2940 nm 铒激光治疗凹陷性痤疮瘢痕的疗效与安全性观察

目的：观察2940 nm铒玻璃激光治疗痤疮凹陷性瘢痕的疗效与安全性。方法：选取25例诊断为凹陷性痤疮瘢痕的患者,使用2940 nm铒激光治疗,每4周1次,共3次。治疗前后拍照并使用EC-CA权重评分、VISIA皮肤图像分析仪评估疗效,使用CK皮肤检测仪评估皮肤屏障功能。结果：治疗结束后,所有病例均有改善,临床有效率为28％。痤疮凹陷性瘢痕ECCA权重评分明显下降,与治疗前比较,差异有统计学意义（P＜0.05）,毛孔、紫质显著减少（P＜0.05）;治疗后1周与治疗前相比,经皮水分丢失量、油脂增多（P＜0.05）,含水量减少（P＜0.05）,治疗前与治疗1月后相比,经皮水分丢失量、含水量、油脂无明显差异（P值均＞0.05）。结论：2940 nm铒激光治疗痤疮凹陷性瘢痕有效,术后1月后皮肤屏障功能恢复。     

2940nm铒激光治疗凹陷性痤疮瘢痕的疗效与安全性观察

目的:观察2 940 nm铒玻璃激光治疗痤疮凹陷性瘢痕的疗效与安全性。方法:选取25例诊断为凹陷性痤疮瘢痕的患者,使用2 940 nm铒激光治疗,每4周1次,共3次。治疗前后拍照并使用ECCA权重评分、VISIA皮肤图像分析仪评估疗效,使用CK皮肤检测仪评估皮肤屏障功能。结果:治疗结束后,所有病例均有改善,临床有效率为28%。痤疮凹陷性瘢痕ECCA权重评分明显下降,与治疗前比较,差异有统计学意义(P<0.05),毛孔、紫质显著减少(P<0.05);治疗后1周与治疗前相比,经皮水分丢失量、油脂增多(P<0.05),含水量减少(P<0.05),治疗前与治疗1月后相比,经皮水分丢失量、含水量、油脂无明显差异(P值均>0.05)。结论:2 940 nm铒激光治疗痤疮凹陷性瘢痕有效,术后1月后皮肤屏障功能恢复。     

Profile铒激光治疗痤疮瘢痕128例疗效评价

目的:评价Profile铒激光治疗痤疮瘢痕的疗效。方法:Profile铒激光治疗痤疮瘢痕128例,其中凹陷性瘢痕106例,增生性瘢痕22例。结果:Profile铒激光治疗痤疮瘢痕的总有效率为93%,凹陷性瘢痕总有效率93.3%,增生性瘢痕总有效率92.2%。术后出现暂时性色素沉着6例(4.7%),均于3个月内基本消退。结论:Profile铒激光治疗痤疮瘢痕疗效好(凹陷性瘢痕优于增生性瘢痕),副作用小。     

铒YAG激光辅以胶原蛋白贴治疗面部凹陷性痤疮瘢痕疗效观察

目的观察铒YAG激光辅以胶原蛋白贴敷料治疗面部凹陷性痤疮瘢痕的临床疗效。方法将78例患者随机分为铒YAG激光辅以胶原蛋白贴敷料治疗组和铒YAG激光辅以金霉素软膏对照组,治疗3个月后,分别比较疗效及色素沉着发生率。结果治疗组、对照组有效率均为100.00%,治疗组色素沉着发生率为4.2%,对照组为20.0%,两者差异有显著性意义(P<0.05)。结论铒YAG激光辅以胶原蛋白贴敷料治疗面部痤疮凹陷性瘢痕疗效明确,术后色素沉着少。     

强脉冲光联合点阵铒激光治疗痤疮后增生性瘢痕的效果观察

目的观察痤疮后增生性瘢痕患者应用强脉冲光联合点阵铒激光治疗后效果。方法随机将我院91例痤疮后增生性瘢痕患者分组,对照组45例给予强脉冲光治疗,观察组46例联合点阵铒激光治疗,对比治疗疗效。结果观察组VSS评分低于对照组,总有效率高于对照组(P <0.05)。结论强脉冲光联合点阵铒激光有效改善瘢痕色泽、血管分布、厚度及柔软度,治疗痤疮后增生性瘢痕效果显著。     

