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2010年全国第五次结核病流行病学抽样调查报告
引用本文:张懿行, 王伟炳, 李小攀, 李朋, 邓鹏飞. 454例不规则治疗肺结核患者复发的相关因素分析[J]. 上海预防医学, 2019, 31(12): 1015-1019. DOI: 10.19428/j.cnki.sjpm.2019.18842
作者姓名:张懿行  王伟炳  李小攀  李朋  邓鹏飞
作者单位:1.上海市浦东新区疾病预防控制中心, 上海 200136;2.复旦大学公共卫生学院, 上海 200032
基金项目:上海市浦东新区卫生系统优秀青年医学人才培养计划(PWRq2017-33)
摘    要:
目的分析不规则治疗肺结核患者复发的相关因素,为制定提高肺结核重点人群治疗成功率的策略提供参考。方法采集2010-2014年上海市浦东新区的肺结核监测数据,应用单因素及多因素Logistic回归分析454例不规则治疗肺结核患者的复发情况与性别、年龄、初诊结果、登记分类、不规则治疗原因、不规则治疗前规范服药时间及随访干预等因素的相关性。结果单因素分析显示,不同诊断结果、登记分类、不规则治疗原因、干预结果的不规则治疗肺结核患者复发率差异有统计学意义(P < 0.05)。Logistic回归分析显示,涂阳(OR=1.848,95% CI:1.027~3.323)、复治(OR=2.115,95% CI:1.072~4.173)、未成功干预(OR=23.468,95% CI:9.692~56.825)是不规则治疗肺结核患者复发的相关因素(P < 0.05)。结论掌握肺结核重点人群复发的相关因素,采取有针对性的干预措施,对降低肺结核复发率有积极意义。

关 键 词:肺结核  不规则治疗  复发  相关因素
收稿时间:2018-05-06

Risk factors for recurrence of tuberculosis
ZHANG Yi-xing, WANG Wei-bing, LI Xiao-pan, LI Peng, DENG Peng-fei. Related factors for recurrence in 454 tuberculosis patients with irregular treatment[J]. Shanghai Journal of Preventive Medicine, 2019, 31(12): 1015-1019. DOI: 10.19428/j.cnki.sjpm.2019.18842
Authors:ZHANG Yi-xing  WANG Wei-bing  LI Xiao-pan  LI Peng  DENG Peng-fei
Affiliation:1.Pudong New Area Center for Disease Control and Prevention, Shanghai 200136, China;2.School of Public Health, Fudan University, Shanghai 200032, China
Abstract:
ObjectiveTo make analysis on the related factors for recurrence of irregularly treated patients with tuberculosis, providing references for strategy development to improve the treatment success rate of key populations of tuberculosis.MethodsUnivariate and Logistic regression models were used to analyze the correlation between the recurrence of 454 irregularly treated patients and factors such as gender, age, diagnosis, registration classification, causes of irregular treatment, number of months before irregular treatment, results of intervention and others by collecting tuberculosis surveillance data from 2010 to 2014 in Pudong New Area of Shanghai.ResultsUnivariate analysis showed that different diagnosis results, classification as retreatment, causes of irregular treatment, and failure of intervention were statistically different in the recurrence of patients with irregular tuberculosis (P < 0.05).Multiple regression model analysis showed that smear positive (OR=1.848, 95% CI:1.027-3.323), retreatment (OR=2.115, 95% CI:1.072-4.173) and the failure of intervention (OR=23.468, 95% CI:9.692-56.825) were independent related factors for recurrence of tuberculosis patients with irregular treatment (P < 0.05).ConclusionIt is important to reduce the recurrence rate of tuberculosis by controlling related factors in key populations of tuberculosis and taking targeted interventions.
Keywords:tuberculosis  irregular treatment  recurrence  related factors
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