赣榆县胃癌影响因素1：1配对病例对照研究

目的 探讨赣榆县胃癌危险因素及保护因素,为该地区胃癌防治工作提供依据.方法 对319例新发胃癌病例及其1:1配对的健康对照者进行相关因素调查,应用条件Logistic回归对相关因素进行分析.结果 胃癌的主要危险因素为进食热烫食物(OR=2.21,95CI:1.57～3.12)、上消化道炎症患病史(OR=4.26,95%CI:2.59～7.03)、癌症家族史(OR=2.29,95%CI:1.37～3.82);主要保护因素为经常生吃大蒜(OR:0.64,9CI:0.42～0.96)、经常饮茶(OR=0.37,95%CI:0.25～0.54).结论 胃癌的发病与不良的膳食习惯、上消化道炎症及癌症家族史有关,生吃大蒜和饮茶能有效预防胃癌的发生.     

大肠癌与饮食相关危险因素病例对照研究

目的 探讨与大肠癌发病相关的饮食危险因素,为大肠癌的防治提供科学依据.方法 采用配对病例对照研究的方法,选择2007-2008年辽宁省大连市新发大肠癌患者200例及同期住院符合配对条件的对照200例,使用统一设计的调查表进行问卷调查;应用SPSS13.0软件中的COX回归模型进行单因素和多因素条件Logistic回归分析.结果 多因素分析结果显示,10年前较多食用腌制食品(OR=2.154,95%CI=1.554～2.986)、动物肝脏(OR=6.553,95%CI=1.810～23.721)、煎、炸、烤制食品(OR=2.689,95%CI=1.387～5.214)是大肠癌相关饮食危险因素,而10年前较多食用新鲜蔬菜(OR=0.505,95%CI=0.310～0.821)、鸡肉(OR=0.490,95%CI=0.273～0.879)及生蒜(OR=0.467,95%CI=0.278～0.783)是大肠癌的保护因素;单因素分析结果表明,2组10年前在摄人贝类、豆类及其制品的食用频次方面差异有统计学意义.结论 大连市大肠癌的发病主要与10年前较少摄入新鲜蔬菜、生蒜、鸡肉及过多摄入腌制食品、动物肝脏、煎、炸、烤制食品等因素密切相关.     

北京市门头沟区成人膳食模式与高血压患病及防治的关系

目的了解北京市门头沟区居民膳食模式的特点,探讨膳食模式与高血压患病及防治的关系。方法通过多阶段整群随机抽样,选取北京市门头沟区成人居民为调查对象。因子分析建立膳食模式,因子得分的大小,由低到高三分位划分为T1 (低分位)、T2 (中分位)、T3 (高分位),并应用多分类Logistic回归分析膳食模式与高血压患病及防治的关系。结果北京市门头沟区常住居民存在3种主要的膳食模式,健康膳食模式、西化膳食模式和传统膳食模式。Logistic回归结果显示,以每种膳食模式的T1为参照,健康膳食模式是高血压新检出的(T2:OR=0.775;T3:OR=0.726)、高血压现患未控制(T3:OR=0.717)的保护因素,西化膳食模式与高血压现患控制(T3:OR=0.696)呈负关联,传统膳食模式是高血压新检出(T3:OR=1.431)的危险因素。结论健康膳食模式是高血压新发、高血压现患未控制的保护因素,西化膳食模式与高血压现患控制负相关,传统膳食模式是高血压新发的危险因素。提倡科学合理膳食、健康的饮食习惯对于预防和控制高血压具有重要意义。     

石家庄市正定县青少年近视与营养相关的影响因素研究

目的 探究影响青少年近视患病情况的营养相关因素,为实现近视的一级预防提供参考依据。方法 2021年10月采用分层抽样的方法,抽取正定县青少年385人进行视力检测,体格检查及问卷调查(一般情况及膳食调查)。运用单因素分析及lasso回归筛选变量,Logistic回归探究近视可能的影响因素。因子分析对饮食模式进行提取,分析其与近视的关联性。结果 385名青少年近视患病率为68.6%。多因素分析发现进食油炸食品(OR=8.480, 95%CI:1.058～67.971)为近视的危险因素;摄入奶及奶制品(OR=0.994, 95%CI:0.991～0.999)、大豆及坚果(OR=0.997, 95%CI:0.994～0.999),父母双方均不近视(OR=0.312, 95%CI:0.115～0.845),每周4节体育课(OR=0.269, 95%CI:0.074～0.984)为近视的保护因素(P<0.05)。因子分析共提取出3种饮食模式,分别是多样化、大豆杂粮及零食饮料饮食模式。Logistic分析发现大豆杂粮饮食模式对近视具有保护作用(OR=0.85, 95%CI:0.73～0.99,...     

