| 肺岩宁颗粒治疗精气两亏型中晚期肺腺癌的临床研究 |
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| 引用本文： | 王立芳,蔡玥娇,周航,徐振晔,王中奇,邓海滨,吴继,赵晓珍,王少墨,苏婉.肺岩宁颗粒治疗精气两亏型中晚期肺腺癌的临床研究[J].上海中医药杂志,2018,52(4):49-52. |
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| 作者姓名： | 王立芳 蔡玥娇 周航 徐振晔 王中奇 邓海滨 吴继 赵晓珍 王少墨 苏婉 |
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| 作者单位： | 上海中医药大学附属龙华医院肿瘤科; |
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| 基金项目： | 上海市浦东新区卫计委联合攻关项目(PW2017D-4)；上海市科委科研项目(16401900600)；上海市教委科研创新计划项目(2017-01-07-00-10-E00064) |
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| 摘 要： | 目的观察肺岩宁颗粒治疗精气两亏型中晚期肺腺癌的临床疗效。方法采用前瞻性随机对照研究,将100例精气两亏型中晚期肺腺癌患者随机分为治疗组(49例)与对照组(51例)。治疗组予肺岩宁颗粒,对照组予肺岩宁颗粒模拟剂。两组疗程均为2个月,观察近期疗效及用药安全性,比较中医证候、卡氏评分、体质量及血清肿瘤标志物的变化情况。结果 (1)最终完成试验者,治疗组44例,对照组43例。(2)治疗组、对照组疾病控制率分别为79.5%、53.5%;组间疾病控制率比较,治疗组明显优于对照组(P0.05)。(3)治疗组、对照组中医证候改善率分别为81.8%、23.3%;组间中医证候改善率比较,治疗组明显优于对照组(P0.05)。(4)治疗组、对照组卡氏评分总有效率分别为93.2%、65.1%;组间卡氏评分总有效率比较,治疗组明显优于对照组(P0.05)。治疗组、对照组体质量总有效率分别为79.5%、69.8%;组间体质量总有效率比较差异无统计学意义(P0.05)。(5)组间治疗后比较,CA125、CA50水平差异有统计学意义,治疗组明显低于对照组(P0.05)。(6)两组不良反应发生率比较,差异无统计学意义(P0.05)。结论肺岩宁颗粒治疗精气两亏型中晚期肺腺癌的临床疗效满意,可明显稳定患者病情,改善其临床症状,提高其生活质量。
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| 关 键 词： | 肺腺癌 中晚期 肺岩宁 益气养精 肿瘤标志物 生活质量 |
| 收稿时间： | 2017/11/18 0:00:00 |
Clinical study of Feiyanning Granule in the treatment of advanced lung adenocarcinoma with syndrome of deficiency of both essence and qi |
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| WANG Lifang,CAI Yuejiao,ZHOU Hang,XU Zhenye,WANG Zhongqi,DENG Haibin,WU Ji,ZHAO Xiaozhen,WANG Shaomo and SU Wan.Clinical study of Feiyanning Granule in the treatment of advanced lung adenocarcinoma with syndrome of deficiency of both essence and qi[J].Shanghai Journal of Traditional Chinese Medicine,2018,52(4):49-52. |
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| Authors: | WANG Lifang CAI Yuejiao ZHOU Hang XU Zhenye WANG Zhongqi DENG Haibin WU Ji ZHAO Xiaozhen WANG Shaomo and SU Wan |
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| Institution: | Department of Oncology,Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200032,China,Department of Oncology,Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200032,China,Department of Oncology,Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200032,China,Department of Oncology,Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200032,China,Department of Oncology,Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200032,China,Department of Oncology,Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200032,China,Department of Oncology,Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200032,China,Department of Oncology,Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200032,China,Department of Oncology,Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200032,China and Department of Oncology,Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200032,China |
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| Abstract: | |
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| Keywords: | lung adenocarcinoma advanced stage Feiyanning Granule benefiting qi and nourishing essence tumor marker quality of life |
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