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脊髓背根入髓区毁损术治疗臂丛神经撕脱伤后疼痛
引用本文:陶蔚,陈富勇,胡永生,张晓华,李勇杰.脊髓背根入髓区毁损术治疗臂丛神经撕脱伤后疼痛[J].神经疾病与精神卫生,2010,10(4):334-337.
作者姓名:陶蔚  陈富勇  胡永生  张晓华  李勇杰
作者单位:1. 首都医科大学宣武医院北京功能神经外科研究所,100053
2. 福建医科大学附属第一医院
摘    要:目的 探讨脊髓背根入髓区毁损术治疗臂丛神经撕脱伤后疼痛的疗效及安全性.方法 15例臂丛神经撕脱伤后疼痛患者接受脊髓背根入髓区毁损术治疗.分别于术后2周、6个月和1年采用视觉模拟评分(VAS)、汉密尔顿抑郁(HAMD)和焦虑评分(HAMA)来评估手术疗效.结果 手术早期,100%的患者疗效满意,经过1年的随访,疗效满意率逐渐下降.但是比较术后2周和术后6个月,以及比较术后2周和术后1年的VAS评分,结果 显示无统计学差异.并发症主要包括同侧下肢的轻度无力(3例)和同侧下肢深感觉障碍(3例),在术后6个月都有不同程度的恢复.结论 脊髓背根入髓区毁损术是治疗臂丛神经撕脱伤后疼痛的一种安全、有效的措施.

关 键 词:脊髓背根入髓区  臂丛神经撕脱伤  慢性神经源性疼痛

Microsurgical lesions in the dorsal root entry zone for pain due to brachial plexus avulsion
Institution:TAO Wei, CHEN Fu-yong , HU Yong-sheng , et al. (Beijing Institute of Functional Neurosurgery , Xuan Wu Hospital, Capital Medical University ,Beijing 100053, China )
Abstract:Objective To analyze efficacy and safety of mierosurgical lesions in DREZ in patients with pain due to brachial plexus avulsion. Methods Fifteen patients with intractable deafferentation pain due to brachial plexus avulsion had microsurgical lesion in the dorsal root entry zone (DREZ). The visual analog scale (VAS) , HAMD and HAMA was assessed at 2 week, 6 months and lyear after the surgery. Results The greatest pain relief (100%) was reported immediately after the DREZ procedure. Over the l-year follow-up period, the pain relief effect gradually decreased. There were no significant differences between the pain relief evaluated at 2 week and after 6 months and between the pain relief evaluated at 2 week and after 1 year. The major complications included motor weakness of the ipsilateral lower limb (n=3) and dysfunction of deep sensory of the ipsilateral lower limb (n= 3). These complications can be improved 6 months after surgery. Conclusions Microsurgical lesions in the dorsal root entry zone can be performed to treat refractory pain due to brachial plexus avulsions. It is an effective and safe procedure.
Keywords:Dorsal root entry zone  Braehial plexus avulsion  Chronic neuropathic pain
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