徐州地区膳食模式与乳腺癌的相关性研究

目的探讨膳食模式与乳腺癌发病风险的关系,为乳腺癌的防治提供营养膳食指导。方法采用病例对照研究,对徐州地区2所三级医院225例经病理或影像学确诊的新发乳腺癌患者及225例健康体检妇女进行问卷调查。采用半定量食物频率调查表进行膳食调查,利用SPSS16.0主成分分析法探索所有研究对象的膳食模式,采用多因素Logistic回归模型分析膳食模式与乳腺癌发病风险的关系。结果共得到8种膳食模式,分别为杂豆膳食模式、油盐膳食模式、动物内脏膳食模式、肉制品膳食模式、水果膳食模式、鱼肉膳食模式、米面膳食模式、奶制品膳食模式。校正混杂因素后发现杂豆膳食模式(OR:0.210,95%CI:0.112～0.395;OR:0.286,95%CI:0.157～0.522;OR:0.392,95%CI:0.214～0.719)、奶制品膳食模式(OR:0.549,95%CI:0.310～0.971)为乳腺癌的保护因素;油盐膳食模式为乳腺癌的危险因素(OR:2.258,95%CI:1.266～4.028;OR:2.081,95%CI:1.176～3.684),差异具有统计学意义(P0.05)。结论杂豆膳食模式、奶制品膳食模式为乳腺癌的保护因素,油盐膳食模式为乳腺癌的危险因素,可通过合理的膳食指导预防乳腺癌的发生。     

赣榆县食管癌流行影响因素病例对照研究

目的探讨赣榆县食管癌有关危险因素及保护因素。方法对新发食管癌病例及其健康对照者开展相关因素调查,应用非条件Logistic回归对相关危险和保护因素进行分析。结果食管癌的主要危险因素为住地有污染（OR=1.94）,进食快（OR=1.67）、咸（OR=1.47）、热烫（OR=2.33）、不按时（OR=1.20）,常喝生水（OR=1.12）,无遮盖存粮（OR=1.40）、粮食霉变（OR=1.56）,经常吸烟（OR=1.86）、吸烟部位深（OR=1.70）、家庭成员吸烟（OR=1.48）、工作场所被动吸烟（OR=1.74）,经常饮酒（OR=1.31）,性格抑郁（OR=1.82）,癌症家族史（OR=2.14）;主要保护因素为常吃胡椒粉（OR=0.83）、经常生吃大蒜（OR=0.86）、粮食存放一段时间食用（OR=0.96）。结论食管癌的发病主要与不良的膳食习惯及吸烟饮酒等因素有关,性格、家族史、住地污染及粮食霉变等因素也不容忽视。在人群中倡导常吃胡椒粉、生吃大蒜及做好粮食的适当存放,有利于推动食管癌的群防群控。     

高寒地区老年人群膳食模式与慢性病的相关性分析

目的了解高寒地区老年人群的膳食模式类型并分析不同膳食模式与慢性病的相关性。方法采用多阶段分层整群随机抽样方法抽取齐齐哈尔市年龄≥65周岁的2 738名常住居民进行调查,运用因子分析的方法建立膳食模式,应用logistic回归模型分析不同膳食模式与慢性病的关系。结果经因子分析提取出4种膳食模式:模式1"动植物蛋白膳食模式"、模式2"零食小吃膳食模式"、模式3"果蔬类膳食模式"、模式4"谷薯类膳食模式";经logistic回归分析显示,模式1是肥胖的危险因素(OR=1.309,95%CI=1.027～1.669,P0.05);模式2是糖尿病的危险因素(OR=1.319,95%CI=1.040～1.672,P0.05);模式3是高脂血症的保护因素(OR=0.722,95%CI=0.541～0.964,P0.05)。结论动植物蛋白膳食模式及零食小吃膳食模式能够增加高寒地区老年人慢性病的发病风险;应针对不同膳食模式人群加强公众健康教育,倡导平衡膳食,控制慢性病的发生发展。     

