单侧外固定支架治疗股骨不愈合

股骨干骨折造成骨不愈合,临床上时有发生,且治疗上各有不同的方法。本人从1993年以来收治12例股骨干骨折不愈合病例,均采用单侧外固定支架加植骨治疗,取得较为满意效果。临床资料12例股骨不愈合骨折均由外伤所致的中1/3段骨折。均符合骨折不愈合的诊断标准。伤期最短为13个月零4天,最长为26个月。男8例,女4例。年龄最大者51岁,最小者9岁。按X线分型:肥大型3例,萎缩型5例,骨缺损4例,12例均有不同程度的皮肤瘢痕粘连,肌肉萎缩和膝关节僵直,12例中除2例未做切开内固定外,10例均做过不同类型的切开内固定术,其中有4例做过二次以上手术。治疗方…     

单侧多功能外固定支架治疗胫骨骨不连

自1990年12月～1996年11月,采用于仲嘉研制的单侧多功能外固定支架治疗不同因素引起的胫骨陈旧性骨折骨不连共26例。均达到一期临床愈合,报告如下。临床资料本组26例均符合骨不连的诊断标准。男21例,女5例,年龄18～57岁,平均40.2岁。病史最短者为骨折后3个月,最长者60个月。平均9个月。均为外伤性胫腓骨骨折。其中粉碎性骨折9例;开放伤19例,闭合伤7例;伴软组织缺损10例;伴骨缺损及局部皮肤窦道7例;伴感染11例。伤肢关节废用性僵直,其中膝关节3例,踝关节5例,膝、踝关节均存在2例;形成胫骨假关节2例;外院或本院行内固定治疗21例,行石膏托固定…     

单侧外固定架治疗四肢骨折术后骨不愈合

我院从 1995年 2月至 1997年 8月 ,采用单侧多功能外固定架加自体骨植骨术治疗四肢骨折内固定术后不愈合 33例 ,疗效较好 ,报告如下。1　临床资料骨折不愈合的诊断标准[1] 为 :骨折术后 6个月 ,临床检查有异常活动或假关节 ,Ｘ线检查无骨折愈合征象。本组随访31例 ,均为单侧肢体 ,男 2 8例 ,女 3例 ;年龄 2 1～ 6 2岁 ,平均35 5岁 ;胫骨 17例 ,肱骨 7例 ,股骨 5例 ,尺桡骨各 1例 ;其中16例骨折端伴有不同程度的骨缺损 ,17例伴有不同程度的关节活动受限。不愈合时间为 6～ 42个月 ,平均 13 2个月。2　手术方法上肢采用臂丛麻醉 ,下肢采用连…     

胫腓骨中下段骨折切开复位单侧外固定器治疗的体会

报告1994至1996年5月应用切开复位+Batiani型单边式外固定支架治疗胫腓骨中下段骨折34例,平均随诊1年6个月。无骨不愈合及固定失败,该支架对软组织创伤小,且固定可靠,能防止骨感染发生并有利于早期功能锻炼。     

单侧外固定支架治疗胫腓骨中下1/3骨折不愈合39例体会

<正> 我院骨科从1997年3月～2002年2月共收治胫腓骨中下1/3骨折39例,采用手术切除硬化骨折端,钻通髓腔,植骨并单侧多功能外固定支架(简称支架)加压固定治疗,经随访15年,疗效满意,现报告如下。 1 临床资料 1.1 一般资料:本组39例,男24例,女15例;年龄在17～68岁,平均41岁;左28例,右11例;经手法复位单纯夹板或     

单侧外固定架治疗四肢骨折的相关问题探讨

我们自 1992年 9月～ 1995年 12月 ,运用多功能单侧外固定架治疗四肢骨折 97例 ,10 6个肢体 ,现就有关问题进行探讨。1　临床资料本组 97例中男 6 9例 ,女 2 8例 ;年龄 13～ 49岁。双侧肱骨骨折 2例 ,同侧或对侧股骨合并胫腓骨骨折 4例 ;肱骨合并股骨骨折 1例 ,合并胫腓骨骨折 2例 ;骨不连 5例 (肱骨 2例 ,胫骨 2例 ,1例软组织缺损 ,钢板外露后取出钢板 ) ;股骨 1例 ;股骨颈骨折 4例 ;股骨骨折 7例 (其中多段骨折 2例 ) ;肱骨骨折 9例 ;胫腓骨骨折 6 3例 (其中合并大的血管神经损伤2例 )。 97例中 10 6肢体开放损伤 46例 ,开放损伤均在伤后1…     

