苦瓜茎叶的化学成分研究

目的 研究苦瓜茎叶的化学成分，为进一步开发利用苦瓜茎叶提供依据。方法 采用反复硅胶柱色谱、反相ODS柱色谱、Sephadex LH-20等柱色谱进行分离纯化，通过波谱数据鉴定化合物结构。结果 分离得到1种倍半萜和2种葫芦烷三萜，分别鉴定为催吐萝芙叶醇（1）、kuguacin J（2）、3,23(R)-二羟基-7-乙氧基-19-醛基-5,24-二烯醇（3）。结论 化合物1为首次从该植物中分离得到，化合物3为新化合物，命名为7-乙基苦瓜素Ⅰ。

Chemical constituents in fresh vines and leaves of Momordica charantia

Objective To study the chemical constituents from the fresh vines and leaves of Momordica charantia, and to provide a basis for the further development and utilization of bitter melon whole plant. Methods The chemical constituents were isolated and purified by chromatography on silica gel, ODS silica gel, and Sephadex LH-20 columns, and their structures were determined by spectral data. Results One sesquiterpene and two cucurbitane triterpenoids were obtained and they were identified as vomifoliol (1), kuguacin J (2), and 3,23(R)-dihydroxycucurbita-7-ethoxy-5,24-dien-19-al (3). Conclusion Compound 1 is isolated from M. charantia for the first time and compound 3 is a new compound named 7-ethyl momordicine I.