冠状动脉粥样硬化性心脏病患者电解质紊乱与致病危险因素相关性分析

目的探讨冠状动脉粥样硬化性心脏病(CAHD)患者血电解质紊乱的特点及其与CAHD危险因素的相关性。方法 474例疑似CAHD患者根据冠状动脉造影结果分为CAHD组278例和对照组196例(无冠状动脉粥样硬化改变),对比2组患者血Na+、K+、Ca2+和Mg2+水平,分析CAHD组患者血Na+、K+、Ca2+和Mg2+水平与CAHD易患因素的相关性。结果 CAHD组患者血Na+和Ca2+水平显著高于对照组(P<0.01),血K+和Mg2+水平显著低于对照组(P<0.01)。CAHD组患者CAHD易患因素发生率显著高于对照组(P<0.05,P<0.01)。CAHD患者的血Na+和Ca2+水平与高血压呈正相关(P<0.05),血K+和Mg2+水平与高血压呈负相关(P<0.05);CAHD患者的血Na+、K+和Ca2+水平与糖尿病呈负相关(P<0.05),血Mg2+水平与糖尿病呈正相关(P<0.05);血Na+、K+和Ca2+水平与血脂异常呈正相关(P<0.05),血Mg2+水平与血脂异常呈负相关(P<0.05);血Na+、K+、Ca2+和Mg2+水平与高血压并发糖尿病均呈正相关(P<0.05);血Na+、K+和Ca2+水平与高血压并发血脂异常呈正相关(P<0.05),血Mg2+水平与高血压并发血脂异常呈负相关(P<0.05);血Na+、K+、Ca2+和Mg2+水平与糖尿病并发血脂异常均呈正相关(P<0.05);血Na+、K+、Ca2+和Mg2+水平与高血压并发糖尿病和血脂异常呈正相关(P<0.01)。结论 CAHD患者存在电解质紊乱,CAHD患者电解质紊乱与CAHD易患因素有相关性。

Association between electrolyte disturbances and risk factors for patients with coronary atherosclerotic heart disease

Objective To explore the clinical feature of electrolyte disturbances and the association between electrolyte disturbances and the risk factors for patients with coronary atherosclerotic heart disease(CAHD).Methods A total of 474 patients with suspected CAHD were divided into CAHD group(n=278) and control group(196 patients without CAHD) according to the results of coronary arteriongraphy.The levels of serum Na+,K+,Ca2+ and Mg2+ were compared between the two groups;the associations of serum Na+,K+,Ca2+ and Mg2+ levels and the risk factors for CAHD were analyzed.Results Compared with control group,the levels of serum Na+ and Ca2+ in CAHD group were significantly higher(P<0.01),but the levels of serum K+ and Mg2+ in CAHD group were significantly lower(P<0.01).The risk factors incidences in CAHD group were significantly higher than those in control group(P<0.05 or P<0.01).The serum Na+ and Ca2+ levels were positively correlated to hypertension in patients with CAHD(P<0.05),the serum K+ and Mg2+ levels were negatively correlated to hypertension in patients with CAHD(P<0.05).The serum Na+,K+ and Ca2+ levels were negatively correlated to diabetes in patients with CAHD(P<0.05),but the serum Mg2+ level was positively correlated to diabetes in patients with CAHD(P<0.05).The serum Na+,K+ and Ca2+ levels were positively correlated to dyslipidemia(P<0.05);but the serum Mg2+ level was negatively correlated to dyslipidemia(P<0.05).The serum Na+,K+,Ca2+ and Mg2+ levels were positively correlated to hypertension combined with diabetes(P<0.05).The serum Na+,K+ and Ca2+ levels were positively correlated to hypertension combined with dyslipidemia(P<0.05);but the serum Mg2+ level was negatively correlated to hypertension combined with dyslipidemia(P<0.05).The serum Na+,K+,Ca2+ and Mg2+ levels were positively correlated to diabetes combined with dyslipidemia(P<0.05).The serum Na+,K+,Ca2+ and Mg2+ levels were positively correlated to hypertension combined with diabetes and dyslipidemia(P<0.01).Conclusion Electrolyte disturbances may exist in patients with CAHD,the electrolyte disturbances is related to the risk factors for CAHD.