| 肝脏再生研究进展 |
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| 引用本文： | 张玉果,南月敏,王泰龄.肝脏再生研究进展[J].医学综述,2012,18(14):2158-2161. |
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| 作者姓名： | 张玉果 南月敏 王泰龄 |
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| 作者单位： | 河北医科大学第三医院中西医结合肝病科;中日友好医院病理科 |
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| 基金项目： | 河北省卫生厅科研基金项目(20110112) |
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| 摘 要： | 肝脏在受到各种因素损伤后迅速表现出巨大的再生能力。肝脏再生是一个涉及多种效应细胞增殖反应的高度协调的过程,参与肝脏再生的细胞种类与肝损伤程度密切相关,包括以肝细胞为主的实质细胞再生和通过启动干细胞再生分化为肝细胞和胆管细胞,多种基因、细胞因子及肝脏微环境以不同的作用机制参与肝脏再生的动态调控过程。现就肝部分切除术后不同种类细胞参与肝再生的研究进展进行简要综述。
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| 关 键 词： | 肝切除术 肝再生 肝细胞 肝卵圆细胞 调控 |
Research Progress in Liver Regeneration |
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| ZHANG Yu-guo,NAN Yue-min,WANG Tai-ling.Research Progress in Liver Regeneration[J].Medical Recapitulate,2012,18(14):2158-2161. |
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| Authors: | ZHANG Yu-guo NAN Yue-min WANG Tai-ling |
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| Institution: | 1.Hepatology Department of Integrated Traditional Chinese and Western Medicine,Hebei Medical University Third Hospital,Shijiazhuang 050051,China;2.Department of Pathology,China-Japan Friendship Hospital,Beijing 100029,China) |
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| Abstract: | Liver can exhibit powerful regenerative capacity when injured by various factors.Liver regeneration is a highly coordinated process involving the proliferative response of many different kinds of cells,which is related to the degree of liver injury,lead to liver regeneration from hepatic parenchyma cell or hepatic oval cell.Many genes and cytokines,also hepatic microenvironment participates in the dynamic regulation of liver regeneration with different mechanisms.Here is to make a review on the areas of the different effector cells in liver regeneration after partial hepatectomy. |
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| Keywords: | Partial hepatectomy Liver regeneration Hepatocyte Hepatic oval cell Regulation |
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