小腿骨折的单侧多功能外固定支架治疗

目的 探讨临床应用单侧多功能外固定支架治疗小腿骨折的手术方法、适应证、优缺点、主要合并症的防治及术后护理。方法 自1996～2004年对39例复杂、开放性小腿骨折、邻近关节的小腿骨折、小腿骨折内固定术后合并感染行单侧多功能外固定支架治疗。结果 所有病例均达到骨性愈合。平均愈合时间为4个月，去除外固定支架时间为6个月。结论 外固定支架治疗小腿骨折具有独特的优越性。     

单侧骨外固定器治疗四肢长干骨骨折及并发症

单侧骨外固定器治疗四肢长干骨骨折具有很多优点,临床应用日益增多。自1997年至2005年6月,我们采用单侧多功能外固定器治疗四肢长干骨骨折293例,收到满意的效果,但也出现了一些并发症。回顾分析其产生原因,并提出防治措施如下。1临床资料1.1一般资料:本组293例,其中男168例,女125例;年龄8~93岁,平均32岁。肱骨干骨折56例,股骨干骨折10例,股骨髁间骨折12例,胫腓骨干骨折215例(开放性骨折96例,闭合性骨折119例;横断骨折36例,斜形或螺旋形骨折95例,粉碎性骨折84例)。陈旧性骨折6例(胫腓骨干骨折2例,肱骨干骨折3例,股骨髁间骨折1例,均为二次手术…     

单侧多功能外固定架的临床应用体会

我院自 1995年 9月～ 2 0 0 1年 5月应用单侧多功能外固定支架治疗骨科临床多类疾病 63例 ,取得满意治疗效果 ,总结如下。临床资料一、一般资料　本组 63例 ,男 42例 ,女 2 1例 ,年龄 11～84岁 ,平均 3 4岁。应用于开放性胫腓骨骨折 3 0例 ,股骨干骨折骨不连 12例 ,股骨转子间骨折 8例 ,肱骨干骨折 5例 ,膝关节融合术 6例 ,肱骨骨囊肿 2例。二、治疗结果　随访 0 .5～ 4年 ,平均愈合时间 :胫腓骨14 w,股骨 2 0 w,粗隆间 12 w,肱骨干 8w,膝关节融合 (未植骨 ) 10 w,肱骨骨囊肿腓骨移植 10 w。 63例均接近解剖复位 ,邻近关节活动良好。三、并…     

胸腰椎骨折椎弓根内固定断裂与植骨融合方式的相关性分析

[目的]探讨胸腰椎骨折椎弓根螺钉内固定系统内固定术后,椎弓根螺钉断裂与植骨融合方式之间的关系,以探讨胸腰椎骨折植骨融合的最佳方式。[方法]回顾性研究1995年5月~2005年12月本院脊柱外科收治的胸腰椎骨折病人197例,其中A组单纯内固定(不植骨)患者14例,B组“H”形椎板植骨21例,C组横突间植骨67例,D组椎间、椎内联合横突间植骨95例。[结果]术后随访6~32个月,内固定断裂12例,其中A组4例,B组3例,C组5例,D组0例,4组中D组内固定断裂率显著低于其他3组(P<0.05)。[结论]椎间、椎体内联合横突间植骨重建脊柱三柱的稳定性,符合人体生物力学原理,能有效降低内固定断裂的发生。     

On the measurement of the functional properties of the CFTR

A number of methods are currently employed to assess the functional properties of CFTR channels and their response to pharmacological potentiators, correction of the defective CFTR trafficking, and vectorial introduction of new proteins. Here we review the most common methods used to assess CFTR channel function. The suitability of each technique to various experimental conditions is discussed.     

The Measurement of the Inclination Angle of the Hamate and Analysis of the Inclination Angle for the Rotation Deformity of the Little Finger in the Fixation of the Carpometacarpal Joint

ObjectiveComplex base fractures of the fifth metacarpal bone and dislocation of the fifth carpometacarpal joint are more prone to internal rotation deformity of the little finger sequence after fixation with a transarticular plate. In the past, we have neglected that there is actually a certain angle of external rotation in the hamate surface of transarticular fixation. This study measured the inclination angle of the hamate surface relative to the fifth metacarpal surface for clinical reference.MethodsIn a prospective single‐center study, we investigated the tilt angle of 60 normal hamates. The study included thin‐layer computed tomography (CT) data from 60 patients from the orthopaedic clinic and inpatient unit from January 2017 to March 2020, including 34 men and 26 women who were 15~59 years old, average 35 years old. The CT data of 60 cases in Dicom format of the hand was input into Mimics and 3‐Matics software for three‐dimensional (3D) reconstruction and measuring the angle α between hamate surface and the fifth metacarpal surface. According to the possible placement of the transarticular plate on the fifth metacarpal surface, we measured the angle β between the hamate surface 1 and the fifth metacarpal surface and the angle γ between the hamate surface 2 and the fifth metacarpal surface.ResultsThe average angle between the hamate surface and the fifth metacarpal surface was 11.66°. The hamate surfaces 1 and 2 have an external rotation angle of 7.30° and 7.51° on average with respect to the fifth metacarpal surface, respectively. There is no statistically significant difference in the angles between the two groups (P > 0.05).ConclusionsThe horizontal angle of the dorsal side of the hamate is different from the back of the fifth metacarpal surface, and the hamate has a certain external rotation angle with respect to the fifth metacarpal surface. No matter how the transarticular plate is placed, the plate always has a certain external rotation angle relative to the fifth metacarpal surface. When the fixation is across the fifth carpometacarpal joint, if the plate does not twist and shape, it will inevitably cause internal rotation of the fifth metacarpal, resulting in internal rotation deformity of the little finger sequence.     

