针刺内关穴对窦房结功能的影响

目的:为临床运用内关穴治疗心脏病提供依据。方法:将50例心脏病患者随机分为2组。非阻断组35例,分别于针刺内关穴前后采用食道左房调搏技术测定窦房结恢复时间(SNRT)、窦房传导时间(SACT)、窦房结有效不应期(SNERP)和心率(HR);阻断组15例,用静脉注射心得安和阿托品进行植物神经阻断,分别于阻断前和针刺后测定SNRT、SACT、SNERP和固有心率(IHR)。结果:非阻断组针刺前后比较,SACT、SNERP和HR差异均有统计学意义(均P<0.05),而SNRT差异无统计学意义(P>0.05)。阻断组针刺前后比较,SNRT、SACT和SNERP差异均无统计学意义,而IHR前后差异有统计学意义(P<0.05)。结论:针刺内关穴对窦房结功能有显著作用,其机制可能与针刺内关对窦房结的自主神经具有双相调节作用有关。

Effects of acupuncture at Neiguan (PC 6) on function of sinoatrial node

Objective To observe effects of acupuncture at Neiguan(PC 6) on function of sinoatrial node,so as to provide experimental basis for clinical application of Neiguan(PC 6) to treatment of heart diseases.Methods Fifty cases of heart diseases were randomly divided into 2 groups,a no-blocking group(n=35) and a blocking group(n=15).In the no-blocking group,sinoatrial node recovery time(SNRT),sinoatrial conduction time(SACT),sinoatrial node effective refractory period(SNERP) and heart rate(HR) were determined by using esophagus-left cardiac atrium regulating pulsation technique before and after acupuncture at Neiguan(PC 6);and in the blocking group,the vegetative nerve was blocked by intravenous injection of Propanolol and Atropine,and then SNRT,SACT,SNERP and intrinsic heart rate(IHR) were detected before and after acupuncture.Results In the no-blocking group there were significant differences in SACT,SNERP and HR(all P<0.05) and no significant difference in SNRT(P>0.05) before and after treatment.In the blocking group,there were no significant differences in SNRT,SACT and SNERP and a significant difference in IHR before and after acupuncture(P<0.05).Conclusion Acupuncture at Neiguan(PC 6) has a significant effect on function of sinoatrial node,and the mechanism is possibly related with the bidirectional regulative action of acupuncture at Neiguan(PC 6) on the autonomic nerve in the sinoatrial node.