颈椎疾病患者术前高压氧预处理对神经功能恢复的影响

目的探讨颈椎疾病患者术前高压氧预处理对神经功能恢复的影响。方法选取2010年7月～2011年8月长征医院闸北分院确诊为脊髓型颈椎病并且具有脊髓压迫症患者80例作为研究对象,随机分为治疗组与对照组,每组各40例,治疗组在术前1周开始进行高压氧预处理,对照组不进行高压氧预处理,比较两组入院时、术前、术后3 d、术后6个月时日本骨科协会评估治疗分数（JOA）评分及术后改善率、尺神经体感诱发电位（SEP）N1、P1波变化。结果两组患者入院时及术前JOA评分差异无统计学意义（P〉0.05）,治疗组术后3 d、术后6个月JOA评分、改善率明显较对照组高,JOA评分及改善率组间比较差异有统计学意义（P〈0.05）;两组患者术后3 d、术后6个月时的N1、P1波比较,两组差异有统计学意义（P〈0.05）。结论对脊髓型颈椎病患者术前进行高压氧预处理治疗,能促进患者术后神经功能恢复。

Influence of preoperative hyperbaric oxygen pretreatment on neurological function recovery of patients with cervical vertebrae diseases

Objective To investigate the influence of preoperative hyperbaric oxygen pretreatment on neurological function recovery of patients with cervical vertebrae diseases.Methods Eighty patients from July 2010 to August 2011 in Zhabei Branch of Changzheng Hospital,diagnosed as cervical spondylotic myelopathy and with spinal cord compression,were randomly divided into control group and treatment group,respectively 40 cases.Treatment group was pretreated with hyper baric oxygen one week before operation,while control group not pretreated.The improvement rate after operation,changes of N1 and P1 wave in ulnar nerve SEP and treatment assessment scores of JOA on admission,before operation,3 days and 6 months after operation were compared.Results As to JOA scores on admission and before operation,there was no statistic between-group difference（P 0.05）.The JOA scores after operation were significantly improved compared with those before operation.The JOA scores and improvement rate at 3 days and 6 months after operation were significantly higher than those of control group with statistic between-group difference（P 0.05）.As to changes of N1 and P1 wave in ulnar nerve SEP at 3 days and 6 months after operation,there was statistic between-group difference（P 0.05）.Conclusion For patients with cervical spondylotic myelopathy,preoperative hyperbaric oxygen pretreatment can improve their neurological function recovery after operation.