点阵CO2激光联合皮下分离术治疗痤疮凹陷性瘢痕的疗效观察

目的分析点阵CO_2激光联合皮下分离技术治疗痤疮凹陷性瘢痕的应用价值。方法选取2018年6月到2020年10月某医院收治的痤疮凹陷性瘢痕患者82例,随机分为研究组(n=41)和对照组(n=41),对照组予以点阵CO_2激光治疗,研究组予以点阵CO_2激光联合皮下分离治疗。对比两组术前、术后6个月临床痤疮瘢痕评估量表(ECCA)权重评分、瘢痕面积、色素沉着面积变化和凹陷边缘直径减少50%所用时间变化。结果术后6个月,研究组ECCA权重评分明显低于对照组;术后6个月,研究组瘢痕面积、色素沉着面积明显小于对照组;研究组凹陷边缘直径减少50%所用时间明显短于对照短,且上述差异均有统计学意义(P 0.05)。结论点阵CO_2激光联合皮下分离技术治疗痤疮凹陷性瘢痕可促进瘢痕恢复,减少瘢痕面积和色素沉着面积。     

CO2点阵激光联合果酸治疗痤疮后凹陷性瘢痕的疗效分析

目的 观察痤疮后凹陷性瘢痕患者合用CO2点阵激光技术与果酸治疗的临床价值.方法 选取2018年10月至2020年3月某医院收治的的痤疮后凹陷性瘢痕患者100例,并以随机数表模式进行设组研究,对照组50例仅接受CO2点阵激光技术治疗,观察组50例在对照组基础上配合果酸涂抹,对比两组的疗效与安全性.结果 观察组总有效率(9...     

点阵CO2激光治疗痤疮凹陷性瘢痕的临床疗效观察

目的:为点阵CO2激光治疗痤疮凹陷性瘢痕寻找更佳的参数设置及治疗操作方法.方法:选取42例痤疮凹陷性瘢痕患者,面部两侧随机分为实验组、对照组,实验组采用点阵CO2激光"局部加强模式+大面积平扫模式";对照组采用单纯"大面积平扫模式",治疗间隔时间为2个月,共治疗2次,治疗前及每次治疗后2个月予痤疮瘢痕权重评分(ECCA...     

铒激光在治疗面部痤疮萎缩性瘢痕中的应用

面部痤疮多发于青春期人群,是一种毛囊皮脂腺单位的慢性炎症性皮肤病,萎缩性瘢痕属于痤疮瘢痕中最常见的类型,给患者的身心健康带来不利影响,根据Dreno的ECCA权重评分表把萎缩性痤疮瘢痕分为3种：V形瘢痕即点状凹陷性瘢痕;U形瘢痕：直径2～4mm,边缘锐利;M形瘢痕：直径〉4mm,边缘多不规则。我科于2006年引进profile超级平台,利用其中铒激光微剥脱模块2940nm波长进行面部治疗痤疮萎缩性瘢痕疗效观察,现报道如下。     

痤疮后凹陷性瘢痕的光电治疗进展

痤疮后凹陷性瘢痕是寻常痤疮最常见的后遗症,发生率较高,严重影响患者的心理健康及生活质量。其治疗方法有皮肤磨削、化学剥脱、微针疗法、组织填充术、外科疗法等。近年来,激光、强脉冲光及射频疗法逐渐被用于痤疮后凹陷性瘢痕的治疗,并取得良好的疗效。     

CO_2点阵激光Deep与Superficial模式联合治疗萎缩性痤疮瘢痕的临床分析

目的:评价CO2点阵激光Deep与Superficial模式联合治疗萎缩性痤疮瘢痕的临床疗效和安全性。方法:对纳入的20例萎缩性痤疮瘢痕患者进行病例对照研究,每例患者治疗2个疗程,治疗后3个月进行疗效和安全性评价,对治疗前后萎缩性痤疮瘢痕严重程度评分,评估临床疗效和不良反应,同时统计患者主观评价。结果:所有患者瘢痕严重程度评分由治疗前(64.3±19.8)分下降至(39.8±14.3)分,改善百分比达(37.6±9.6)%,其中17例患者认为皮损明显或显著改善,无严重不良反应。结论:CO2点阵激光Deep与Superficial模式联合治疗萎缩性痤疮瘢痕,是一种安全有效的新型治疗方法。     

萎缩性痤疮瘢痕治疗进展

萎缩性痤疮瘢痕治疗方法较多,主要包括激光治疗、非激光治疗及联合治疗,其中以现代激光和射频等新技术的研究进展较多。该文就现有方法对萎缩性痤疮瘢痕的治疗进展进行综述。     

