| 孕产期抑郁症生物标志物的研究进展 |
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| 引用本文： | 章柳宵,Obore Nathan,虞天一,钱惠勤,张媛,于红.孕产期抑郁症生物标志物的研究进展[J].中国药科大学学报,2022,53(1):120-124. |
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| 作者姓名： | 章柳宵 Obore Nathan 虞天一 钱惠勤 张媛 于红 |
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| 作者单位： | 东南大学医学院，南京 210009,东南大学医学院，南京 210009,东南大学附属中大医院，南京 210009,东南大学附属中大医院，南京 210009,东南大学医学院，南京 210009,东南大学附属中大医院，南京 210009 |
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| 基金项目： | 江苏省妇幼健康科研资助项目（No.F201810） |
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| 摘 要： | 孕产期抑郁症是围产期常见的并发症之一，严重影响母儿身心健康。目前，早期诊断孕产期抑郁症尤为困难，客观有效的生物学标志物对早发现早治疗孕产期抑郁症意义重大。近年来探索孕产期抑郁症早期诊断的生物标志物成为研究热点，主要在性激素、神经内分泌相关激素、免疫炎症分子、遗传及表观遗传学等方面。本文就近年来孕产期抑郁症生物学标志物的研究进展进行综述。
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| 关 键 词： | 孕产期抑郁症 生物学标志物 早期诊断 进展 |
| 收稿时间： | 2021/12/7 0:00:00 |
| 修稿时间： | 2021/12/28 0:00:00 |
Research progress in biological markers of perinatal depression |
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| ZHANG Liuxiao,OBORE Nathan,YU Tianyi,QIAN Huiqin,ZHANG Yuan and YU Hong.Research progress in biological markers of perinatal depression[J].Journal of China Pharmaceutical University,2022,53(1):120-124. |
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| Authors: | ZHANG Liuxiao OBORE Nathan YU Tianyi QIAN Huiqin ZHANG Yuan and YU Hong |
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| Institution: | (Medical School of Southeast University,Nanjing 210009;Southeast University Affiliated Zhongda Hospital,Nanjing 210009,China) |
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| Abstract: | Perinatal depression, one of the most common complications in the perinatal period, has a significant impact on the physical and mental health of mothers and children. At present, it is difficult to diagnose perinatal depression at an early stage, so objective and effective biomarkers are of great significance for the early detection and treatment of perinatal depression. In recent years, the exploration of biomarkers for early diagnosis of perinatal depression has become a hot research topic, mainly in sex hormones, neuroendocrine-related hormones, immuno-inflammatory molecules, genetics, and epigenetics. This article reviews the research progress of the biomarkers of perinatal depression in recent years. |
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| Keywords: | perinatal depression biological markers early diagnosis advances |
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