急性冠脉综合征患者焦虑抑郁情绪的随访

目的观察急性冠脉综合征（acute coronary syndrome，ACS）患者焦虑抑郁情绪的变化。方法对782例ACS患者的焦虑抑郁情绪进行平均（8．0±5．8）m的随访测评，应用综合性医院情绪测量表（hospit alanxiety and depressionscales，HADS）、贝克焦虑量表（Beck Anxiety Inventory，BAI）和贝克抑郁量表（Beck Depression Inventory，BDI），分析ACS患者焦虑抑郁情绪的变化。结果与基线期相比，ACS患者的抑郁评分下降具有统计学意义[（7．07±5．37）vs（6．28±5．51），P〈0．05]，焦虑评分下降无统计学意义（P〉0．05），焦虑、抑郁的构成比例无统计学意义（P〉0．05o结论ACS后抑郁程度虽然呈现自然下降趋势，但构成比例降低却无统计学意义，故仍需早发现，早治愈。关于ACS后的焦虑有待进一步深入研究。

Follow-up of anxiety and depression symptoms in patients with acute coronary syndrome

Objective To observe changes in anxiety and depression symptoms in acute coronary syndrome patients. Methods A prospective cohort study of 782 patients with ACS were followed up anxiety and depression symptoms were as- sessed and collected, application of hospital anxiety and depression scales （HADS）, beck anxiety inventory （ BAI ） and beck depression inventory （BDI）. Results The follow-up Beck depression inventory （BDI） score decreased significantly compared with the baseline BDI score [（7.07 ±5.37 ） vs （ 6.28 ±5.51, P〈0.05]. Meanwhile scores of anxiety symptoms and proportion of anxiety and depression were found no any significant changes （P〉 0.05 ）. Conclusion Among ACS popu- lation, though the depression level was decline spontaneously 7 months later, the proportions of anxiety and depression were still as high as the baseline, So as for the improvement of clinic outcome of ACS population, post-ACS depression should be assessed and treated effectively as early as possible. In the case of post-ACS anxiety, large sample and long term investigations were needed to make it clear.