情绪调节量表的信度和效度研究

目的 考察情绪调节量表的信度和效度.方法 采用新近编制的情绪调节量表对5个样本共1163名大学生被试进行了测试.结果 情绪调节量表具有良好的信度指标,重新评价和表达抑制维度的重测信度系数分别是0.85和0.87;5个样本和总样本两个维度的α系数和G系数均达到了0.76以上.验证性因素分析的结果显示两因子相关为自由估计的标准测量模型与实际数据的拟合程度良好(χ2为364.21,χ2/DF为4.79,NFI为0.96,NNFI为0.96,IFI为0.97,CFI为0.97,RMSEA为0.057),两因子相关为0的独立模型与标准测量模型之间无显著差异.效标效度的研究显示5个样本和总样本两个维度的效标指数均达到了0.70以上.实证效度的研究发现男性被试在表达抑制维度上的得分要显著高于女性被试.结论 情绪调节量表具有良好的心理测量学品质,值得进一步推广和应用.     

青少年执行功能量表的编制

目的 编制适用于考察青少年执行功能状况的量表.方法 根据执行功能的定义和结构成分,确定包含37个条目的初始量表,以分层抽样的方式选取来自全国2个省的1 722名青少年进行施测,分析量表的内部一致性信度、结构效度和效标效度.结果 编制成的青少年执行功能量表共21个条目,包含抑制控制、认知灵活性、工作记忆等3个维度,共解释方差的45.39％,因子载荷范围在0.499～0.727之间;量表及各因子的Cronbach＇sα系数在0.786～0.897之间;因子结构与实际数据相契合,其拟合指数分别为x2=530.44、df=186、RESMA=0.053、GFI=0.93、AGFI=0.91、NFI=0.96、CFI=0.97.结论 量表信效度良好,适合于评估我国青少年执行功能状况.     

SF-12v2量表评价社区居家养老模式下老年人健康状况的信度和效度分析

目的　探讨应用健康调查12条简表第2版（SF-12v2量表）评价社区居家养老模式下老年人健康状况的信度和效度。方法　2017年7—11月采用两阶段抽样法抽取广州市451名社区居家养老的老年人为研究对象,应用SF-12v2量表对其健康状况进行调查,同时采用欧洲五维健康量表5个维度（EQ-5D-5L）的定序数据作为效标。SF-12v2量表信度分析采用Cronbach's α系数和Spearman-Brown分半信度系数,效度分析采用内容效度（集合效度与区分效度）、结构效度和效标效度。结果　信度方面,SF-12v2量表总的Cronbach's α系数为0.876,两个分半量表的Spearman-Brown分半信度为0.873。效度方面,8个维度的集合效度和区分效度均为100.0%,因子分析提取公因子共2个,累计解释65.94%的总变异,SF-12v2生理健康子量表总分与EQ-5D-5L量表行动能力、自我照顾、日常活动、疼痛/不舒服维度中度相关（r值分别为0.591、0.436、0.606、0.590,P<0.01）,SF-12v2心理健康子量表总分与EQ-5D-5L量表焦虑/沮丧维度中度相关（r=0.517,P<0.01）。结论　SF-12v2量表应用于社区居家养老模式下老年人健康状况评价时,具有较好的信度和效度,能够客观反映老年人的健康状况。     

D型人格量表在儿童少年情绪障碍患者中的信度效度研究

目的 评价D型人格量表中文版的信度和效度.方法 将D型人格量表译成中文,并回译.205例情绪障碍儿童和少年,正常儿童和少年组156名完成D型人格量表,EPQ人格问卷测评.结果 D型人格量表中文版内部一致性α系数0.88,重测信度0.76,分半信度系数为0.82;探索性因素分析证实了两个主要因子:消极情感和社会抑制(特征值大于1,累计贡献率为53.65%);负荷量≥0.4的共有13个条目,结构效度、效标效度和实证效度好.总量表与艾森克E、N分量表相关系数分别为-0.55和0.56,相关具有显著性(P＜0.01).结论 该量表中文版经初步测试,信度、效度符合要求,可用于儿童和少年情绪障碍的人格测查.     

D型人格量表在儿童少年情绪障碍患者中的信度效度研究

目的评价D型人格量表中文版的信度和效度。方法将D型人格量表译成中文，并回译。205例情绪障碍儿童和少年，正常儿童和少年组156名完成D型人格量表，EPQ人格问卷测评。结果D型人格量表中文版内部一致性α系数0．88，重测信度0．76，分半信度系数为0．82；探索性因素分析证实了两个主要因子：消极情感和社会抑制（特征值大于1，累计贡献率为53．65％）；负荷量≥0．4的共有13个条目，结构效度、效标效度和实证效度好。总量表与艾森克E、N分量表相关系数分别为-0．55和0．56，相关具有显著性（P〈0．01）。结论该量表中文版经初步测试，信度、效度符合要求，可用于儿童和少年情绪障碍的人格测查。     