莲都区居民膳食减盐预防高血压知信行调查

目的了解丽水市莲都区居民膳食减盐预防高血压知识、态度和行为水平,为开展居民膳食减盐预防高血压干预提供依据。方法采用多阶段整群随机抽样方法,抽取丽水市莲都区2个街道和3个乡镇18～69岁常住居民开展问卷调查和测量血压,分析莲都区居民高血压患病情况和膳食减盐预防高血压知识、态度、行为水平及其影响因素。结果共纳入1 801人,完成调查1 509人,应答率为83.79%。检出高血压481例,高血压患病率为31.88%。居民膳食减盐预防高血压知识知晓率为33.40%,态度持有率为60.70%,行为持有率为58.58%。Logistic回归分析结果显示,女性(OR=1.583,95%CI:1.248～2.008)、高血压(OR=1.734,95%CI:1.303～2.308)、30～40岁(OR=0.368,95%CI:0.226～0.597)、初中及以上文化程度(OR=0.057～0.403,95%CI:0.036～0.577)是膳食减盐预防高血压知识水平的影响因素;女性(OR=1.342,95%CI:1.072～1.679)、已婚(OR=1.582,95%CI:1.167～2.144)、初中及高中文化程度(OR=0.235～0.525,95%CI:0.163～0.736)、膳食减盐预防高血压知识(OR=2.640,95%CI:2.033～3.430)是膳食减盐预防高血压态度的影响因素;女性(OR=1.632,95%CI:1.304～2.044)、30～40岁(OR=0.494,95%CI:0.346～0.705)、农村(OR=1.617,95%CI:1.276～2.050)、慢性病家族史(OR=1.455,95%CI:1.148～1.845)、膳食减盐预防高血压知识(OR=1.396,95%CI:1.084～1.797)、膳食减盐预防高血压态度(OR=4.059,95%CI:3.203～5.145)是膳食减盐预防高血压行为的影响因素。结论莲都区居民膳食减盐预防高血压知识知晓率、态度和行为持有率较低,提高居民知识和态度水平,可促进膳食减盐预防高血压行为。     

舟山市定海区流动孕妇膳食营养的知行信调查

目的了解舟山市定海区流动孕妇膳食营养的知识、态度、行为（知信行）状况及影响因素,为制定针对性的健康教育提供参考。方法选取在定海区盐仓街道社区卫生服务中心定期产检的436例流动孕妇作为研究对象。采用面对面问卷调查的方法进行膳食营养知信行调查,分析本地区流动孕妇膳食营养的知信行状况及影响因素。结果定海区流动孕妇的膳食营养总得分为（29.5±3.5）分,总体不及格人数201人,占46.1%。膳食营养态度及格人数比例为72.9%,膳食营养行为56.9%,膳食营养知识为66.5%。经多因素非条件logistic回归分析,年龄（OR=1.004,95%CI=1.000-3.827）、接受过相关宣教（OR=2.391,95%CI=1.217-6.843）、低文化水平（OR=1.105,95%CI=1.014-5.826）和低经济收入水平（OR=1.071,95%CI=1.002-4.742）为影响流动孕妇膳食营养知信行得分的主要影响因素。结论定海区流动孕妇膳食营养的知识水平及饮食习惯有待提高,应对低文化、低收入、低年龄段的流动孕妇针加强对性的膳食营养宣教。     

大学新生膳食模式及其影响因素的研究

目的 了解大学新生的膳食模式,分析其膳食模式的影响因素。方法采取分层整群随机抽样的方法,调查1319名大学新生的膳食模式及其影响因素。结果发现4种膳食模式：Ⅰ（摄入较多的汉堡包及油炸食品、腌制食品、坚果类、零食、可乐、雪碧、咖啡、糖类）、Ⅱ（摄入较多的猪肉、羊肉、牛肉、禽肉、动物肝脏、鱼虾类、海带/海鱼/紫菜等海制品、坚果类）、Ⅲ（摄入较多新鲜水果、鸡蛋、鱼虾类、海带/海鱼/紫菜等海制品、奶及奶制品、豆类及豆制品、坚果类）、Ⅳ（摄入较多的粮谷类、新鲜蔬菜、新鲜水果、猪肉）。多因素logistic回归分析显示,主要影响其膳食模式的因素：(1)男生膳食模式Ⅰ、Ⅱ与居住地点(OR= 1.67,95％CI:0.87～3.19;OR=1.51,95％CI:0.79～ 2.88)、就餐地点（OR= 1.63,95％CI:1.03～2.59;OR= 1.83,95％CI:1.04～ 3.23）、母亲的文化程度（OR=2.52,95％CI:1.07 ～ 5.95;OR=3.38,95％CI:1.50 ～ 7.63）、家庭经济状况（OR=2.24,95％CI：1.30 ～ 3.88;OR=3.06,95％CI:1.77～ 5.29）、被动吸烟(OR= 1.80,95％CI:0.70 ～ 4.59;OR=1.83,95％CI:0.75 ～4.45)呈正相关。膳食模式Ⅲ与母亲的文化程度呈负相关（OR=0.56,95％CI:0.17～ 1.79）;膳食模式Ⅳ和就餐地点呈正相关(OR=1.83,95％CI:1.04 ～ 3.23),但是与母亲的文化程度呈负相关( OR=0.56,95％CI:0.17～ 1.79)。(2)女生与男生相比,膳食模式Ⅰ和居住地点、就餐地点关系不大;而对于膳食模式Ⅱ、Ⅲ来说,被动吸烟对女生影响也不大。结论大学新生的膳食模式受社会人口统计学及生活方式等多种因素影响。     

