非酒精性脂肪肝与颈动脉粥样硬化的相关性研究

目的探讨非酒精性脂肪肝（NAFL）与颈动脉粥样硬化的相关性。方法选择135例NAFL患者，按严重程度分为轻度组、中度组及重度组，选择60名健康人为对照组，进行颈动脉彩色多普勒超声检查，比较各组患者颈动脉内中膜厚度差异及粥样斑块及动脉狭窄发生率差异，并分析非酒精性脂肪肝患者脂肪肝严重程度与颈动脉狭窄的相关性。结果轻、中、重度组颈动脉内膜中层厚度、颈动脉斑块及颈动脉狭窄发生率均高于正常肝脏组。脂肪肝的严重程度与颈动脉狭窄程度呈正相关关系（r=0．442，P=0．002）。结论非酒精脂肪肝与颈动脉粥样硬化密切相关，对于非酒精性脂肪肝患者应注意颈动脉粥样硬化及狭，苫的可能。

Relationship between Nonalcoholic Fatty Liver and Carotid Atherosclerosis

Objective To investigate relationship between nonalcholic fatty liver（NAFL） and carotid atherosclerosis（CAS）. Methods All of 135 cases of patients with NAFL were selected and randomly divided into low-grade groups, medium-grade groups and grave-grade groups according to pathogenetic condition of NAFL, and 60 health prople＇s were selected as control groups, carotid artery in patients were detected with color doppler ultrasound, intima-media thickness （IMT）, rate of CAS and carotid artery stenosis were contrasted among every groups, and correlation between degree of NAFL and carotid artery stenosis were analized. Results IMT was more thick in low-grade groups, medium-grade groups and grave-grade groups than in control groups, there was a positive correlation between NAFL and carotid artery stenosis （r=0.442,P=0.002）. Conclusion NAFL has a high correlation with CAS, CAS and arotid artery stenosis should be pay close attention in patient.s with NAFL.