| 牛磺酸对兔心肌缺血再灌注后血液流变学的影响 |
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| 引用本文： | 金寒,鄢文海,李灵红.牛磺酸对兔心肌缺血再灌注后血液流变学的影响[J].郑州大学学报(医学版),2000,35(1):49-50. |
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| 作者姓名： | 金寒 鄢文海 李灵红 |
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| 作者单位： | |
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| 基金项目： | 河南省科技攻关基金资助项目! 934022000 |
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| 摘 要： | Aim To
investigate the protective effect of taurine on hemorheologic feature,we reproduced the
ischemic reperfused myocardium in rabbits. Methods Twenty rabbits were divided into 2
groups. Group 1(control group) no treatment was given during the 45 min ischemia and 180
min reperfusion. Group 2 (Taurine group) 5 min before reperfusion, taurine was given to
rabbits in the bolus of 140 g/kg body-weight. The blood samples were taken before ischemia
and at the time of reperfusion for 180 min to be insected the fallowing parameters.
Rusults Whole blood viscosity at the high or low sheer was deteriorited significantly(P＜0.
05) at the point of reperfusion for 180 min as compared with those before ischemia in
control group， but those parameters were ameliorated in Taurin group as compared with
those in control group at time of 180 min reperfusion.Condusion Tourin can improve the
hemorheologic condition to protect ischemic reperfusion myocardium．
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| 关 键 词： | 血液流变学 血液粘度 牛磺酸 心肌再灌注损伤 |
Ameliorative effect of taurine on hemorheologic feature after ischemic neperfused myocardium in rabbits |
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| JIN Han ,YAN Wenhai ,LI Linghong ,YUE Hesheng ,LI Yongxin ,YANG Ying ,TANG Ning ,WANG Baisheng Medical Laboratory Center,Henan Medical University,Zhengzhou.Ameliorative effect of taurine on hemorheologic feature after ischemic neperfused myocardium in rabbits[J].Journal of Zhengzhou University: Med Sci,2000,35(1):49-50. |
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| Authors: | JIN Han YAN Wenhai LI Linghong YUE Hesheng LI Yongxin YANG Ying TANG Ning WANG Baisheng Medical Laboratory Center Henan Medical University Zhengzhou |
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| Institution: | JIN Han 1),YAN Wenhai 2),LI Linghong 3),YUE Hesheng 1),LI Yongxin 1),YANG Ying 1),TANG Ning 2),WANG Baisheng 1) 1) Medical Laboratory Center,Henan Medical University,Zhengzhou 450052 2) Department of Path |
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| Abstract: | Aim: To investigate the protective effect of taurine on hemorheologic feature,we reproduced the ischemic reperfused myocardium in rabbits. Methods: Twenty rabbits were divided into 2 groups. Group 1(control group): no treatment was given during the 45 min ischemia and 180 min reperfusion. Group 2 (Taurine group): 5 min before reperfusion, taurine was given to rabbits in the bolus of 140 g/kg body weight. The blood samples were taken before ischemia and at the time of reperfusion for 180 min to be insected the fallowing parameters. Rusults: Whole blood viscosity at the high or low sheer was deteriorited significantly( P <0. 05) at the point of reperfusion for 180 min as compared with those before ischemia in control group, but those parameters were ameliorated in Taurin group as compared with those in control group at time of 180 min reperfusion.Condusion: Tourin can improve the hemorheologic condition to protect ischemic reperfusion myocardium. |
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| Keywords: | hemorheology blood viscosity taurine myocardial reperfusion injury |
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