Dietary fat and fatty acids and risk of colorectal cancer in women

The authors examined the association of intakes of different types of fat and fatty acids with risk of colorectal cancer using data from the Women's Health Study, a randomized trial of low-dose aspirin and vitamin E carried out among 39,876 healthy US women aged >/=45 years. Among the 37,547 women eligible for the present study, 202 developed colorectal cancer during an average follow-up period of 8.7 years (1993-2003). Intakes of dietary fat and its food sources were assessed at baseline by food frequency questionnaire. Cox proportional hazards regression was used to estimate relative risks and 95% confidence intervals. Total fat intake was not related to colorectal cancer risk, nor were intakes of the different types of fat and major fatty acids. However, the authors observed a positive association between intake of fried foods away from home and colorectal cancer risk (highest quintile vs. lowest: relative risk = 1.86, 95% confidence interval: 1.09, 3.16; p for trend = 0.01). These prospective cohort data provide little support for an association between dietary fat and colorectal cancer risk. However, intake of fried foods and/or other factors related to their intake may be associated with colorectal cancer development. This finding warrants further examination.     

Comparisons of food intake between breast cancer patients and controls in Korean women

The purpose of this study was to compare food intakes between Korean breast cancer patients and a healthy control group. We compared the intake of nutrients of 117 food items between Korean breast cancer patients (n=97) and age matched healthy controls (n=97). Nutrient intake was estimated using a quantitative food frequency questionnaire. The mean caloric intake of breast cancer patients and healthy controls was not significantly different. Breast cancer patients consumed significantly less fat and antioxidant nutrients such as vitamin A, retinol, β-carotene, vitamin C and vitamin E when compared to the control subjects. Among the food items, the intake of eggs (p<0.01), legumes (p<0.05), vegetables (p<0.05), seasonings (p<0.001), and oils and fats (p<0.01) in breast cancer patients was significantly lower than that in the controls. These results suggest that Korean breast cancer patients consumed less amount of soy and vegetables, which are rich source of antioxidant nutrients and phytosterols. Thus, dietary guidance to increase intake of these foods may be beneficial in the prevention of breast cancer.     

Dietary fibre and risk of colorectal cancer in the Breast Cancer Detection Demonstration Project (BCDDP) follow-up cohort

BACKGROUND: The hypothesis that increased intake of dietary fibre lowers the risk of colorectal cancer (CRC) has recently been weakened by results from cohort and intervention studies that did not detect such an association. We investigated the association between dietary fibre intake and risk of CRC in a cohort of women that prospectively answered a food frequency questionnaire (FFQ). METHODS: We studied 45 491 women in the Breast Cancer Detection Demonstration Project (BCDDP) follow-up cohort. A 62-item FFQ was administered from 1987 and 1989 to assess dietary intake. Participants received follow-up questionnaires (in 1992-1995 and 1995-1998) on which they reported incident cancers. Cases were also identified through searches of the National Death Index and state cancer registries. Cox proportional hazard regression was used to generate risk ratios and 95% CI for quintiles of total fibre intake and fibre subtypes. RESULTS: During a mean follow-up time of 8.5 years we identified 487 colorectal cancer cases. The 10th and 90th percentiles of dietary fibre intake were 5.4 g and 18.2 g respectively. For total fibre we observed no association with colorectal cancer (fifth versus first quintile, RR = 0.94, 95% CI: 0.71-1.23). Analyses by subgroup of fibre and by anatomical subsite did not reveal any stronger inverse associations. CONCLUSIONS: Within a cohort of older women characterized by a relatively low fibre intake, there was little evidence that dietary fibre intake lowers the risk of colorectal cancer.     

