| 严重腹腔感染脓毒症患儿C-反应蛋白的动态监测及意义 |
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| 引用本文： | 王萍,张丽霞,宫颖新,张丽丽,张铁军,周晓康.严重腹腔感染脓毒症患儿C-反应蛋白的动态监测及意义[J].河北医药,2009,31(21). |
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| 作者姓名： | 王萍 张丽霞 宫颖新 张丽丽 张铁军 周晓康 |
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| 作者单位： | 河北省儿童医院,石家庄市,050031 |
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| 摘 要： | 目的探讨严重腹腔感染脓毒症患儿在外科治疗中C-反应蛋白(CRP)的动态变化规律及其临床意义。方法选择我院严重腹腔感染患儿35例为脓毒症组,同期门诊查体的健康儿童30例为对照组。脓毒症组(于术前和术后第1、5天)、对照组采空腹静脉血及末梢血,应用全自动生化分析仪检测CRP,血细胞计数仪测定外周血白细胞计数。结果脓毒症组术前及术后第5天血清CRP浓度及白细胞计数与对照组比较,差异有统计学意义(P<0.01);脓毒症术后第1、5天血清CRP浓度及白细胞计数与术前比较,差异有统计学意义(P<0.01)。结论严重腹腔感染脓毒症患儿CRP浓度明显升高,经手术干预、合理治疗,CRP逐渐下降,脓毒症控制。CRP可以作为脓毒症辅助诊断及疗效观察指标。
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| 关 键 词： | 脓毒症 C-反应蛋白 儿童 外科治疗 |
The dynamic monitoring of CRP and its significance in children with severe intra-abdominal infection |
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| Institution: | WANG Ping; ZHANG Lixia; GONG Yingxin; et al.Department of Pediatric Surgery; Children's Hospital of Hebei Province; Shijiazhuang 050031; China; |
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| Abstract: | Objective To investigate the dynamic changes of CRP and its clinical significancet in children with severe intra-abdominal infection.Methods The 35 children with severe intra-abdominal infection were chosen in our hospital as sepsis group,30 healthy children were chosen as control group.There was no significant difference in age and sexuality between two groups.The fasting venous blood was taken from 65 children.Automatic biochemistry analyzer was used to detect the levels of CRP,and the counts of leukocyte... |
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| Keywords: | sepsis CRP children surgical therapy |
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