中文版基本心理需要满足量表的修订

目的 修订中文版基本心理需要满足量表(BNSG-S),并检验其信效度.方法 采用分层取样的方法对全国5个单位的6366名青年职工进行问卷调查,回收有效问卷6071份.通过项目分析筛选项目,对数据进行探索性因素分析和验证性因素分析检验问卷的结构效度,用幸福感指数量表来检验效标效度,并检验问卷的信度.结果 经过3次探索性因素分析,最后得到的中文版BNSG-S有15个条目,包含4个因子,分别为:自主需要满足、自主需要满足受阻、归属需要满足、归属需要满足受阻,累计方差贡献率为63.95％.验证性因素分析所得指标均符合心理测量学的要求(RMSEA=0.056,NFI=0.97,NNFI=0.96,CFI =0.97).中文版BNSG-S总分与幸福感指数量表的相关系数为0.50(P＜0.01),各维度与幸福感指数量表也显著相关.中文版BNSG-S的Cronbachα系数为0.76,其中,各因子的Cronbach α系数分别为0.80,0.67,0.83,0.80.结论 基本心理需要满足量表中文版具有较好的信效度,包括四个因子,可作为测量中国人基本心理需要满足的工具.     

精神分裂症患者自我管理量表的信效度分析

目的 对自行发展的精神分裂症患者自我管理量表进行信效度测试.方法 采用方便取样,选择北京市8所社区卫生服务中心的396名精神分裂症患者进行内部一致性检验、重测信度、探索性因子分析、验证性因子分析、校标关联效度的测试.结果 精神分裂症患者自我管理量表总量表Cronbach＇s α系数为0.96,总量表重测信度为0.791.通过探索性因子分析提取了6个因子,累计方差贡献率为61.70％,验证性因子分析结果证实样本拟合的模型较好（CFI：0.95,NFI：0.93,RMSEA：0.10）,进一步支持精神分裂症患者自我管理6因子结构模型;效标关联效度测试结果显示精神分裂症患者自我管理量表总分与慢性病自我管理自评量表（PIH）总分之间存在中等相关（r=-0.653,P=0.000）.另外精神分裂症患者自我管理量表的总分基本能够区分不同文化程度、居住状况、有无工作以及经济负担患者的自我管理的差异.结论 新发展并测试的精神分裂症患者自我管理量表具有较好的信度、效度以及可行性.     

已婚男性性商量表的编制与信效度检验

目的 编制测量已婚男性性商量表,检验其信度和效度.方法 用已婚男性性商量表测量全国9个省(市)22～70 岁已婚男性520人,回收有效问卷477人,效标样本192人,间隔2周重测样本32人.通过因子分析等考察量表的信度与效度.结果 新编量表条目与总分相关在0.450到0.723之间,各条目决断值(CR)均有显著性;重测信度为0.981,Cronbach'sα系数为0.940,分半信度为0.905;通过探索性因子分析提取5个公因子,解释方差总变异的55.90%,因子载荷在0.420～0.755之间.新编量表总分以及五个分量表(性生理、性心理、性爱抚、性欲、性交流)与效标Olson婚姻质量问卷(ENRICH)三个分量表和国际勃起功能指数-5(IIEF-5)有一定的正相关,相关系数在0.249～0.710之间.结论 已婚男性性商量表具有较好的信度和效度,可以用于我国男性性健康水平的评估.     

青少年情绪调节能力量表的编制

目的 编制适合中国青少年的情绪调节能力量表.方法 在文献综述和实证分析相结合的基础上,以703名青少年为被试进行施测,通过项目分析、探索性因素分析和验证性因素分析形成最终量表.结果 量表包括情绪控制力、情绪恢复力和策略应用力3个因子,量表的内部一致性信度为0.874,重测信度为0.851,验证性因素分析表明3因子具有良好的拟合指数(x2/df=3.06,NNFI=0.95,CFI=0.96,RMSEA=0.079).结论 青少年情绪调节能力量表具有良好的心理测量学特性.     

简化乌德勒支应对方式量表中文版在大学生中的试用

目的:评估简化乌德勒支应对方式量表中文版本(UCL-14)的信效度及其在大学生中的使用.方法:用UCL-19进行预测,经过探索性因子分析删减修改量表为UCL-14,再用UCL-14对480名大学生进行检测,1月后从原样本中随机抽取145个样本重测,用认知情绪调节问卷(CERQ)、社交性应激反应问卷(RSQ-SSV)为效标,评估与抑郁症状的相关性.结果:最终中文版简化UCL-14总量表Cronbach a系数为0.78,各分量表的a系数在0.63 ～ 0.77之间;总量表重测信度0.84,分量表的重测信度在0.71～0.82之间;验证性因子分析显示数据拟合良好,具有较好的结构效度.结论:简化乌德勒支应对方式量表中文版具有较好的信效度,可以用于大学生的应对方式测量.     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

Development on Adjustable Calibration Marker for Shock Wave Focus

Shock wave lithotripsy （SWL） is a treatment of choice for upper urinary stones. However, this procedure is inappropriate for obese patients because the focus is often unable to reach the target owing to the limited focal distance in shock wave source. Although treating such patients in a blast path may increase the application length of shock wave source, it＇s difficult to find this path on the lithotripter monitor. For this reason, we invented an adjustable calibration marker in order to set an effective focus in the shock wave hath.     