Dietary calcium and vitamin D intake and risk of colorectal cancer: a prospective cohort study in women

Although laboratory data and a few adenoma prevention trials suggest that calcium supplementation may reduce the risk of colorectal neoplasia, the results of observational studies of calcium intake and colorectal cancer risk are contradictory. However, few studies have examined the association among women or effects in specific colon subsites. Women with colorectal cancer diagnosed through 31 December 2000 were identified by linkage to regional cancer registries. During an average 11.3 yr of follow-up of 61,463 women, we observed 572 incident cases of colorectal cancer. Using data obtained from a 67-item food frequency questionnaire and Cox proportional hazards models to estimate rate ratios and 95% confidence intervals, we found an inverse association between dietary calcium intake and colorectal cancer risk. Women with the highest calcium intake (median 914 mg/day) had a reduced risk of colorectal cancer (rate ratio = 0.72, 95% confidence interval = 0.056-0.93, P for trend = 0.02) compared with women with the lowest intake (median 486 mg/day). Furthermore, our results suggest that the inverse association may be strongest in relation to distal cancers and among older women. The association with dairy products was less clear, suggesting that calcium intake per se is more important than specific calcium sources. Vitamin D intake was not clearly associated with risk. In sum, our data suggest that high calcium intake may lower colorectal cancer risk.     

Dietary fiber and whole-grain consumption in relation to colorectal cancer in the NIH-AARP Diet and Health Study

BACKGROUND: Whether the intake of dietary fiber can protect against colorectal cancer is a long-standing question of considerable public health import, but the epidemiologic evidence has been inconsistent. OBJECTIVE: The objective was to investigate the relation between dietary fiber and whole-grain food intakes and invasive colorectal cancer in the prospective National Institutes of Health-AARP Diet and Health Study. DESIGN: The analytic cohort consisted of 291 988 men and 197 623 women aged 50-71 y. Diet was assessed with a self-administered food-frequency questionnaire at baseline in 1995-1996; 2974 incident colorectal cancer cases were identified during 5 y of follow-up. The Cox proportional hazards model was used to estimate the relative risks (RRs) and 95% CIs. RESULTS: Total dietary fiber intake was not associated with colorectal cancer. The multivariate RR for the highest compared with the lowest intake quintile (RR(Q5-Q1)) was 0.99 (95% CI: 0.85, 1.15; P for trend = 0.96). In analyses of fiber from different food sources, only fiber from grains was associated with a lower risk of colorectal cancer (multivariate RR(Q5-Q1): 0.86; 95% CI: 0.76, 0.98; P for trend = 0.01). Whole-grain intake was inversely associated with colorectal cancer risk: the multivariate RR(Q5-Q1) was 0.79 (95% CI: 0.70, 0.89) for the whole cohort (P for trend < 0.001). The association with whole grain was stronger for rectal than for colon cancer. CONCLUSIONS: In this large prospective cohort study, total dietary fiber intake was not associated with colorectal cancer risk, whereas whole-grain consumption was associated with a modest reduced risk.     

Association of dietary quercetin with reduced risk of proximal colon cancer

Quercetin is a flavonol that appears to be protective against several cancers, but its possible role in prevention of colorectal cancer is not yet well studied. We evaluated dietary intakes of quercetin and risk of colorectal cancer in a large case-control study conducted in metropolitan Detroit, Michigan (N = 2664). The protective effects of quercetin intake, as assessed by a food frequency questionnaire, were confined to risk of proximal colon cancer. Stratified analyses showed that the protective effects of quercetin on risk of proximal colon cancer were significant only when fruit intake or the Healthy Eating Index score was high, or when tea intake was low, with odds ratios (OR) for the highest vs. the lowest quartile of 0.49, 0.44, and 0.51, respectively. Increased quercetin intake had no protective effects when tea intake was high. Interestingly, increased intake of quercetin was associated with increased risk of distal colon cancer when total fruit intake was low (OR for the highest vs. the lowest quartile = 1.99). These results suggest that quercetin can have disparate effects on colon cancer risk depending on whether dietary intakes of fruit or tea are high, and that quercetin had protective effects only on proximal, not distal, colon cancer.     

