| Nimodipine对脑外伤后脑水及脑皮质和血清钙含量的影响 |
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| 引用本文： | 徐如祥,易声禹.Nimodipine对脑外伤后脑水及脑皮质和血清钙含量的影响[J].南方医科大学学报,1992(3). |
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| 作者姓名： | 徐如祥 易声禹 |
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| 作者单位： | 第一军医大学珠江医院神经外科
(徐如祥)，第四军医大学西京医院神经外科(易声禹) |
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| 摘 要： | 本文观察了脑损伤后不同时间大鼠脑水含量和脑皮质及血清钙含量变化,以及Nimodipine对外伤性脑水肿和钙含量变化的影响。结果表明,脑损伤后6h脑白质水含量巳明显增多,为79.87±0.58(P<0.01),伤后48h达峰值,为81.02±0.51:脑皮质水含量稍有增加。脑皮质及血清钙含量均有不同程度升高,以脑皮质升高较为明显,伤后48h高达24.12±10.22mmol/kg干脑,为对照值的1.8倍.应用Nimodipine治疗,可显著降低脑皮质钙含量,伤后立即接受治疗组为16.78±4.98mmol/kg干脑(P<0.05),脑水肿明显减轻,为78.98±0.89(P<0.01)。
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| 关 键 词： | Nimodipine 脑损伤 脑皮质 脑水肿 血清 钙 |
Effect of nimodipine on changes of brain fluid content and calcium in the brain cortex and serum following brain injury |
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| Xu Ruxiang and Yi Shengyu.Effect of nimodipine on changes of brain fluid content and calcium in the brain cortex and serum following brain injury[J].Journal of Southern Medical University,1992(3). |
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| Authors: | Xu Ruxiang and Yi Shengyu |
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| Institution: | Xu Ruxiang and Yi Shengyu
Department of Neurosurgery,Zhnjiang Hospital,First Militery Medical University,GuangZhou Department of Neurosurgery,Xijing Hospital,Fourth Meilitary Medeical University,Xi'an |
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| Abstract: | |
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| Keywords: | nimodipine brain brain injury calcium brain edema |
| 本文献已被 CNKI 等数据库收录！ |
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