全文获取类型
收费全文 | 7161篇 |
免费 | 392篇 |
国内免费 | 26篇 |
专业分类
耳鼻咽喉 | 70篇 |
儿科学 | 389篇 |
妇产科学 | 120篇 |
基础医学 | 547篇 |
口腔科学 | 139篇 |
临床医学 | 485篇 |
内科学 | 1757篇 |
皮肤病学 | 97篇 |
神经病学 | 450篇 |
特种医学 | 193篇 |
外科学 | 1569篇 |
综合类 | 190篇 |
一般理论 | 2篇 |
预防医学 | 260篇 |
眼科学 | 247篇 |
药学 | 404篇 |
中国医学 | 35篇 |
肿瘤学 | 625篇 |
出版年
2023年 | 81篇 |
2022年 | 150篇 |
2021年 | 271篇 |
2020年 | 155篇 |
2019年 | 217篇 |
2018年 | 257篇 |
2017年 | 162篇 |
2016年 | 234篇 |
2015年 | 195篇 |
2014年 | 317篇 |
2013年 | 399篇 |
2012年 | 595篇 |
2011年 | 558篇 |
2010年 | 366篇 |
2009年 | 275篇 |
2008年 | 440篇 |
2007年 | 469篇 |
2006年 | 352篇 |
2005年 | 353篇 |
2004年 | 322篇 |
2003年 | 254篇 |
2002年 | 207篇 |
2001年 | 117篇 |
2000年 | 93篇 |
1999年 | 85篇 |
1998年 | 57篇 |
1997年 | 53篇 |
1996年 | 50篇 |
1995年 | 37篇 |
1994年 | 25篇 |
1993年 | 18篇 |
1992年 | 39篇 |
1991年 | 40篇 |
1990年 | 30篇 |
1989年 | 38篇 |
1988年 | 31篇 |
1987年 | 19篇 |
1986年 | 18篇 |
1985年 | 27篇 |
1984年 | 19篇 |
1983年 | 16篇 |
1982年 | 9篇 |
1981年 | 9篇 |
1980年 | 15篇 |
1979年 | 9篇 |
1978年 | 9篇 |
1976年 | 9篇 |
1974年 | 15篇 |
1973年 | 7篇 |
1972年 | 10篇 |
排序方式: 共有7579条查询结果,搜索用时 15 毫秒
71.
72.
Vikas A. Gupta Shannon M. Matulis Benjamin G. Barwick R. Devin Bog Conrad W. Shebelut Mala Shanmugam Paola Neri Nizar J. Bahlis Madhav V. Dhodapkar Leonard T. Heffner Craig C. Hofmeister Nisha S. Joseph Sagar Lonial Jonathan L. Kaufman David L. Jaye Ajay K. Nooka Lawrence H. Boise 《Blood cancer journal》2022,12(8)
73.
Anti-ulcerogenic effect of banana powder (Musa sapientum var. paradisiaca) and its effect on mucosal resistance 总被引:1,自引:0,他引:1
Orally administered banana pulp powder (Musa sapientum var. paradisiaca) was shown to have significant anti-ulcerogenic activity in rats subjected to aspirin, indomethacin, phenylbutazone, prednisolone and cysteamine and in guinea-pigs subjected to histamine. Banana powder not only increased mucosal thickness but also significantly increased [3H]thymidine incorporation into mucosal DNA. Relative to untreated control sections, histological studies showed that banana treatment increased staining by alcian blue in the apical cells with staining noted in the deeper layers of the mucosal glands. Banana-treated and control sections were also stained for DNA by the Feulgen reaction. The banana-treated sections showed a greater aggregation and intensity of pink spots when compared to controls. The present study suggests that banana powder treatment not only strengthens mucosal resistance against ulcerogens but also promotes healing by inducing cellular proliferation. 相似文献
74.
