| 中西医结合治疗帕金森病非运动症状的系统评价与Meta分析 |
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| 引用本文： | 田浩林,田金洲,倪敬年,李婷,魏明清,张学凯,张天清,周梦玲,周沪方,贾冬冬,魏欣如,林乐颖,扎木,姚璇,梁俊杰,时晶.中西医结合治疗帕金森病非运动症状的系统评价与Meta分析[J].天津中医药大学学报,2019,38(2):147-154. |
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| 作者姓名： | 田浩林 田金洲 倪敬年 李婷 魏明清 张学凯 张天清 周梦玲 周沪方 贾冬冬 魏欣如 林乐颖 扎木 姚璇 梁俊杰 时晶 |
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| 作者单位： | 北京中医药大学东直门医院, 北京 100700,北京中医药大学东直门医院, 北京 100700,北京中医药大学东直门医院, 北京 100700,北京中医药大学东直门医院, 北京 100700,北京中医药大学东直门医院, 北京 100700,北京中医药大学东直门医院, 北京 100700,北京中医药大学东直门医院, 北京 100700,北京中医药大学东直门医院, 北京 100700,北京中医药大学东直门医院, 北京 100700,北京中医药大学东直门医院, 北京 100700,北京中医药大学东直门医院, 北京 100700,北京中医药大学东直门医院, 北京 100700,北京中医药大学东直门医院, 北京 100700,北京中医药大学东直门医院, 北京 100700,北京中医药大学东直门医院, 北京 100700,北京中医药大学东直门医院, 北京 100700 |
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| 基金项目： | 帕金森病非运动症状的防治策略研究（Z141107002515019）;帕金森病非运动症状的中医证候特征及中药干预研究（2014-1-4191）;田金洲"111"计划阿尔茨海默症及其神经变性病的中医药防治研究创新引智基地（7010051510001）。 |
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| 摘 要： | 目的]系统评价中西医结合治疗帕金森病非运动症状的临床疗效与安全性。方法]全面检索相关中英文数据库,搜集自建库至2018年7月所有中药联合西医基础治疗与西医基础治疗(和中药安慰剂)的临床随机对照试验,根据纳入标准、排除标准,选择符合标准的相关文献并提取资料,依据Cochrane Handbook对纳入的文献进行质量评价,并采用RevMan5.3软件进行Meta分析。结果]最终纳入24篇RCT,共计1 836例患者,分别采用主要指标及次要指标进行评价。结果显示:NMSS量表MD=-6.19,95%CI=(-7.68,-4.69),Chi2=0.83,DF=3,n=302];NMSQuest量表MD=-2.17,95%CI=(-2.67,-1.68),n=601]UPDRS I量表,未进行Meta分析Chi2=75.91,DF=10,n=882],UPDRS II量表MD=-2.71,95%CI=(-3.34,-2.08),n=1164];PDQ-39量表MD=-7.81,95%CI=(-9.97,-5.64),n=407]。结论]中西医结合治疗帕金森病非运动症状有效,且优于单纯西医基础治疗。
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| 关 键 词： | 帕金森病 非运动症状 中西医结合 系统评价 Meta分析 |
| 收稿时间： | 2018/12/11 0:00:00 |
Integrated traditional Chinese and western medicine for the Non-motor symptoms of parkinson's disease: a systematic review and meta-analysis |
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| TIAN Haolin,TIAN Jinzhou,NI Jingnian,LI Ting,WEI Mingqing,ZHANG Xuekai,ZHANG Tianqing,ZHOU Mengling,ZHOU Hufang,JIA Dongdong,WEI Xinru,LIN Leying,ZHA Mu,YAO Xuan,LIANG Junjie and SHI Jing.Integrated traditional Chinese and western medicine for the Non-motor symptoms of parkinson's disease: a systematic review and meta-analysis[J].Journal of Tianjin University of Traditonal Chinese Medicine,2019,38(2):147-154. |
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| Authors: | TIAN Haolin TIAN Jinzhou NI Jingnian LI Ting WEI Mingqing ZHANG Xuekai ZHANG Tianqing ZHOU Mengling ZHOU Hufang JIA Dongdong WEI Xinru LIN Leying ZHA Mu YAO Xuan LIANG Junjie and SHI Jing |
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| Institution: | Dongzhimen Hospital of Beijing University of Chinese Medicine, Beijing 100700, China,Dongzhimen Hospital of Beijing University of Chinese Medicine, Beijing 100700, China,Dongzhimen Hospital of Beijing University of Chinese Medicine, Beijing 100700, China,Dongzhimen Hospital of Beijing University of Chinese Medicine, Beijing 100700, China,Dongzhimen Hospital of Beijing University of Chinese Medicine, Beijing 100700, China,Dongzhimen Hospital of Beijing University of Chinese Medicine, Beijing 100700, China,Dongzhimen Hospital of Beijing University of Chinese Medicine, Beijing 100700, China,Dongzhimen Hospital of Beijing University of Chinese Medicine, Beijing 100700, China,Dongzhimen Hospital of Beijing University of Chinese Medicine, Beijing 100700, China,Dongzhimen Hospital of Beijing University of Chinese Medicine, Beijing 100700, China,Dongzhimen Hospital of Beijing University of Chinese Medicine, Beijing 100700, China,Dongzhimen Hospital of Beijing University of Chinese Medicine, Beijing 100700, China,Dongzhimen Hospital of Beijing University of Chinese Medicine, Beijing 100700, China,Dongzhimen Hospital of Beijing University of Chinese Medicine, Beijing 100700, China,Dongzhimen Hospital of Beijing University of Chinese Medicine, Beijing 100700, China and Dongzhimen Hospital of Beijing University of Chinese Medicine, Beijing 100700, China |
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| Abstract: | |
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| Keywords: | parkinson''s disease non-motor symptoms integrated Chinese and Western Medicine systematic review meta analysis |
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