BiPAP治疗慢性阻塞性肺疾病伴中重度Ⅱ型呼吸衰竭失败的危险因素分析

目的：探讨无创正压通气治疗慢性阻塞性肺疾病急性加重期伴中重度Ⅱ型呼吸衰竭失败的危险因素。方法：对本院近年来收治的20例经无创正压通气治疗的慢性阻塞性肺疾病急性加重期伴中重度Ⅱ型呼吸衰竭失败患者的临床资料进行回顾性分析，记录患者一般情况、血气指标、生化指标、治疗评估等基本资料，进行统计学分析。结果：治疗失败的原因对比中，患者年龄大、入院时心率快、血压低、血糖高、日常生活能力评分（ADL）低、并发症发生率高均较治疗成功组明显。结论：二元Logistic回归分析显示年龄、心率、血压、血糖、ADL、并发症均为影响无创正压通气成功与否的独立危险因素，因此临床上可据此采取针对性干预措施。

Failure Analysis of Risk Factors for BiPAP in the Treatment of Chronic Obstructive Pulmonary Disease Patients with Severe Type II Respiratory Failure

Objective： To investigate the effect of noninvasive positive pressure ventilation in the treat- ment of acute exacerbations of chronic obstru type respiratory failure risk factors of failure. ctive pulmonary disease patients with moderate and severe II Method： Clinical data of 20 cases treated in recent years by noninvasive positive pressure ventilation in the treatment of acute exacerbations of chronic obstructive pulmo- nary disease patients with severe respiratory failure in type II in patients were analyzed retrospectively recor- ded the patients in general, blood biochemical index, assessment, treatment and other basic information. Result： The causes of treatment failure in contrast, patients with old age, Faster heart rate at the time of ad- mission, hypotension, high blood sugar, lower activities of daily living score （ ADL }, high incidence of complications were successfully treated group were. Conclusion： It showed that age, heart rate, blood pres- sure, blood glucose, ADL, complications are the effects of noninvasive positive pressure ventilation in the success of independent risk factors, therefore clinically available accordingly for intervention measures.