罗哌卡因复合芬太尼及氟哌利多术后硬膜外镇痛的临床研究

目的：比较不同浓度罗哌卡因在术后硬膜镇痛（PCEA）的临床效果。方法：术后病人90例，随机分为三组：A组0．25％罗哌卡因（n=30)；B组0．15％罗哌卡因（n=30)；C组0．075％罗哌卡因（n=30），三组均加入芬太尼和氟哌利多。首剂负荷量8ml，采用镇痛泵持续量2ml/h，单次按压量每次0.5ml，锁定时间15min。结果：A、B两组间VAS疼痛评分无显著差异（P＞0．05），有较好的镇痛效果。两组病人恶区，呕吐、皮肤瘙痒，呼吸抑制发生率无显著差异（P＞0．05）。B组尿潴留发生率明显低于A组（P＜0．05）。C组镇痛效果不满意，结论：0．15％罗哌卡因复合芬太尼，氟哌利多在PCEA术后镇痛是安全有效的。

Clinical Study of PCEA with Ropivacaine Fentanyl and Droperidol for Postoperative Pain-Reoief

Objective:To compare the clinical effect of different dense of ropivacaine used during PCEA.Method:Ninty postoperative patients,who were randomly divided into three groups,0.25%,0.15% and 0.075% ropivacaine was given in group A,B and C respectively.Fentanyl and Droperidol were added in the local anesthetic solution for each group.A loading dose of 8ml was gvien,which was followed by continuous infusion of 2ml/h,locked time 15min bolus dose 0.5ml.Result:There were no differences in VAS scores between group A and B (P>0.05),have excellent analgesia.There were no remarkable differences between two PCEA groups in nausea,vomiting,respiratory depression and pruritis (P>0.05).The incidence of urinary retention in group B were significantly lower than that in group A (P<0.05).Group C has unsatisfactory analgesia.Conclusion:PCEA with 0.15% ropivacaine,fentanyl and droperidol was safe and effective.