静脉输注甘露醇开放血脑屏障对抗生素透过血脑屏障的影响

目的　通过快速静脉输注甘露醇可逆性开放血脑屏障 (BBB) ,探知此方法能否增加抗生素透过BBB的量 ,在何时达到最高峰 ,其通透量增加后临床上有无不良反应。方法　采用自身配伍设计 ,共 6个样本组。对照组仅使用抗生素 ;其余 5组分别在使用甘露醇前 60、3 0min ,同时使用甘露醇后 3 0、60min使用抗生素 ,各组皆取使用抗生素后 1h的脑脊液测其抗生素浓度。抗生素选用头孢三嗪。结果　测量值经过q检验 ,经 2 0 %甘露醇处理前后的CSF中的头孢三嗪浓度差异有非常显著性。全组患者经临床观察未出现神经系统的不良反应。结论　经静脉快速输注2 0 %甘露醇后可以使透过BBB的水溶性抗生素的量增加 ,两者使用的顺序是在抗生素使用 3 0min内即给予甘露醇快速滴注。该方法不会增加低神经毒性抗生素在中枢神经系统的不良反应。     

三角韧带损伤的手术治疗

[目的]探讨踝关节三角韧带损伤的手术治疗及效果。[方法]2002年4月-2005年4月治疗伴有三角韧带损伤的踝关节骨折40例，均采用切开复位和坚强内固定，并修复重建三角韧带，恢复踝关节内外侧结构的稳定性。下胫腓联合分离仍不稳定者，给予皮质骨螺钉横向内固定。[结果]全部病例得到16个月-3a随访，平均1．5a。按齐氏疗效评定标准：优良30例，可8例，差2例，优良率75％。[结论]强调踝关节骨折切开解剖复位，坚强内固定的同时，应充分重视修复重建三角韧带。     

Influence of the design of the prosthesis on the outcome after hemiarthroplasty of the shoulder in displaced fractures of the head of the humerus

We reviewed 39 patients with displaced three- and four-part fractures of the humerus. In 21 patients (group A) we had used an anatomical prosthesis for the humeral head and in 18 (group B) an implant designed for fractures. When followed up at a mean of 29.3 months after surgery the overall Constant score was 51.9 points; in group A it was 51.5 and in group B 52.4 points. The subjective satisfaction of the patients was assessed using a numerical rating scale and was similar in both groups. In group A complete healing of the tuberosities was found in 29% and 50% in group B. Partial integration was seen in 29% of group A and in only one patient in group B, while resorption was noted in 43% of group A and 44% of group B. The functional outcome was significantly better in patients with complete or partial healing of the tuberosities (p=0.022). The specific trauma prosthesis did not lead to better healing of the tuberosities. The difference in clinical outcome obtained by the two designs did not reach statistical significance.     

Preservation of the pylorus and resection of the head of the pancreas

The historical evolution of the pylorus-preservation resection of the head of the pancreas is traced from the first resections early in this century to relative standardization of the operation, to a lowering of the operative mortality, and to an interest in improving nutritional status after resection. There are many theoretical advantages for the function of the upper gastrointestinal tract after pylorus and gastric preservation, such as maintenance of gastric capacitance and equilibration of osmotic pressure in gastric digestants, foodstuff digestion and absorption, and bowel motility. After the pylorus-preserving resection, gastric emptying is normal, pyloric function to prevent duodenal reflux is often normal, and gastric acids and serum levels of duodenal hormones are at normal levels, whereas after standard pancreatoduodenectomy, all of these are often abnormal. No prospective blinded studies have been published comparing nutritional values after the two operative procedures, but evidence is presented of a satisfactory result with regard to gastric capacitance, body weight gain, and lack of postgastrectomy symptoms. An undoubted advantage of the pylorus-preserving feature is a simplification of the operation. These gains are achieved without increase in operative mortality, without increase in the incidence of jejunal ulcer, and without theoretical or actual decrease in value of the procedure as a cancer operation, except in patients with duodenal carcinoma proximal to the ampulla of Vater.