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豫医无毛小鼠近交系毛色基因遗传学测试
引用本文:章金涛,康巧珍,杜献堂,王纯耀,杜春燕,李洪涛,祝庆蕃.豫医无毛小鼠近交系毛色基因遗传学测试[J].郑州大学学报(医学版),2001,36(6):697-698.
作者姓名:章金涛  康巧珍  杜献堂  王纯耀  杜春燕  李洪涛  祝庆蕃
作者单位:河南医科大学实验动物中心,
基金项目:国家自然科学基金资助项目 39970119
摘    要:目的考核豫医无毛小鼠(YYHL)近交系纯化程度及毛色基因型.方法用复隐性基因小鼠DBA/2、615分别对YYHL近交系进行了毛色基因测试.结果和结论杂交所生的F1代全部为野生色,表明其毛色基因为纯合,其基因型为AABBccDD.豫医无毛小鼠近交系已达到近交系的国际标准.

关 键 词:豫医无毛小鼠    近交系    毛色基因
修稿时间:2001年3月16

Genetic test on coat color gene of Yuyi hairless inbred strain m ice
ZHANG Jintao,KANG Qiaozhen,DU Xiantang,WANG Chunyao,DU Chunyan,LI Hongtao,ZHU Qingfan Laboratory Animal Center,Henan Medical University,Zhengzhou.Genetic test on coat color gene of Yuyi hairless inbred strain m ice[J].Journal of Zhengzhou University: Med Sci,2001,36(6):697-698.
Authors:ZHANG Jintao  KANG Qiaozhen  DU Xiantang  WANG Chunyao  DU Chunyan  LI Hongtao  ZHU Qingfan Laboratory Animal Center  Henan Medical University  Zhengzhou
Institution:ZHANG Jintao,KANG Qiaozhen,DU Xiantang,WANG Chunyao,DU Chunyan,LI Hongtao,ZHU Qingfan Laboratory Animal Center,Henan Medical University,Zhengzhou 450052
Abstract:Aim:To study the homozygosity of inbred strain and genotype of coat color gene of Yuyi hairless mice.Methods:The coat color genes were tested by mating inbred strain mice with DBA/2,615 mice carrying the multiple recessive gene separately.Results and Conclusion: The first filial generation were all agouti,which indicated that the coat color genes of inbred strain were homozygotes,and the genotype was AABBccDD.It is showed that Yuyi hairless inbred strain mice have reached the international standards of inbred strain in the case of coat color.
Keywords:Yuyi hairless mice  inbred strain  coat color gene
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