针刺肝胆经穴治疗偏头痛:多中心随机对照研究

目的:评价针刺肝胆经腧穴治疗偏头痛的临床疗效.方法:采用多中心、随机、对照的方法,将253例偏头痛患者随机分为针刺组和西药组;针刺组以针刺肝胆经腧穴治疗,穴取太冲、阳陵泉、风池、曲泉为主;西药组采用盐酸氟桂利嗪(西比灵)片剂口服治疗,共4个疗程.观察两组治疗后3月和6月总体疗效和治疗前后头痛积分,1年后随访观察两组疗效稳定性.结果:两组治疗后头痛平均发作次数和平均持续时间均较治疗前明显改善(均P<0.01),治疗后两组比较,针刺组改善程度优于西药组(均P<0.05).针刺组治疗后和治疗后3个月、6个月止痛总有效率分别为93.0%、93.0%、87.7%,优于西药组的85.6%、86.5%、69.2 9/6(均P<0.01);1年后疗效稳定性针刺组明显优于西药组(P<0.05).结论:针刺肝胆经穴治疗偏头痛是安全、有效的,且远期疗效稳定.

Acupuncture at points of The Liver and Gallbladder Meridians for treatment of migraine: a multi-center randomized and controlled study

Objective To investigate the therapeutic effect and safety of acupuncture at points of The Liver and Gallbladder Meridians for treatment of migraine. Methods Multi-central, randomized and controlled trial was used and 253 cases of migraine were divided into an acupuncture group and a western medicine group. The acupuncture group was treated with acupuncture at points of The Liver and Gallbladder Channels with Taichong (LR 3), Yang-lingquan (GB 34) , Fengchi (GB 20) , Ququan (LR 8) selected as main points, and the western medicine group with oral administration of Flunarizine tablets for 4 therapeutic courses. The total therapeutic effects 3 and 6 months after the treatment, the scores of various symptoms of migraine before and after treatment, and the stability of therapeutic effect in one-year following-up survey were observed in the two groups. Results After treatment, mean times and duration of the headache attack were significantly improved in the two groups (all P<0. 01) with the acupuncture group better than the western medicine group (P<0. 05). The total effective rates for stopping pain after treatment, 3 months and 6 months after treatment in the acupuncture group were 93. 0%, 93. 0% and 87. 7% , respectively, which were better than 85. 6%, 86. 5% and 69. 2% in the western medication group (all F<0. 01). One year later, the stability of the therapeutic effect in the acupuncture group was better than that in the western medicine group (P<0. 05); the adverse reaction and the compliance in the acupuncture group were significantly superior to those in the western medicine group. Conclusion Acupuncture at points of The Liver and Gallbladder Meridians for treatment of migraine is safe, effective, and with stable long-term therapeutic effect.