富血小板血浆联合CO2点阵激光治疗萎缩性痤疮瘢痕疗效和安全性Meta分析

目的：系统评价富血小板血浆联合CO₂点阵激光治疗面部萎缩性痤疮瘢痕的有效性及安全性。方法：检索从建库到2019年7月Cochrane Library、Embase、Medline、中国知网、万方数据库及维普数据库中富血小板血浆联合CO₂点阵激光治疗面部萎缩性痤疮瘢痕的随机对照试验,筛选符合要求的文献并根据Cochrane偏倚风险评估方法评价纳入文献质量, 采用Revman5.3软件进行Meta分析。结果：最终纳入5个RCTs和Meta分析,结果显示：①联合疗法的总有效率和治愈率均高于单用激光组（P=0.008,0.0002）;②联合疗法和单用激光组的红斑、水肿持续时间及疼痛评分无统计学差异（P=0.21,0.35,0.50）。结论：富血小板血浆联合CO₂点阵激光治疗萎缩性痤疮瘢痕的疗效优于单独使用CO₂点阵激光,不良反应无明显差异。     

黄金微针射频联合低能量超脉冲CO2点阵激光治疗面部痤疮凹陷性瘢痕的疗效观察

 目的 观察黄金微针射频联合低能量超脉冲CO2点阵激光治疗面部痤疮凹陷性瘢痕的疗效。方法选取2018年4月—2020年4月就诊于河南大学第一附属医院的74例凹陷性痤疮瘢痕患者为对象,随机分为2组,每组各37例。治疗组采用黄金微针射频联合低能量超脉冲CO2点阵激光治疗;对照组采用黄金微针射频治疗。比较2组治疗前后痤疮瘢痕权重评分（ECCA）、瘢痕改善程度IGA评估及术后不良反应。结果2组治疗后ECCA评分均明显降低,但治疗组评分降低更明显(Z=-2.65,P＜0.05);治疗组IGA评估有效率较对照组高。2组不良反应发生率无统计学差异。结论黄金微针射频联合低能量超脉冲CO2点阵激光能更好地改善痤疮后凹陷性瘢痕,两种方法联合能够起到协同作用且不增加治疗相关副作用。     

Clinical trial of a laser device called fractional photothermolysis system for acne scars

Ablative laser resurfacing is an effective treatment for acne scars. However, edema and prolonged erythema are common. Additionally, scarring and hyperpigmentation are often induced. A new concept of laser called fractional photothermolysis has been designed to create microscopic thermal wounds to achieve skin rejuvenation without significant side-effects. We treated 10 patients with acne scars using this laser system (Reliant Fraxel SR Laser). All the patients were successfully treated with minimal adverse effects. The fractional photothermolysis system represents an optional method for the treatment of acne scars.     

Atrophic acne scar treatment using triple combination therapy: Dot peeling,subcision and fractional laser

Abstract

Atrophic scars are a common complication of acne. Many modalities are proposed but each does not yield satisfactory clinical outcomes. Thus, a new combination therapy is suggested that incorporates (i) dot peeling, the focal application and tattooing of higher trichloroacetic acid concentrations; (ii) subcision, the process by which there is separation of the acne scar from the underlying skin; and (iii) fractional laser irradiation. In this pilot study, the efficacy and safety of this method was investigated for the treatment of acne scars. Ten patients received this therapy for a year. Dot peeling and subcision were performed twice 2–3 months apart and fractional laser irradiation was performed every 3–4 weeks. Outcomes were assessed using scar severity scores and patients’ subjective ratings. Acne scarring improved in all of the patients completing this study. Acne scar severity scores decreased by a mean of 55.3%. Eighty percent of the patients felt significant or marked improvement. There were no significant complications at the treatment sites. It would appear that triple combination therapy is a safe and very effective combination treatment modality for a variety of atrophic acne scars.     

The efficacy of fractional CO2 laser in acne scar treatment: A meta‐analysis

Fractional CO₂ laser is a good option for treating acne scars. However, the clinical efficacy of this treatment modality requires further evidence. To perform a meta‐analysis to assess clinical improvements in acne scars with fractional CO₂ laser and non‐CO₂ laser therapies. Databases (PubMed, Embase, Cochrane Library) were searched using the search strategy to identify eligible studies. All statistical analyses were performed using the Review Manager 5.0, and a meta‐analysis was conducted to assess the effects of fractional CO₂ laser used as a treatment for acne scars. Eight studies were included for further analysis. There was no significant difference between fractional CO₂ laser and non‐CO₂ laser therapies in terms of clinical improvement, observer assessment (P = .19), patient assessment (P = .91), and incidence of post‐inflammatory hyperpigmentation (P = .69). The subgroup analyses showed that the duration of follow‐up had little effect on the evaluation of treatment effect. The efficacy of fractional CO₂ laser therapy in acne scars appeared to be equal to that of non‐CO₂ laser therapies. More well designed randomized controlled trials and more credible and standard evaluation criteria are needed, and the efficiency of combination therapy requires further analysis.