疼痛性瘀斑综合征1例

患者男,40岁。左小腿灼痛2天,伴发热,自服伤风胶囊、螺旋霉素等药物未缓解,门诊以“过敏性紫癜”收住院。体检:系统检查未见异常。皮肤科情况:左小腿中、上段伸侧见22cm×12cm长方形紫红色皮下瘀斑,局部肿胀,压不退色,境界不清。左大腿根部有3cm×3cm类似皮损。实验室检查:血常规WBC8.9×109/L,Hb156g/L,PLT220×109/L,出血时间3min,凝血时间2min,尿常规正常。皮损处组织病理示表皮下有片状含铁血黄素沉着,血管周围有出血改变及轻度炎细胞浸润。束臂试验(-),取自身红细胞在上臂内侧做点状皮下注射,24h观察,出现直径大于1.5cm×1.5cm的瘀…     

疼痛挫伤综合征一例

疼痛挫伤综合征是一种罕见疾病,以自发性的疼痛性瘀斑为特征,好发于女性,发病前常伴有精神疾病,病因及发病机制尚未明确,精神因素可能起到关键作用。本文报道1例疼痛挫伤综合征伴产后抑郁患者,临床表现为四肢疼痛性瘀斑,且伴有一过性凝血因子异常。抗抑郁治疗1个月后,瘀斑逐渐消退,疼痛症状缓解,随访4年未复发。     

Wiskott-Aldrich综合征一例报告

本病又名湿疹一血小板减少性免疫缺陷病,为性联隐性遗传病,临床少见,现将我院所遇一例,报告如下.     

Rud综合征一例报告

Rud综合征又名侏儒一鱼鳞病样红皮病-智能缺陷(Dwarfism-Ichthyosiform Erythroderma-Mental Deficiency)是由于先天性神经外胚叶发育不良所致的一种少见的疾病.国内未见报道,近来我科门诊遇到一例,现报告如下.     

CRST综合征一例报告

Winterbauer^①于1964年首先描述,种由皮肤钙质沉着(Galcinosis)、雷诺氏现象(Raynaud's.phenomenon),指趾硬化(Sclerodactylia)和毛细血管扩张(telangiectasia)综合征,简称多CRST综合征,国内尚未见报告,作者见到1例,报告如下:病例报告:女、28岁,因面、颈、胸、背及四肢出现蜘蛛痣样红斑8年,近两年来加重而入院.     

Haber综合征一例报告

<正> Haber综合征又称酒渣鼻样综合征,为少见的遗传性皮肤病。患者女,30岁。面部鳞屑性红斑及预胸部疣状皮损18年。5岁始面部散发糠皮疹,12岁后颜面泛发潮红及丘疹鳞屑,每因日晒或高温刺激而加重,红肿渗液,灼痛刺痒。冬季皮损干燥紧缩感。不久颈右     

Ramsey-Hunt综合征一例报告

<正> 患者女49岁。左侧外耳道及耳廓剧烈疼痛,就诊于耳科。发病前一周有轻微感冒及低热史。幼时曾患耳疾,遗留耳呜。耳科检查:外耳道通畅,深段鼓膜充血,鼓膜前下     

CREST综合征一例报告

患者女,17岁,近4-5年每逢冬季遇冷时两手足皮肤青紫,疼痛;近2-3年两手指有些发硬,活动不灵,右手小指不能伸直,右手拇指根部和小指尖发生溃疡.     

Graham-Little综合征一例报告

Graham-Little综合征是一种罕见的皮肤病.本综合征能否为一独立的疾病,与瘢痕性秃发(Brocq假性秃发)、扁平苔藓有何关系,意见尚不一致.我们于1985年见到一例,报告如下.     

Maffucci综合征一例报告

Maffucci综合征临床上罕见,我科最近见到1例,并伴有右股骨骨折,其临床及X线表现均较典型,兹报告如下.     

Gardner-Diamond syndrome

This paper presents a 26-year-old woman with the characteristic features of Gardner-Diamond syndrome: recurrent painful bruises reproducible by intradermal injection of autologous red blood cells, and a "hysterical" personality pattern together with nonspecific multisystem complaints.     

Gardner-Diamond syndrome with multiple glomus tumors.

The case of a patient with two unusual dermatologic entities, multiple glomus tumors and the painful purpura of Gardner-Diamond syndrome, is reported. The diagnosis of multiple glomus tumors was confirmed by biopsy, and the Gardner-Diamond syndrome was confirmed by reproduction of the painful purpura with the intradermal injection of the patient's sonicated erythrocytes.     

Gardner-Diamond syndrome: a systematic review of treatment options for a rare psychodermatological disorder

Gardner-Diamond syndrome (GDS) is a rare psychodermatological condition characterized by the formation of spontaneous, painful skin lesions that develop into ecchymosis following episodes of severe physiological or psychological stress. The majority of GDS cases occur in young adult females, and although the etiology of this rare disorder is unknown, there appears to be a psychological component correlated with the coexistence of previous psychiatric diagnoses. Due to the rare nature of this disorder, there exist few guidelines for prompt clinical diagnosis and optimal treatment. Here, a systematic review was conducted to include 45 cases of patients with GDS to better understand clinical presentation as well as current treatment options. Ultimately, GDS is a diagnosis of exclusion after other coagulopathies and causes of purpura are ruled out. High clinical suspicion following laboratory and clinical exclusion of known physiological causes is necessary for diagnosis. Selective serotonin reuptake inhibitors (SSRIs) and corticosteroids are cost effective first line treatments for GDS with proven efficacy in symptomatic relief. GDS refractory to initial treatment may require regular psychotherapy and titrated SSRI dosages to achieve long-term success. This review of available case studies serves to comprehensively describe the clinical presentation and available treatment approaches to this rare psychodermatological disorder.     

Goltz氏综合征一例报告

患者女,20岁.生后即有躯干、四肢线条状、点状坑凹,并有2片皮肤糜烂,左眼上下眼脸粘连,右手3, 4指并指,右腿短,左腿长等异常现象,婴幼期双口角、左眼角泪阜部发生红色小颗粒,渐大到绿豆粒大,1970年在某医院诊为乳头状瘤病,手术切除.其后左眼红色颗粒渐长到黄豆大桑堪状,1982年2月来我院眼科门诊,手术切除.     

重叠综合征1例

临床资料患者,女,39岁。主因面部麻木1年余,四肢无力半年,皮肤变硬3个月,于2008年3月来我科就诊。患者1年前无明显诱因出现右上唇皮肤麻木,伴烧灼感,3天后发展至整个右侧面部,半月后左侧面部亦受累,多次在当地医院按"面神经麻痹、     

Kindler综合征

报告1例Kindler综合征.患者男,54 岁.全身反复发生水疱、色素异常伴皮肤萎缩、手足角化性斑块6 年.面部及手部皮损日晒后加重,无明显自觉症状.患者出生和幼年时,无类似皮损发生.