滋肾养肝法治疗肾虚肝郁型月经过少的临床观察

【目的】观察滋肾养肝法治疗肾虚肝郁型月经过少的临床疗效。【方法】将51例肾虚肝郁型月经过少患者随机分为治疗组25例和对照组26例,治疗组给予养阴舒肝胶囊(主要由柴胡、白芍、熟地黄、女贞子等中药组成)治疗,对照组给予安慰剂治疗,治疗8周后,根据中医症状评分的改善情况评价2组患者的总体疗效和月经疗效(包括经量、色质、经期的改善情况)。【结果】(1)总体疗效方面:治疗后,治疗组的总有效率为84.0%,明显优于对照组的15.4%,差异有统计学意义(P0.01)。(2)月经疗效方面:治疗组在改善月经量和月经色质方面的总有效率分别为64.0%和68.0%,明显优于对照组的7.7%和15.4%,差异有统计学意义(P0.01);而在改善经期方面,2组差异无统计学意义(P0.05)。【结论】滋肾养肝法治疗肾虚肝郁型月经过少有显著效果,对改善月经量及中医证候均有明显疗效,表明中医药治疗月经过少具有明显优势。

Clinical Observation of Therapy of Nourishing Kidney and Liver for Hypomenorrhea with Syndrome of Kidney Deficiency and Liver Stagnation

Objective To observe the clinical efficacy of therapy of nourishing kidney and liver for the treatment of hypomenorrhea with the syndrome of kidney deficiency and liver stagnation. Methods Fifty-one hypomenorrhea patients with the syndrome of kidney deficiency and liver stagnation were randomized into treatment group(N =25) and control group (N = 26). The treatment group was treated with oral use of Yangyin Shugan Capsules (mainly composed of Radix Bupleuri, Radix Paeoniae Alba, Radix Rehmanniae Preparata, and Fructus Ligustri Lucidi). The control group was given placebo capsules orally. After treatment for 8 weeks , the overall efficiency and therapeutic effect on menstruation of the two groups were evaluated according the changes of traditional Chinese medicine(TCM) symptom scores. Results(1) The total effective rate of the treatment group was 84.0％, and that of the control group was 15.4％, the difference being significant between the two groups (P < 0.01). (2) The effective rate on the menstrual volume and menstrual color and texture of the treatment group was 64.0％, 68.0％, and that of the control group was 7.7％, 15.4％ respectively, the difference being significant(P < 0.01). However, the difference of effect on improving menstrual period was insignificant between the two groups (P > 0.05). Conclusion Therapy of nourishing kidney and liver is effective for the treatment of hypomenorrhea with the syndrome of kidney deficiency and liver stagnation, and has obvious effect on improving menstrual volume and TCM symptoms.