病例。且能够明确发病时间段,为临床诊治提供了有效依据。     

350例冠心病患者24h动态心电图分析

目的 对350例冠心病患者24h动态心电图监测的结果进行分析探讨，从而评价12导联动态心电图对冠心病的诊断价值。方法 使用ECG／ABHOLTER12TOP版检测仪，通过24h心电监测，观察冠心病患者24h动态心电图检出的心律失常、心肌缺血、心率变异性（HRV）的有关资料。结果 检出心肌缺血248例，其中无症状心肌缺血（SMI）189例．141例不伴有心绞痛发作。检出心律失常661例次，冠心病患者常见的心律失常依次为室上性早搏、室性早搏、房性心动过速。350例患者中检出102例HRV降低（29％），其中无症状心肌缺血69例（67％）。结论 无症状心肌缺血可作为不稳定型心绞痛发作的一项重要预后指标，冠心病人特别是SMI与HRV有一定关系。     

189例冠心病患者动态心电图诊断分析

目的：探讨24小时动态心电图对冠心病无症状性心肌缺血（SMI）的诊断价值及临床意义。方法：选择了我院2007年3月至2009年8月住院并行动态心电图检查的患者324例进行研究,按患者年龄分为三组进行分析比较。结果：检出有心肌缺血者189例占58．3％,有症状心肌缺血84例占27．36％,无症状心肌缺血105例占32．4％;61岁以上年龄组中无症状心肌缺血发生率、无症状心肌缺血出现的阵次及心律失常发生率均高于其他两组（P〈0．05）。结论：无症状心肌缺血是冠心病患者最常见的表现形式之一。动态心电图是检测无症状性心肌缺血的重要方法,对病情的判断和诊断具有重要的临床意义。     

12导动态心电图检测冠心病无症状性心肌缺血临床分析

无症状性心肌缺血（SMI）是指有客观证据的心肌缺血，而不伴随有各种类型心绞痛症状。随着12导动态心电图（Holter）的出现，先症状性心肌缺血的检出率明显增加，这对于冠心病的诊治有着突破性的进展。本文是笔者近3年来，通过12导动态心电图检测270例冠心病患者的临床情况，记录到无症状性心肌缺血182例，对其发作情况及规律进行了分析探讨，现报告如下。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

Luo Lingjie's Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.