铁蛋白与胎膜早破、早产关系的研究

目的通过测定早产、胎膜早破患者母血清铁蛋白的水平，探讨其与早产、胎膜早破的关系。方法将研究对象分为先兆早产24h内分娩者、24h内未分娩者，未足月胎膜早破组、足月胎膜早破组及对照组，用放射免疫法测定孕妇血清铁蛋白水平并进行比较。结果与对照组比较，先兆早产组铁蛋白均升高，其中24h分娩者铁蛋白水平高于24h未分娩者。与对照组比较，足月、未足月胎膜早破组铁蛋白均升高，2组胎膜早破间铁蛋白水平无明显变化。结论铁蛋白与胎膜早破及早产关系密切，临床上可作为预测早产的指标。

Study of the relationship between serum ferritin and PROM and premature labor

Objective To explore the relationship between maternal serum ferritin and premature labor and premature rupture of membranes(PROM).Methods The 70 subjects were divided into 5 groups: group of threatened premature labor group without labor,threatened premature labor with labor within 24h,normal control pregnancy of comarable periods of gestation group,and the groups of pre-term pregnancy premaure rupture of membranes(PROM)and term pregnancy PROM.The level of serum ferrintin was determinated by radioimmunoassay.Results In contrast to the control,the levels of ferritin in the threatened premature labor were high,higher in the group who delivered within 24h than in the group without labor.The levels of ferritin were higher in the two PROM groups,and there were no apparent differences in ferritin between the two PROM groups.Conclusions Ferritin is closely related to PROM and premature labor,but not to the onset of labor.It can be a marker for predicting premature labor.