脑干脑炎20例临床分析

目的探讨脑干脑炎的临床特点、影像学变化与预后的关系。方法对20例临床确诊的脑干脑炎的临床特点、影像学变化及预后作一回顾性分析。结果脑干脑炎多以急性或亚急性起病,以头晕、复视、行走不稳、构音不清等为首发症状。全部患者均有颅神经损害表现,以单侧颅神经损害为主(65.0%)。临床定位病灶单发8例(40.0%),多发12例(60.0%),MRI与临床定位相符率低。经及时治疗大部分患者预后良好。结论脑干脑炎的诊断主要根据临床特点,其预后取决于病变的部位、程度以及能否及早诊治等因素。

Clinical analysis for 20 patients with brainstem encephalitis

Objective To investigate the characteristics, neuroimaging and prognosis of brainstem encephalitis (BE).Methods The clinical characteristics,neuroimaging and prognosis in 20 patients with BE were retrospectively analyzed.Results BE was acute or subacute onset.The initial neurological manifestation was dizzy and diplopia in 7 cases,ataxia in 6 cases,anarthria in 5 cases and unconsciousness in 2 cases. The main clinical characteristics in 20 patients were involved in cranial nerves,and the lesion of 65% patients in cranial nerves was unilateral. According to the clinical localization,8 cases (40.0%) had single lesion,the others (60.0%) had more than one lesions. The corresponding rates of lesions detected by MRI to the clinical localization were considerably low. The prognosis of most patients with BE were good after being treated timely.Conclusion The diagnose of BE depends on the clinical characteristics. Its prognosis depends on several factors,such as the region and degree of lesions,and whether the patients are treated timely.