| 双歧杆菌及其细胞壁对荷瘤小鼠干扰素的体内诱导 |
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| 引用本文： | 潘浩,史俊华,阮国瑞,赵宇,张雪萍.双歧杆菌及其细胞壁对荷瘤小鼠干扰素的体内诱导[J].东南大学学报(医学版),1999(1). |
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| 作者姓名： | 潘浩 史俊华 阮国瑞 赵宇 张雪萍 |
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| 作者单位： | 南京铁道医学院微生物学教研室，江苏省卫生防疫站防疫科 |
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| 摘 要： | 目的：观察双歧杆菌及其细胞壁（Ｂ－ＣＷ）对干扰素（ＩＦＮ）诱导而发挥的抗肿瘤作用。方法：荷Ｓ１８０肿瘤小鼠经双歧杆菌及其细胞壁治疗后，收集腹腔巨噬细胞，采用细胞病变抑制法检测培养上清的ＩＮＦ活性；结果：双歧杆菌及其细胞壁均能提高荷瘤小鼠机体内ＩＦＮ的活性。结论：两者都能够通过增强机体的ＩＦＮ活性来发挥抗肿瘤作用
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| 关 键 词： | 双歧杆菌 细胞壁 干扰素 抗肿瘤作用 |
The Effect of Bifidobacterium and Its Cell Wall on the Induction of IFN in Vivo |
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| Pan Hao,Shi Junhua,Ruan Guorui,Zhao Yu,Zhang Xueping.The Effect of Bifidobacterium and Its Cell Wall on the Induction of IFN in Vivo[J].Journal of Southeast Univ: Medical Sci Ed,1999(1). |
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| Authors: | Pan Hao Shi Junhua Ruan Guorui Zhao Yu Zhang Xueping |
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| Abstract: | Objective:A strain of Bifidobacterium and its cell wall were used to treat mice bearing S180 sarcoma in order to investigate the anti-tumor effect of them.Method:After being induced in vivo for ten days,macrophages were harvested and then interferon(IFN) of the supernatant was measured.Result:Both Bifidobacterium and its cell wall can improve the activity of IFN.Conclusion: Bifidobacterium and its cell wall can inhibit the growth of the tumor by enhancing the activity of IFN in vivo. |
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| Keywords: | bifidobacterium cell wall interferon anti-tumor effect |
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