| 网脉橐吾的倍半萜类成分网脉橐吾的倍半萜类成分 |
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| 引用本文： | 檀爱民,何红平,杨虹,张勉,王峥涛,郝小江.网脉橐吾的倍半萜类成分网脉橐吾的倍半萜类成分[J].药学学报,2003,38(12):924-926. |
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| 作者姓名： | 檀爱民 何红平 杨虹 张勉 王峥涛 郝小江 |
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| 作者单位： | 1. 中国药科大学,生药学研究室,江苏,南京,210038
2. 中国科学院,昆明植物研究所,植物化学与植物资源持续利用国家重点实验室,云南,昆明,650204 |
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| 基金项目： | 国家杰出青年基金项目 (3 982 5 12 9) |
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| 摘 要： | 目的研究网脉橐吾(Ligularia dictyoneura)的化学成分。方法应用色谱技术进行分离和纯化,MS,IR,NMR等波谱解析结构。结果从网脉橐吾中分离鉴定了4个倍半萜,分别签定为:ligudicin A (1), ligudicin C (2), ligudicin D (3)和isopetasin (4)。结论1为新化合物,2为新的天然产物,3和4为首次从网脉橐吾中分离得到。
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| 关 键 词： | 菊科 网脉橐吾 倍半萜 ligudicin A |
| 收稿时间： | 2003-01-14 |
Chemical constituents of Ligularia dictyoneura |
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| TAN Ai-min,HE Hong-ping,YANG Hong,ZHANG Mian,WANG Zheng-tao,HAO Xiao-jiang.Chemical constituents of Ligularia dictyoneura[J].Acta Pharmaceutica Sinica,2003,38(12):924-926. |
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| Authors: | TAN Ai-min HE Hong-ping YANG Hong ZHANG Mian WANG Zheng-tao HAO Xiao-jiang |
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| Institution: | Department of Pharmacognosy, China Pharmaceutical University, Nanjing 210038, China. |
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| Abstract: | Aim To study the chemical constituents of Ligularia dictyoneura . Methods Various chromatographic techniques were used to separate and purify the compounds. Their spectral data (MS, IR, NMR) were measured for structure elucidation. Results Four sesquiterpenes were isolated from Ligularia dictyoneura and their structures were identified as ligudicin A (1), ligudicin C (2), ligudicin D (3) and isopetasin (4). Conclusion Compound 1 is a new compound, compound 2 is a new natural product, and compounds 3 and 4 are obtained from Ligularia dictyoneura for the first time. |
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| Keywords: | Compositae Ligularia dictyoneura sesquiterpenes ligudicin A |
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