Risk of Developing Fibroadenoma with the Use of Cyclosporine A in Renal Transplant Recipients |
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| Authors: | Figen Binokay Mustafa Balal Erkan Demir Saime Paydas Sureyya Soyupak Yasar Sertdemir |
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| Affiliation: | 1. Department of Radiology, Faculty of Medicine, Cukurova University, Balcali Adana, Turkeyfbinokay@cu.edu.tr;3. Department of Nephrology, Faculty of Medicine, Cukurova University, Balcali Adana, Turkey;4. Department of Urology, Faculty of Medicine, Cukurova University, Balcali Adana, Turkey;5. Department of Radiology, Faculty of Medicine, Cukurova University, Balcali Adana, Turkey;6. Department of Biostatistics, Faculty of Medicine, Cukurova University, Balcali Adana, Turkey |
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| Abstract: | To investigate the effect of cyclosporine A (Cyc A) on the development of fibroadenomas, 30 renal transplant patients and 20 chronic renal failure patients on dialysis were breast examined with ultrasonography and/or mammography. Of the renal transplant patients, 17 were receiving Cyc A-based combination therapy for immunosuppression. All patients were female with the age range of 29.7 ± 9.2 years in the transplant group and 33.95 ± 9.91 in the dialysis group. Eight of the 17 patients receiving Cyc A had fibroadenomas, 5 of them having bilateral lesions. None of the other patients, those on dialysis and on non-Cyc A combination therapy had fibroadenomas. A significant difference for fibroadenoma incidence in patients receiving Cyc A combination immunosuppression was found. |
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| Keywords: | cyclosporine A (Cyc A) fibroadenoma renal transplantation chronic renal failure (CRF) ultrasonography |
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