Study on the TCM Pathogenesis of Angiopathic Complications of Type II Diabetes

Excess production of reactive oxygen species(ROS)of mitochondrion mediated by hyperglycemia is the common pathogenesis of angiopathic complications of diabetes.TCM holds that the damp from the dysfunction of spleen.kidney and liver is the causative factor of complications of diabetes.This is similar to the mechanism of Ros resulting in angiopathic complications of diabetes.When the angiopathic complications of type II diabetes mellitus(T2DM)are difierentiated as caused by turbid damp in TCM can be explained as ROS.Since the obstruction of pathogenic damp in channels and collaterals is said to be the main pathogenesis,the treating principle should be dissolving the damp to remove the obstruction.     

Leptin, Ghrelin and TNF-α before and after Hypo-caloric Traditional Chinese Diet and Auricular Acupuncture

INTRODUCTION Obesity is a complex emergent problem, which can be possibly solved not only by the diet but also by the life style and promotion of a constant physical exercise. 1, 2 No doubt careful attentions must be given to the nutritional condition of obese people, the dietary habits, the somatic build (i.e. distribution of fat mass) and the organic functions linked to formation of the fat mass. All the parameters should be constantly monitored before, during and after a diet treatment. 3, 4, 5     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

Relationship between Dysglycemia and Carotid Atherosclerosis in Tibetan Population

People with dysglycemia are at high risk for atherosclerotic diseases. This study aims at investigating the atherosclerotic vascular damage in dysglycemia and its metabolic origin in Tibetan population.     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

CLINICAL SIGNIFICANCE OF SERUM CYTOKINES IL-1β,sIL-2R,IL-6,TNF-α,AND IFN-v IN ACUTE CORONARY SYNDROME

Objectives To explore serum cytokines levels (including IL-1 β, sIL-2R, IL-6, TNF-α, and IFN-v) and their significance in patients with acute coronary syndrome (ACS) and the subsequent follow-ups, with attempt to estimate the role of various serum inflammatory markers in the diagnosis and assessment of ACS.Methods The study population include 40 patients with acute myocardial infarction (AMI), 40 patients with unstable angina pectoris (UAP), and 40 controls. Among the 80 patients, 60 patients attended a follow up 4 months later. Serum inflammatory markers including IL-1 β, sIL-2R, IL-6, TNF-α, and IFN-v were measured by enzyme linked immunosorbent assay.Results Serum IL- 1 β, sIL-2R, IL-6, TNF-α were significantly higher in AMI group or UAP group compared to the control group and became significantly lower 4 months later in the follow-up patients. Serum levels of IFN-v shows no significant difference between AMI group or UAP group and controls, also showing no significant change when measured in follow up patients. There was no correlation between serum creatine kinase-MB isoenzyme levels and serum inflammatory markers either in UAP or AMI group. Furthermore, when divided into two subgroups using Wagner's QRS scoring system in the AMI group, there is no difference of each serum inflammatory marker between ≤ 6 scores group and ＞ 6 scores group.Conclusion Serum levels of certain inflammatory markers may have some diagnostic value for ACS, and can be a useful marker reflecting disease stability.     

Possible Spread of adenovirus type 3 from poultry to humans ：indirect evidence from an outbreak in China

Objective:To explore the epidemiology and etiology for an outbreak of acute respiratory tract infection that occurred in one county of Jiangsu Province, China 2004. Methods: Only cases meeting the case definition were included in the study. We reviewed the medical records of the cases who were admitted to the local hospitals, interviewed cases by a standard questionnaire, and then described the epidemiotogic features and analyzed risk factors by means of a case-control study. We collected pharyngeal swab specimens and sent them to different laboratories for isolation and culture. The laboratory used different detection methods such as DIP, PCR, electron microscope examination and microneutralization assay, to identify and then type the positive specimens. Results:A total of 871 cases were reported during the period from April 18 to July 4,2004. The distribution of onset times presented two peaks, one in late May and another in middle June. The epidemic occurred mainly in the elementary and junior high schools in ten townships of one county, and the mean age of the cases was 12 years (range 7 months to 18 years). The course of the disease was acute, and was characterized by fever accompanied with sore throat and tonsillitis. The WBC count of cases was normal or elevated. The mean duration of illness was 5 days (range 2 to 12 days). No fatalities from illness were reported. A case-control study indicated that the possible risk factors were close contact with a case and/or poultry before onset and sharing of towels among members of the family. The typical CPE was observed through inoculating pharyngeal swab specimens into the HEP-2 cell cultures in different laboratories. An infection of adenovirus type 3 was verified by detecting positive specimens in different methods. Conclusion:This investigation demonstrated that the acute respiratory infection in cases was caused by adenovirus type 3. Cases occurred in over 70 schools in ten townships in 2004, and the route of transmission was possibly close contact with cases or droplet transmission.