Bhakti Gajjar Sanjay Sharma Erum Khan Pranita Sharma Pawan Jain Vikas Goel Arvind Neral Jyotish Patel Mamta Parmar Kanika Sharma Vijay K. Sharma Arvind K. Sharma 《Medicine》2022,101(27)
India has the second highest number of cases of sickle cell disease (SCD) and affects the most socioeconomically disadvantaged communities living in a horizontal belt from Gujarat to Odisha state. Despite high prevalence, information about cerebral hemodynamics among children with SCD in India remains scarcely described.We performed transcranial Doppler (TCD) to assess cerebral hemodynamics among Indian children with SCD and evaluated their association with clinical and hematological parameters.Children aged 3-18years, diagnosed with SCD living in Raipur in Chhattisgarh and Ahmedabad in Gujarat state were recruited. TCD was performed to obtain flow velocities from middle cerebral (MCA), intracranial internal carotid (ICA) and basilar artery. Associations were evaluated between timed-average-mean-maximum velocities (TAMMV) and various clinical and hematological parameters.Our prospective study included 62 consecutive children with known SCD. Mean ± SD age of the study population was 9.8 ± 3.9 years and 31 (50%) were male. Mean ± SD hemoglobin was 8.64 ± 1.34 Gm/dL while the mean HbSS ± SD was 70.25 ± 15.27%. While 6 (9.6%) children had suffered from stroke during previous 2 years, 7 (11%) demonstrated abnormal TAMMV. Higher HbSS level along with history of iron chelation therapy, blood transfusion and/or stroke showed a trend towards having higher TAMMV.Stroke and cerebral hemodynamic alterations are common among Indian children with SCD. Larger studies with detailed neuroimaging and genetic evaluations are needed for better understanding, characterization, risk stratification as well as optimization of the timing of blood transfusion to reduce physical disabilities among Indian children with SCD. 相似文献
75.
76.
77.
Alessio Alfieri Juraj Koudelka Mosi Li Sanny Scheffer Jessica Duncombe Andrea Caporali Rajesh N Kalaria Colin Smith Ajay M Shah Karen Horsburgh 《Journal of cerebral blood flow and metabolism》2022,42(7):1176
Chronic microvascular inflammation and oxidative stress are inter-related mechanisms underpinning white matter disease and vascular cognitive impairment (VCI). A proposed mediator is nicotinamide adenine dinucleotide phosphate (NADPH) oxidase 2 (Nox2), a major source of reactive oxygen species (ROS) in the brain. To assess the role of Nox2 in VCI, we studied a tractable model with white matter pathology and cognitive impairment induced by bilateral carotid artery stenosis (BCAS). Mice with genetic deletion of Nox2 (Nox2 KO) were compared to wild-type (WT) following BCAS. Sustained BCAS over 12 weeks in WT mice induced Nox2 expression, indices of microvascular inflammation and oxidative damage, along with white matter pathology culminating in a marked cognitive impairment, which were all protected by Nox2 genetic deletion. Neurovascular coupling was impaired in WT mice post-BCAS and restored in Nox2 KO mice. Increased vascular expression of chemoattractant mediators, cell-adhesion molecules and endothelial activation factors in WT mice post-BCAS were ameliorated by Nox2 deficiency. The clinical relevance was confirmed by increased vascular Nox2 and indices of microvascular inflammation in human post-mortem subjects with cerebral vascular disease. Our results support Nox2 activity as a critical determinant of VCI, whose targeting may be of therapeutic benefit in cerebral vascular disease. 相似文献
78.
79.
Mai Fujiwara Radhika Raheja Lucien P. Garo Amrendra K. Ajay Ryoko Kadowaki-Saga Sukrut H. Karandikar Galina Gabriely Rajesh Krishnan Vanessa Beynon Anu Paul Amee Patel Shrishti Saxena Dan Hu Brian C. Healy Tanuja Chitnis Roopali Gandhi Howard L. Weiner Gopal Murugaiyan 《The Journal of clinical investigation》2022,132(10)