Intakes of calcium and vitamin D and risk of colorectal cancer in women

In vivo and in vitro studies have suggested a protective role of calcium and vitamin D in the development of colorectal cancer. However, epidemiologic data have been inconclusive. The authors prospectively assessed intakes of calcium and vitamin D in relation to risk of colorectal cancer in a large, prospective, female cohort from the US Women's Health Study. In 1993, 39,876 women aged > or = 45 years and free of cardiovascular disease and cancer were enrolled in the study. During an average follow-up of 10 years, 223 of 36,976 women eligible for the present study developed colorectal cancer. Intakes of calcium and vitamin D from dietary sources and supplements were assessed with a baseline food frequency questionnaire. Cox proportional hazards regression was used to estimate relative risks and 95% confidence intervals. Intakes of total calcium and vitamin D were not associated with risk of colorectal cancer; multivariate relative risks comparing the highest with the lowest quintile were 1.20 (95% confidence interval: 0.79, 1.85; p for trend = 0.21) for total calcium and 1.34 (95% confidence interval: 0.84, 2.13; p for trend = 0.08) for total vitamin D. Intakes of both nutrients from specific types of sources, including diet and supplements, were also not significantly associated with colorectal cancer risk. Data provide little support for an association of calcium and vitamin D intake with colorectal cancer risk.     

大肠癌相关因素的条件logistic回归分析

目的 探讨与大肠癌发病相关的危险因素,为大肠癌的防治提供科学依据.方法 采用1:1配对病例对照研究方法,对大连市新发200例大肠癌患者及相同数量的对照使用统一设计的调查表进行调查.所获资料根据资料的类型采用χ~2检验、秩和检验或单因素条件logistic回归分析进行单因素分析,然后对初步筛选出的与大肠癌发病关系密切的研究因素,纳入多因素条件logistic回归模型进行多因素分析.结果 多因素条件logistic回归分析结果 显示,便秘史、其他癌症家族史、十年前较多食用腌制食品以及平常爱生闷气为大肠癌的相关危险因素,而十年前较多食用新鲜蔬菜为大肠癌的相关保护因素.单因素分析结果 还显示,居住地周围有排污工厂、熬夜史、腹部放射线检查史、大肠癌家族史、痔疮史、阑尾炎及阑尾手术史、十年前较多食用贝类、煎、炸、烤制食品、动物肝脏、经常感到有压力、不愿和别人沟通、处事态度偏于悲观及与同事相处一般等为大肠癌的危险因素.同时,十年前较多摄入鸡肉、豆及其制品、生蒜、体育锻炼及其频次、十年前人均月收入及生活费用高为大肠癌的保护因素.结论 大连市大肠癌的发病是多因素综合作用的结果 ;便秘史、其他癌症家族史、经常爱生闷气、十年前较少摄入新鲜蔬菜及过多摄入腌制食品等因素与大肠癌的发生的关系值得关注.     

Lifestyle and colorectal cancer: A case-control study

A case-control study has been conducted to investigate the relationship between lifestyle and risk of colorectal cancer. Cases are one hundred patients diagnosed with colon and rectal cancer in Tokai University Hospital between 1986 and 1994. Three controls per case were individually matched by age, sex, local areas and date of health checkups at the Automated Multi-phasic Health Testing and Services (AMHTS ) Center of the hospital. The results were analyzed by multi-factorial logistic regression models. Positive history of maternal cancer, large consumption of alcohol, frequent consumption of potato products and white-collar job were predominant risk factors while frequent intake of seaweed was a protective factor. Frequent intakes of dairy foods and lack of exercise showed no significant tendency to increase risk of colorectal cancer. Smoking habits, intakes of meat and egg were shown not to be related to this disease. These findings suggest that family history of cancer and dietary factors play a key role in causation and prevention of colorectal cancer.     

萧山区大肠癌发病危险因素的病例对照研究

目的：探讨萧山区人群大肠癌发生的危险因素。方法：采用以医院和社区为基础的1∶2病例对照研究方法,对102例经过病理学确诊的大肠癌患者及204例对照的相关资料进行条件Logistic回归分析。结果：大肠癌的危险因素有红肉和腌制食物（腌肉、咸鱼）食用频率,情绪自我调节能力差,下消化道疾病史,肿瘤家族史。其OR值及95%CI分别为4.99（2.14-11.65）、3.71（1.27-10.88）、2.60（1.03-6.56）、4.66（1.65-13.16）、3.30（1.43-7.62）;保护因素有白肉、新鲜水产类、新鲜蔬菜类食用频率,体育锻炼,OR值分别为0.09（0.03-2.22）,0.30（0.14-0.66）,0.21（0.09-0.49）,0.16（0.03-0.80）。结论：大肠癌的发生与饮食因素、性格特征、下消化道疾病和肿瘤家族史密切相关。